Gene Review:
PKN2 - protein kinase N2
Homo sapiens
Synonyms:
PAK2, PKN gamma, PRK2, PRKCL2, PRO2042, ...
- Intra- and intersubtype alternative Pak2-activating structural motifs of human immunodeficiency virus type 1 Nef. O'Neill, E., Baugh, L.L., Novitsky, V.A., Essex, M.E., Garcia, J.V. J. Virol. (2006)
- Effects of overexpression of Pkn2, a transmembrane protein serine/threonine kinase, on development of Myxococcus xanthus. Udo, H., Inouye, M., Inouye, S. J. Bacteriol. (1996)
- Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef. Giese, S.I., Woerz, I., Homann, S., Tibroni, N., Geyer, M., Fackler, O.T. Virology (2006)
- Rho GTPases regulate PRK2/PKN2 to control entry into mitosis and exit from cytokinesis. Schmidt, A., Durgan, J., Magalhaes, A., Hall, A. EMBO J. (2007)
- Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3. Tessier, M., Woodgett, J.R. J. Biol. Chem. (2006)
- The yersinia virulence factor YopM forms a novel protein complex with two cellular kinases. McDonald, C., Vacratsis, P.O., Bliska, J.B., Dixon, J.E. J. Biol. Chem. (2003)
- PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2. Balendran, A., Casamayor, A., Deak, M., Paterson, A., Gaffney, P., Currie, R., Downes, C.P., Alessi, D.R. Curr. Biol. (1999)
- Inhibition of Akt and its anti-apoptotic activities by tumor necrosis factor-induced protein kinase C-related kinase 2 (PRK2) cleavage. Koh, H., Lee, K.H., Kim, D., Kim, S., Kim, J.W., Chung, J. J. Biol. Chem. (2000)
- Mutational analysis of the regulatory mechanism of PKN: the regulatory region of PKN contains an arachidonic acid-sensitive autoinhibitory domain. Yoshinaga, C., Mukai, H., Toshimori, M., Miyamoto, M., Ono, Y. J. Biochem. (1999)
- Molecular characterization of the effects of Y-27632. Darenfed, H., Dayanandan, B., Zhang, T., Hsieh, S.H., Fournier, A.E., Mandato, C.A. Cell Motil. Cytoskeleton (2007)
- Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family. Palmer, R.H., Ridden, J., Parker, P.J. Eur. J. Biochem. (1995)
- Phosphorylation of protein kinase C-related kinase PRK2 during meiotic maturation of starfish oocytes. Stapleton, G., Nguyen, C.P., Lease, K.A., Hille, M.B. Dev. Biol. (1998)
- p21-activated kinase 2 in neutrophils can be regulated by phosphorylation at multiple sites and by a variety of protein phosphatases. Zhan, Q., Ge, Q., Ohira, T., Van Dyke, T., Badwey, J.A. J. Immunol. (2003)
- Localization of p21-activated protein kinase gamma-PAK/Pak2 in the endoplasmic reticulum is required for induction of cytostasis. Huang, Z., Ling, J., Traugh, J.A. J. Biol. Chem. (2003)
- Isolation and characterization of a structural homologue of human PRK2 from rat liver. Distinguishing substrate and lipid activator specificities. Yu, W., Liu, J., Morrice, N.A., Wettenhall, R.E. J. Biol. Chem. (1997)
- The protein kinase C-related kinase PRK2 interacts with the protein tyrosine phosphatase PTP-BL via a novel PDZ domain binding motif. Gross, C., Heumann, R., Erdmann, K.S. FEBS Lett. (2001)
- Protein kinase C-related kinase 2 phosphorylates the protein synthesis initiation factor eIF4E in starfish oocytes. Lee, S.J., Stapleton, G., Greene, J.H., Hille, M.B. Dev. Biol. (2000)
- Multiple interactions of PRK1 with RhoA. Functional assignment of the Hr1 repeat motif. Flynn, P., Mellor, H., Palmer, R., Panayotou, G., Parker, P.J. J. Biol. Chem. (1998)
- A comparative study of post-operative pain in laser epithelial keratomileusis versus photorefractive keratectomy. Saleh, T.A., Almasri, M.A. The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. (2003)