Gene Review:
TRPV5 - transient receptor potential cation...
Homo sapiens
Synonyms:
CAT2, CaT2, Calcium transport protein 2, ECAC1, ECaC, ...
- The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption. van der Eerden, B.C., Hoenderop, J.G., de Vries, T.J., Schoenmaker, T., Buurman, C.J., Uitterlinden, A.G., Pols, H.A., Bindels, R.J., van Leeuwen, J.P. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Acid-base status determines the renal expression of Ca2+ and Mg2+ transport proteins. Nijenhuis, T., Renkema, K.Y., Hoenderop, J.G., Bindels, R.J. J. Am. Soc. Nephrol. (2006)
- WNK4 enhances TRPV5-mediated calcium transport: potential role in hypercalciuria of familial hyperkalemic hypertension caused by gene mutation of WNK4. Jiang, Y., Ferguson, W.B., Peng, J.B. Am. J. Physiol. Renal Physiol. (2007)
- TRPV5, the gateway to Ca2+ homeostasis. Mensenkamp, A.R., Hoenderop, J.G., Bindels, R.J. Handbook of experimental pharmacology (2007)
- Sensitization to epithelial antigens in chronic mucosal inflammatory disease. Characterization of human intestinal mucosa-derived mononuclear cells reactive with purified epithelial cell-associated components in vitro. Roche, J.K., Fiocchi, C., Youngman, K. J. Clin. Invest. (1985)
- Calcium absorption across epithelia. Hoenderop, J.G., Nilius, B., Bindels, R.J. Physiol. Rev. (2005)
- Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia. Nijenhuis, T., Vallon, V., van der Kemp, A.W., Loffing, J., Hoenderop, J.G., Bindels, R.J. J. Clin. Invest. (2005)
- Expression of immune sensitization to epithelial cell-associated components in the cotton-top tamarin: a model of chronic ulcerative colitis. Winter, H.S., Crum, P.M., King, N.W., Sehgal, P.K., Roche, J.K. Gastroenterology (1989)
- Platonin attenuates LPS-induced CAT-2 and CAT-2B induction in stimulated murine macrophages. Chen, C.C., Lee, J.J., Tsai, P.S., Lu, Y.T., Huang, C.L., Huang, C.J. Acta anaesthesiologica Scandinavica. (2006)
- Intestinal mast cell responses in idiopathic inflammatory bowel disease. Histamine release from human intestinal mast cells in response to gut epithelial proteins. Fox, C.C., Lichtenstein, L.M., Roche, J.K. Dig. Dis. Sci. (1993)
- System y+ arginine transport and NO production in peripheral blood mononuclear cells in pregnancy and preeclampsia. McCord, N., Ayuk, P., McMahon, M., Boyd, R.C., Sargent, I., Redman, C. Hypertension (2006)
- Requirement of PDZ domains for the stimulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase SGK1. Palmada, M., Poppendieck, S., Embark, H.M., van de Graaf, S.F., Boehmer, C., Bindels, R.J., Lang, F. Cell. Physiol. Biochem. (2005)
- Functional characterisation and genomic analysis of an epithelial calcium channel (ECaC) from pufferfish, Fugu rubripes. Qiu, A., Hogstrand, C. Gene (2004)
- Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex. van de Graaf, S.F., Hoenderop, J.G., Gkika, D., Lamers, D., Prenen, J., Rescher, U., Gerke, V., Staub, O., Nilius, B., Bindels, R.J. EMBO J. (2003)
- Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport. Lambers, T.T., Mahieu, F., Oancea, E., Hoofd, L., de Lange, F., Mensenkamp, A.R., Voets, T., Nilius, B., Clapham, D.E., Hoenderop, J.G., Bindels, R.J. EMBO J. (2006)
- Molecular determinants in TRPV5 channel assembly. Chang, Q., Gyftogianni, E., van de Graaf, S.F., Hoefs, S., Weidema, F.A., Bindels, R.J., Hoenderop, J.G. J. Biol. Chem. (2004)
- Diverse Calcium Channel Types are Present in the Human Placental Syncytiotrophoblast Basal Membrane. Bernucci, L., Henríquez, M., Díaz, P., Riquelme, G. Placenta (2006)
- Regulation of the epithelial Ca2+ channels TRPV5 and TRPV6 by 1alpha,25-dihydroxy Vitamin D3 and dietary Ca2+. van de Graaf, S.F., Boullart, I., Hoenderop, J.G., Bindels, R.J. J. Steroid Biochem. Mol. Biol. (2004)
- Immobilization decreases duodenal calcium absorption through a 1,25-dihydroxyvitamin D-dependent pathway. Sato, T., Yamamoto, H., Sawada, N., Nashiki, K., Tsuji, M., Nikawa, T., Arai, H., Morita, K., Taketani, Y., Takeda, E. J. Bone Miner. Metab. (2006)
- Regulation of TRP channels by N-linked glycosylation. Cohen, D.M. Semin. Cell Dev. Biol. (2006)
- The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation. den Dekker, E., Hoenderop, J.G., Nilius, B., Bindels, R.J. Cell Calcium (2003)
- Molecular mechanism of active Ca2+ reabsorption in the distal nephron. Hoenderop, J.G., Nilius, B., Bindels, R.J. Annu. Rev. Physiol. (2002)
- Recent advances in renal tubular calcium reabsorption. Mensenkamp, A.R., Hoenderop, J.G., Bindels, R.J. Curr. Opin. Nephrol. Hypertens. (2006)
- Structural conservation of the genes encoding CaT1, CaT2, and related cation channels. Peng, J.B., Brown, E.M., Hediger, M.A. Genomics (2001)
- The immunophilin FKBP52 inhibits the activity of the epithelial Ca2+ channel TRPV5. Gkika, D., Topala, C.N., Hoenderop, J.G., Bindels, R.J. Am. J. Physiol. Renal Physiol. (2006)
- Ca2+-selective transient receptor potential V channel architecture and function require a specific ankyrin repeat. Erler, I., Hirnet, D., Wissenbach, U., Flockerzi, V., Niemeyer, B.A. J. Biol. Chem. (2004)
- Regulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase isoforms SGK1 and SGK3 expressed in Xenopus oocytes. Embark, H.M., Setiawan, I., Poppendieck, S., van de Graaf, S.F., Boehmer, C., Palmada, M., Wieder, T., Gerstberger, R., Cohen, P., Yun, C.C., Bindels, R.J., Lang, F. Cell. Physiol. Biochem. (2004)
- Pharmacological modulation of monovalent cation currents through the epithelial Ca2+ channel ECaC1. Nilius, B., Prenen, J., Vennekens, R., Hoenderop, J.G., Bindels, R.J., Droogmans, G. Br. J. Pharmacol. (2001)
- Molecular cloning, tissue distribution, and chromosomal mapping of the human epithelial Ca2+ channel (ECAC1). Müller, D., Hoenderop, J.G., Meij, I.C., van den Heuvel, L.P., Knoers, N.V., den Hollander, A.I., Eggert, P., García-Nieto, V., Claverie-Martín, F., Bindels, R.J. Genomics (2000)
- Gene structure and chromosomal mapping of human epithelial calcium channel. Müller, D., Hoenderop, J.G., Merkx, G.F., van Os, C.H., Bindels, R.J. Biochem. Biophys. Res. Commun. (2000)
- Differential regulation of L-arginine transporters (cationic amino acid transporter-1 and -2) by peroxynitrite in rat mesangial cells. Schwartz, I.F., Chernichovsky, T., Hagin, D., Ingbir, M., Reshef, R., Chernin, G., Levo, Y., Schwartz, D. Nephrol. Dial. Transplant. (2006)