Gene Review:
SULF2 - sulfatase 2
Homo sapiens
Synonyms:
Extracellular sulfatase Sulf-2, HSULF-2, KIAA1247, SULF-2, UNQ559/PRO1120, ...
- Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer. Morimoto-Tomita, M., Uchimura, K., Bistrup, A., Lum, D.H., Egeblad, M., Boudreau, N., Werb, Z., Rosen, S.D. Neoplasia (2005)
- HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo. Dai, Y., Yang, Y., MacLeod, V., Yue, X., Rapraeger, A.C., Shriver, Z., Venkataraman, G., Sasisekharan, R., Sanderson, R.D. J. Biol. Chem. (2005)
- Endosome-to-Golgi transport is regulated by protein kinase A type II alpha. Birkeli, K.A., Llorente, A., Torgersen, M.L., Keryer, G., Taskén, K., Sandvig, K. J. Biol. Chem. (2003)
- Insulin modulates the secretion of proteins from mature 3T3-L1 adipocytes: a role for transcriptional regulation of processing. Wang, P., Keijer, J., Bunschoten, A., Bouwman, F., Renes, J., Mariman, E. Diabetologia (2006)
- Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase. Saad, O.M., Ebel, H., Uchimura, K., Rosen, S.D., Bertozzi, C.R., Leary, J.A. Glycobiology (2005)
- Cloning and characterization of two cDNAs encoding sulfatases in the Roman snail, Helix pomatia. Wittstock, U., Fischer, M., Svendsen, I., Halkier, B.A. IUBMB Life (2000)
- Measuring the activities of the sulfs: two novel heparin/heparan sulfate endosulfatases. Uchimura, K., Morimoto-Tomita, M., Rosen, S.D. Meth. Enzymol. (2006)
- Expression of a heparan sulfate remodeling enzyme, heparan sulfate 6-O-endosulfatase sulfatase FP2, in the rat nervous system. Nagamine, S., Koike, S., Keino-Masu, K., Masu, M. Brain Res. Dev. Brain Res. (2005)
- HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. Uchimura, K., Morimoto-Tomita, M., Bistrup, A., Li, J., Lyon, M., Gallagher, J., Werb, Z., Rosen, S.D. BMC Biochem. (2006)