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Gene Review: 

Rabep1  -  rabaptin, RAB GTPase binding effector...

Rattus norvegicus

Synonyms: Rab GTPase-binding effector protein 1, Rabaptin-5, Rabaptin-5alpha, Rabpt5, Rabpt5a
 
 
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High impact information on Rabep1

  • The GGA-Rabaptin-5 interaction decreases binding of clathrin to the GGA-hinge domain, and expression of green fluorescent protein (GFP)-Rabaptin-5 shifts the localization of endogenous GGA1 and associated cargo to enlarged early endosomes [1].
  • We also analyzed the following proteins involved in endocytosis: clathrin, alpha-adaptin, beta-adaptin, and rabaptin-5 [2].

References

  1. Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex. Mattera, R., Arighi, C.N., Lodge, R., Zerial, M., Bonifacino, J.S. EMBO J. (2003) [Pubmed]
  2. The expression of endosomal rab proteins correlates with endocytic rate in rat liver cells. Juvet, L.K., Berg, T., Gjøen, T. Hepatology (1997) [Pubmed]
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