Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

KDM3A - lysine (K)-specific demethylase 3A

Homo sapiens

Synonyms: JHDM2A, JHMD2A, JMJD1, JMJD1A, JmjC domain-containing histone demethylation protein 2A, ...

Knebel, J. et al., Ramos, J.L. et al.

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High impact information on JMJD1A

Although murine TSGA is expressed in testes, its mRNA is also present in many other tissues, including heart, thymus, liver, and skin [1].
Thus, TSGA may modulate the function of ER71 and thereby affect spermatogenesis as well as embryonic development [1].
Furthermore, TSGA impairs the ability of ER71 to activate transcription from the matrix metalloproteinase-1 promoter [1].
Testis-specific gene A (TSGA) was originally identified in rat and shown to be expressed within the testes [1].
The activity of phosphofructokinase was lower in small-for-date term infants (TSGA) and preterm adequate for gestational age (PTAGA) in comparison to term infants adequate for gestational age (TAGA) [2].

References

Repression of transcription by TSGA/Jmjd1a, a novel interaction partner of the ETS protein ER71. Knebel, J., De Haro, L., Janknecht, R. J. Cell. Biochem. (2006)
Red cell enzymes and intermediates in AGA term newborns, AGA preterm newborns and SGA term newborns. Ramos, J.L., Nonoyama, K., Quintal, V.S., Barretto, O.C. Acta paediatrica Scandinavica. (1990)

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KDM3A - lysine (K)-specific demethylase 3A

Homo sapiens

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