Gene Review:
RAB6A - RAB6A, member RAS oncogene family
Homo sapiens
Synonyms:
RAB6, Rab-6, Ras-related protein Rab-6A
- Rab6c, a new member of the rab gene family, is involved in drug resistance in MCF7/AdrR cells. Shan, J., Mason, J.M., Yuan, L., Barcia, M., Porti, D., Calabro, A., Budman, D., Vinciguerra, V., Xu, H. Gene (2000)
- Characterization of the unprocessed and processed forms of rab6 expressed in baculovirus/insect cell systems. Yang, C., Mayau, V., Godeau, F., Goud, B. Biochem. Biophys. Res. Commun. (1992)
- Small GTP-binding protein associated with Golgi cisternae. Goud, B., Zahraoui, A., Tavitian, A., Saraste, J. Nature (1990)
- Golgins in the structure and dynamics of the Golgi apparatus. Barr, F.A., Short, B. Curr. Opin. Cell Biol. (2003)
- Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Matanis, T., Akhmanova, A., Wulf, P., Del Nery, E., Weide, T., Stepanova, T., Galjart, N., Grosveld, F., Goud, B., De Zeeuw, C.I., Barnekow, A., Hoogenraad, C.C. Nat. Cell Biol. (2002)
- Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum. Girod, A., Storrie, B., Simpson, J.C., Johannes, L., Goud, B., Roberts, L.M., Lord, J.M., Nilsson, T., Pepperkok, R. Nat. Cell Biol. (1999)
- Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases. Hyvola, N., Diao, A., McKenzie, E., Skippen, A., Cockcroft, S., Lowe, M. EMBO J. (2006)
- Identification of small GTP-binding rab proteins in human platelets: thrombin-induced phosphorylation of rab3B, rab6, and rab8 proteins. Karniguian, A., Zahraoui, A., Tavitian, A. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Determination of structural requirements for the interaction of Rab6 with RabGDI and Rab geranylgeranyltransferase. Beranger, F., Cadwallader, K., Porfiri, E., Powers, S., Evans, T., de Gunzburg, J., Hancock, J.F. J. Biol. Chem. (1994)
- Regulation of microtubule-dependent recycling at the trans-Golgi network by Rab6A and Rab6A'. Young, J., Stauber, T., del Nery, E., Vernos, I., Pepperkok, R., Nilsson, T. Mol. Biol. Cell (2005)
- Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms. Echard, A., Opdam, F.J., de Leeuw, H.J., Jollivet, F., Savelkoul, P., Hendriks, W., Voorberg, J., Goud, B., Fransen, J.A. Mol. Biol. Cell (2000)
- A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint. Miserey-Lenkei, S., Couëdel-Courteille, A., Del Nery, E., Bardin, S., Piel, M., Racine, V., Sibarita, J.B., Perez, F., Bornens, M., Goud, B. EMBO J. (2006)
- Distinct structural elements of rab5 define its functional specificity. Stenmark, H., Valencia, A., Martinez, O., Ullrich, O., Goud, B., Zerial, M. EMBO J. (1994)
- Recombinant antibodies to the small GTPase Rab6 as conformation sensors. Nizak, C., Monier, S., del Nery, E., Moutel, S., Goud, B., Perez, F. Science (2003)
- GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex. Tisdale, E.J., Bourne, J.R., Khosravi-Far, R., Der, C.J., Balch, W.E. J. Cell Biol. (1992)
- GTP-bound forms of rab6 induce the redistribution of Golgi proteins into the endoplasmic reticulum. Martinez, O., Antony, C., Pehau-Arnaudet, G., Berger, E.G., Salamero, J., Goud, B. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Rab6 is associated with a compartment that transports rhodopsin from the trans-Golgi to the site of rod outer segment disk formation in frog retinal photoreceptors. Deretic, D., Papermaster, D.S. J. Cell. Sci. (1993)
- Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome. Cuif, M.H., Possmayer, F., Zander, H., Bordes, N., Jollivet, F., Couedel-Courteille, A., Janoueix-Lerosey, I., Langsley, G., Bornens, M., Goud, B. EMBO J. (1999)
- REP-2, a Rab escort protein encoded by the choroideremia-like gene. Cremers, F.P., Armstrong, S.A., Seabra, M.C., Brown, M.S., Goldstein, J.L. J. Biol. Chem. (1994)
- Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER. Valsdottir, R., Hashimoto, H., Ashman, K., Koda, T., Storrie, B., Nilsson, T. FEBS Lett. (2001)
- The Rab6-binding kinesin, Rab6-KIFL, is required for cytokinesis. Hill, E., Clarke, M., Barr, F.A. EMBO J. (2000)
- WTH3, a new member of the Rab6 gene family, and multidrug resistance. Shan, J., Yuan, L., Budman, D.R., Xu, H.P. Biochim. Biophys. Acta (2002)
- The small GTP-binding protein rab6p is distributed from medial Golgi to the trans-Golgi network as determined by a confocal microscopic approach. Antony, C., Cibert, C., Géraud, G., Santa Maria, A., Maro, B., Mayau, V., Goud, B. J. Cell. Sci. (1992)
- Several small GTP-binding proteins are strongly down-regulated in simian virus 40 (SV40) transformed human keratinocytes and may be required for the maintenance of the normal phenotype. Gromov, P.S., Celis, J.E. Electrophoresis (1994)
- Association of the calpain/calpastatin network with subcellular organelles. Hood, J.L., Logan, B.B., Sinai, A.P., Brooks, W.H., Roszman, T.L. Biochem. Biophys. Res. Commun. (2003)