Gene Review:
NDRG2 - NDRG family member 2
Homo sapiens
Synonyms:
KIAA1248, N-myc downstream-regulated gene 2 protein, Protein NDRG2, Protein Syld709613, SYLD
- Integrative genomic analysis identifies NDRG2 as a candidate tumor suppressor gene frequently inactivated in clinically aggressive meningioma. Lusis, E.A., Watson, M.A., Chicoine, M.R., Lyman, M., Roerig, P., Reifenberger, G., Gutmann, D.H., Perry, A. Cancer Res. (2005)
- N-Myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation. Deng, Y., Yao, L., Chau, L., Ng, S.S., Peng, Y., Liu, X., Au, W.S., Wang, J., Li, F., Ji, S., Han, H., Nie, X., Li, Q., Kung, H.F., Leung, S.Y., Lin, M.C. Int. J. Cancer (2003)
- NDRG2 expression and mutation in human liver and pancreatic cancers. Hu, X.L., Liu, X.P., Lin, S.X., Deng, Y.C., Liu, N., Li, X., Yao, L.B. World J. Gastroenterol. (2004)
- NDRG2: a novel Alzheimer's disease associated protein. Mitchelmore, C., Büchmann-Møller, S., Rask, L., West, M.J., Troncoso, J.C., Jensen, N.A. Neurobiol. Dis. (2004)
- The Repression of Human Differentiation-related Gene NDRG2 Expression by Myc via Miz-1-dependent Interaction with the NDRG2 Core Promoter. Zhang, J., Li, F., Liu, X., Shen, L., Liu, J., Su, J., Zhang, W., Deng, Y., Wang, L., Liu, N., Han, W., Zhang, J., Ji, S., Yang, A., Han, H., Yao, L. J. Biol. Chem. (2006)
- Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta. Burchfield, J.G., Lennard, A.J., Narasimhan, S., Hughes, W.E., Wasinger, V.C., Corthals, G.L., Okuda, T., Kondoh, H., Biden, T.J., Schmitz-Peiffer, C. J. Biol. Chem. (2004)
- Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family. Qu, X., Zhai, Y., Wei, H., Zhang, C., Xing, G., Yu, Y., He, F. Mol. Cell. Biochem. (2002)
- Expression and regulation of NDRG2 (N-myc downstream regulated gene 2) during the differentiation of dendritic cells. Choi, S.C., Kim, K.D., Kim, J.T., Kim, J.W., Yoon, D.Y., Choe, Y.K., Chang, Y.S., Paik, S.G., Lim, J.S. FEBS Lett. (2003)
- Characterization of rat NDRG2 (N-Myc downstream regulated gene 2), a novel early mineralocorticoid-specific induced gene. Boulkroun, S., Fay, M., Zennaro, M.C., Escoubet, B., Jaisser, F., Blot-Chabaud, M., Farman, N., Courtois-Coutry, N. J. Biol. Chem. (2002)
- Expression of androgen receptor and androgen regulation of NDRG2 in the rat renal collecting duct. Boulkroun, S., Le Moellic, C., Blot-Chabaud, M., Farman, N., Courtois-Coutry, N. Pflugers Arch. (2005)
- Expression of Ndrg2 in the rat frontal cortex after antidepressant and electroconvulsive treatment. Takahashi, K., Yamada, M., Ohata, H., Momose, K., Higuchi, T., Honda, K., Yamada, M. Int. J. Neuropsychopharmacol. (2005)
- Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. Murray, J.T., Campbell, D.G., Morrice, N., Auld, G.C., Shpiro, N., Marquez, R., Peggie, M., Bain, J., Bloomberg, G.B., Grahammer, F., Lang, F., Wulff, P., Kuhl, D., Cohen, P. Biochem. J. (2004)
- Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart. Zhou, R.H., Kokame, K., Tsukamoto, Y., Yutani, C., Kato, H., Miyata, T. Genomics (2001)
- Ndrg2, a novel gene regulated by adrenal steroids and antidepressants, is highly expressed in astrocytes. Nichols, N.R. Ann. N. Y. Acad. Sci. (2003)