Gene Review:
TERF2IP - telomeric repeat binding factor 2,...
Homo sapiens
Synonyms:
DRIP5, Dopamine receptor-interacting protein 5, PP8000, RAP1, RAP1 homolog, ...
- Expression of MRE11 complex (MRE11, RAD50, NBS1) and hRap1 and its relation with telomere regulation, telomerase activity in human gastric carcinomas. Matsutani, N., Yokozaki, H., Tahara, E., Tahara, H., Kuniyasu, H., Kitadai, Y., Haruma, K., Chayama, K., Tahara, E., Yasui, W. Pathobiology (2001)
- DOCK4, a GTPase activator, is disrupted during tumorigenesis. Yajnik, V., Paulding, C., Sordella, R., McClatchey, A.I., Saito, M., Wahrer, D.C., Reynolds, P., Bell, D.W., Lake, R., van den Heuvel, S., Settleman, J., Haber, D.A. Cell (2003)
- Elevation of cyclic adenosine 3',5'-monophosphate potentiates activation of mitogen-activated protein kinase by growth factors in LNCaP prostate cancer cells. Chen, T., Cho, R.W., Stork, P.J., Weber, M.J. Cancer Res. (1999)
- Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia. Dupuy, A.J., Morgan, K., von Lintig, F.C., Shen, H., Acar, H., Hasz, D.E., Jenkins, N.A., Copeland, N.G., Boss, G.R., Largaespada, D.A. J. Biol. Chem. (2001)
- B-Raf/Rap1 signaling, but not c-Raf-1/Ras, induces the histidine decarboxylase promoter in Helicobacter pylori infection. Wessler, S., Rapp, U.R., Wiedenmann, B., Meyer, T.F., Schöneberg, T., Höcker, M., Naumann, M. FASEB J. (2002)
- Abnormalities of cyclic adenosine monophosphate signaling in platelets from untreated patients with bipolar disorder. Perez, J., Tardito, D., Mori, S., Racagni, G., Smeraldi, E., Zanardi, R. Arch. Gen. Psychiatry (1999)
- The cAMP-dependent protein kinase substrate Rap1 in platelets from patients with obsessive compulsive disorder or schizophrenia. Tardito, D., Maina, G., Tura, G.B., Bogetto, F., Pioli, R., Ravizza, L., Racagni, G., Perez, J. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. (2001)
- Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas. Sawada, Y., Tamada, M., Dubin-Thaler, B.J., Cherniavskaya, O., Sakai, R., Tanaka, S., Sheetz, M.P. Cell (2006)
- Identification of human Rap1: implications for telomere evolution. Li, B., Oestreich, S., de Lange, T. Cell (2000)
- Regulation of immune responses and hematopoiesis by the rap1 signal. Minato, N., Kometani, K., Hattori, M. Adv. Immunol. (2007)
- Linking Rap to cell adhesion. Bos, J.L. Curr. Opin. Cell Biol. (2005)
- Zinc finger protein overexpressed in colon carcinoma interacts with the telomeric protein hRap1. Antoine, K., Ferbus, D., Kolahgar, G., Prospéri, M.T., Goubin, G. J. Cell. Biochem. (2005)
- The human Rap1 protein complex and modulation of telomere length. O'Connor, M.S., Safari, A., Liu, D., Qin, J., Songyang, Z. J. Biol. Chem. (2004)
- Telomere binding of the Rap1 protein is required for meiosis in fission yeast. Chikashige, Y., Hiraoka, Y. Curr. Biol. (2001)
- Mammalian meiotic telomeres: protein composition and redistribution in relation to nuclear pores. Scherthan, H., Jerratsch, M., Li, B., Smith, S., Hultén, M., Lock, T., de Lange, T. Mol. Biol. Cell (2000)
- Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation. Medeiros, R.B., Dickey, D.M., Chung, H., Quale, A.C., Nagarajan, L.R., Billadeau, D.D., Shimizu, Y. Immunity (2005)
- Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. Bivona, T.G., Wiener, H.H., Ahearn, I.M., Silletti, J., Chiu, V.K., Philips, M.R. J. Cell Biol. (2004)
- Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors. Arthur, W.T., Quilliam, L.A., Cooper, J.A. J. Cell Biol. (2004)
- Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex. Béranger, F., Goud, B., Tavitian, A., de Gunzburg, J. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Recognition of telomeric DNA. König, P., Rhodes, D. Trends Biochem. Sci. (1997)
- Rap1 controls cell adhesion and cell motility through the regulation of myosin II. Jeon, T.J., Lee, D.J., Merlot, S., Weeks, G., Firtel, R.A. J. Cell Biol. (2007)
- Sequential regulation of the small GTPase Rap1 in human platelets. Franke, B., van Triest, M., de Bruijn, K.M., van Willigen, G., Nieuwenhuis, H.K., Negrier, C., Akkerman, J.W., Bos, J.L. Mol. Cell. Biol. (2000)
- Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras. Schmitt, J.M., Stork, P.J. J. Biol. Chem. (2002)
- Fission yeast Rap1 homolog is a telomere-specific silencing factor and interacts with Taz1p. Park, M.J., Jang, Y.K., Choi, E.S., Kim, H.S., Park, S.D. Mol. Cells (2002)
- Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase. van Overbeek, M., de Lange, T. Curr. Biol. (2006)
- Telomere repeat binding factors TRF1, TRF2, and hRAP1 modulate replication of Epstein-Barr virus OriP. Deng, Z., Atanasiu, C., Burg, J.S., Broccoli, D., Lieberman, P.M. J. Virol. (2003)
- Combinatorial effect of T-cell receptor ligation and CD45 isoform expression on the signaling contribution of the small GTPases Ras and Rap1. Czyzyk, J., Leitenberg, D., Taylor, T., Bottomly, K. Mol. Cell. Biol. (2000)
- Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent inhibition of IL-5 from human T lymphocytes is not mediated by the cAMP-dependent protein kinase A. Staples, K.J., Bergmann, M., Tomita, K., Houslay, M.D., McPhee, I., Barnes, P.J., Giembycz, M.A., Newton, R. J. Immunol. (2001)