Gene Review:
Gabbr1 - gamma-aminobutyric acid (GABA) B receptor, 1
Mus musculus
Synonyms:
GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABAB1, GABABR1, ...
- Neural network of structures in which GABAB receptors regulate absence seizures in the lethargic (lh/lh) mouse model. Hosford, D.A., Lin, F.H., Kraemer, D.L., Cao, Z., Wang, Y., Wilson, J.T. J. Neurosci. (1995)
- Hypothermia induced by baclofen, a possible index of GABAB receptor function in mice, is enhanced by antidepressant drugs and ECS. Gray, J.A., Goodwin, G.M., Heal, D.J., Green, A.R. Br. J. Pharmacol. (1987)
- Differential sensitivity to the motor and hypothermic effects of the GABA B receptor agonist baclofen in various mouse strains. Jacobson, L.H., Cryan, J.F. Psychopharmacology (Berl.) (2005)
- Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices of GABAB1 receptor subunit knockout mice. Brown, J.T., Gill, C.H., Farmer, C.E., Lanneau, C., Randall, A.D., Pangalos, M.N., Collingridge, G.L., Davies, C.H. Epilepsy Res. (2003)
- GABAB receptor activation inhibits Ca2(+)-activated 86Rb-efflux in cultured spinal cord neurons via G-protein mechanism. Kamatchi, G.L., Ticku, M.K. Brain Res. (1990)
- The role of GABAB receptors in mediating the stimulatory effects of ethanol in mice. Humeniuk, R.E., White, J.M., Ong, J. Psychopharmacology (Berl.) (1993)
- Increased GABAB receptor function in mouse frontal cortex after repeated administration of antidepressant drugs or electroconvulsive shocks. Gray, J.A., Green, A.R. Br. J. Pharmacol. (1987)
- Reversal of scopolamine-induced amnesia by the GABAB receptor antagonist CGP 35348 in the mouse. Bianchi, M., Panerai, A.E. Brain research. Cognitive brain research. (1993)
- Light induces chromatin modification in cells of the mammalian circadian clock. Crosio, C., Cermakian, N., Allis, C.D., Sassone-Corsi, P. Nat. Neurosci. (2000)
- Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice. Slesinger, P.A., Stoffel, M., Jan, Y.N., Jan, L.Y. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Species-specific class I gene expansions formed the telomeric 1 mb of the mouse major histocompatibility complex. Takada, T., Kumánovics, A., Amadou, C., Yoshino, M., Jones, E.P., Athanasiou, M., Evans, G.A., Fischer Lindahl, K. Genome Res. (2003)
- Cerebellar GABAB receptors modulate function of GABAA receptors. Hahner, L., McQuilkin, S., Harris, R.A. FASEB J. (1991)
- GABAA receptor activation attenuates excitotoxicity but exacerbates oxygen-glucose deprivation-induced neuronal injury in vitro. Muir, J.K., Lobner, D., Monyer, H., Choi, D.W. J. Cereb. Blood Flow Metab. (1996)
- gamma-Butyrolactone-induced absence-like seizures increase nuclear CRE- and AP-1 DNA-binding activities in mouse brain. Ishige, K., Aizawa, M., Ito, Y., Fukuda, H. Neuropharmacology (1996)
- Involvement of a GABAergic mechanism in the pharmacologic action of phenytoin. Chweh, A.Y., Swinyard, E.A., Wolf, H.H. Pharmacol. Biochem. Behav. (1986)
- The GABAB-receptor antagonist, CGP 35348, antagonises gamma-hydroxybutyrate- and baclofen-induced alterations in locomotor activity and forebrain dopamine levels in mice. Nissbrandt, H., Engberg, G. Journal of neural transmission (Vienna, Austria : 1996) (1996)
- The murine GABA(B) receptor 1: cDNA cloning, tissue distribution, structure of the Gabbr1 gene, and mapping to chromosome 17. Lamp, K., Humeny, A., Nikolic, Z., Imai, K., Adamski, J., Schiebel, K., Becker, C.M. Cytogenet. Cell Genet. (2001)
- Ambient GABA constrains the strength of GABAergic synapses at Cajal-Retzius cells in the developing visual cortex. Kirmse, K., Kirischuk, S. J. Neurosci. (2006)
- Pacemaker channels in mouse thalamocortical neurones are regulated by distinct pathways of cAMP synthesis. Frère, S.G., Lüthi, A. J. Physiol. (Lond.) (2004)
- Characteristics of GABAB receptor binding sites on rat whole brain synaptic membranes. Bowery, N.G., Hill, D.R., Hudson, A.L. Br. J. Pharmacol. (1983)
- GABAB receptor expression and function in olfactory receptor neuron axon growth. Priest, C.A., Puche, A.C. J. Neurobiol. (2004)
- GABAB receptor-mediated effects in synaptosomes of lethargic (lh/lh) mice. Lin, F.H., Wang, Y., Lin, S., Cao, Z., Hosford, D.A. J. Neurochem. (1995)
- Postnatal development of GABAB receptor-mediated modulation of voltage-activated Ca2+ currents in mouse brain-stem neurons. Zhang, W., Elsen, F., Barnbrock, A., Richter, D.W. Eur. J. Neurosci. (1999)
- Activation of interneurons at the stratum oriens/alveus border suppresses excitatory transmission to apical dendrites in the CA1 area of the mouse hippocampus. Yanovsky, Y., Sergeeva, O.A., Freund, T.F., Haas, H.L. Neuroscience (1997)
- Gene expression differences in mice divergently selected for methamphetamine sensitivity. Palmer, A.A., Verbitsky, M., Suresh, R., Kamens, H.M., Reed, C.L., Li, N., Burkhart-Kasch, S., McKinnon, C.S., Belknap, J.K., Gilliam, T.C., Phillips, T.J. Mamm. Genome (2005)
- gamma-aminobutyric acid B receptors are negatively coupled to adenylate cyclase in brain, and in the cerebellum these receptors may be associated with granule cells. Wojcik, W.J., Neff, N.H. Mol. Pharmacol. (1984)
- Functional coupling of presynaptic GABAB receptors with voltage-gated Ca2+ channel: regulation by protein kinases A and C in cultured spinal cord neurons. Kamatchi, G.L., Ticku, M.K. Mol. Pharmacol. (1990)
- gamma-Hydroxybutyric acid increases intracellular Ca2+ concentration and nuclear cyclic AMP-responsive element- and activator protein 1 DNA-binding activities through GABAB receptor in cultured cerebellar granule cells. Ito, Y., Ishige, K., Zaitsu, E., Anzai, K., Fukuda, H. J. Neurochem. (1995)
- Synaptic GABAergic and glutamatergic mechanisms underlying alcohol sensitivity in mouse hippocampal neurons. Proctor, W.R., Diao, L., Freund, R.K., Browning, M.D., Wu, P.H. J. Physiol. (Lond.) (2006)
- Role of GABAB receptors in intracellular Ca2+ homeostasis and possible interaction between GABAA and GABAB receptors in regulation of transmitter release in cerebellar granule neurons. Kardos, J., Elster, L., Damgaard, I., Krogsgaard-Larsen, P., Schousboe, A. J. Neurosci. Res. (1994)
- Rapid signaling of estrogen in hypothalamic neurons involves a novel G-protein-coupled estrogen receptor that activates protein kinase C. Qiu, J., Bosch, M.A., Tobias, S.C., Grandy, D.K., Scanlan, T.S., Ronnekleiv, O.K., Kelly, M.J. J. Neurosci. (2003)
- Pore mutation in a G-protein-gated inwardly rectifying K+ channel subunit causes loss of K+-dependent inhibition in weaver hippocampus. Jarolimek, W., Bäurle, J., Misgeld, U. J. Neurosci. (1998)
- D3 dopamine autoreceptors do not activate G-protein-gated inwardly rectifying potassium channel currents in substantia nigra dopamine neurons. Davila, V., Yan, Z., Craciun, L.C., Logothetis, D., Sulzer, D. J. Neurosci. (2003)
- GABA receptors ameliorate Hcy-mediated integrin shedding and constrictive collagen remodeling in microvascular endothelial cells. Shastry, S., Tyagi, N., Moshal, K.S., Lominadze, D., Hayden, M.R., Tyagi, S.C. Cell Biochem. Biophys. (2006)
- Effects of GABAB receptor antagonism on the development of pentylenetetrazol-induced kindling in mice. Getova, D., Froestl, W., Bowery, N.G. Brain Res. (1998)
- Mechanism of colchicine impairment on learning and memory, and protective effect of CGP36742 in mice. Yu, Z., Cheng, G., Hu, B. Brain Res. (1997)
- GABAergic agents modify imipramine analgesia. Ballal, P.M., Mandhane, S.N., Chopde, C.T., Muthal, A.V. Indian J. Physiol. Pharmacol. (1996)