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Gene Review

Ly6c  -  Ly6-C antigen

Rattus norvegicus

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High impact information on Ly6c

  • S14 mAb, the specificity of which is confirmed by a cDNA transfectant, recognizes Ly6C antigen preferentially expressed on a part of CD8+ T cells in peripheral lymphoid organs [1].


  1. A T cell activation antigen, Ly6C, induced on CD4+ Th1 cells mediates an inhibitory signal for secretion of IL-2 and proliferation in peripheral immune responses. Yamanouchi, S., Kuwahara, K., Sakata, A., Ezaki, T., Matsuoka, S., Miyazaki, J., Hirose, S., Tamura, T., Nariuchi, H., Sakaguchi, N. Eur. J. Immunol. (1998) [Pubmed]
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