Gene Review:
RAD51B - RAD51 paralog B
Homo sapiens
Synonyms:
DNA repair protein RAD51 homolog 2, R51H2, RAD51 homolog B, RAD51-like protein 1, RAD51L1, ...
- Haploinsufficiency of RAD51B causes centrosome fragmentation and aneuploidy in human cells. Date, O., Katsura, M., Ishida, M., Yoshihara, T., Kinomura, A., Sueda, T., Miyagawa, K. Cancer Res. (2006)
- Familial occurrence of thymoma and autoimmune diseases with the constitutional translocation t(14;20)(q24.1;p12.3). Nicodème, F., Geffroy, S., Conti, M., Delobel, B., Soenen, V., Grardel, N., Porte, H., Copin, M.C., Laï, J.L., Andrieux, J. Genes Chromosomes Cancer (2005)
- A surfeit of RAD51-like genes? Thacker, J. Trends Genet. (1999)
- The Rad51 paralog Rad51B promotes homologous recombinational repair. Takata, M., Sasaki, M.S., Sonoda, E., Fukushima, T., Morrison, C., Albala, J.S., Swagemakers, S.M., Kanaar, R., Thompson, L.H., Takeda, S. Mol. Cell. Biol. (2000)
- The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells. Zeidler, M., Varambally, S., Cao, Q., Chinnaiyan, A.M., Ferguson, D.O., Merajver, S.D., Kleer, C.G. Neoplasia (2005)
- Evidence for RAD51L1/HMGIC fusion in the pathogenesis of uterine leiomyoma. Takahashi, T., Nagai, N., Oda, H., Ohama, K., Kamada, N., Miyagawa, K. Genes Chromosomes Cancer (2001)
- The human REC2/RAD51B gene acts as a DNA damage sensor by inducing G1 delay and hypersensitivity to ultraviolet irradiation. Havre, P.A., Rice, M.C., Noe, M., Kmiec, E.B. Cancer Res. (1998)
- Allelic knockout of novel splice variants of human recombination repair gene RAD51B in t(12;14) uterine leiomyomas. Schoenmakers, E.F., Huysmans, C., Van de Ven, W.J. Cancer Res. (1999)
- XRCC3 ATPase activity is required for normal XRCC3-Rad51C complex dynamics and homologous recombination. Yamada, N.A., Hinz, J.M., Kopf, V.L., Segalle, K.D., Thompson, L.H. J. Biol. Chem. (2004)
- Identification of a novel human RAD51 homolog, RAD51B. Albala, J.S., Thelen, M.P., Prange, C., Fan, W., Christensen, M., Thompson, L.H., Lennon, G.G. Genomics (1997)
- hREC2, a RAD51-like gene, is disrupted by t(12;14) (q15;q24.1) in a uterine leiomyoma. Ingraham, S.E., Lynch, R.A., Kathiresan, S., Buckler, A.J., Menon, A.G. Cancer Genet. Cytogenet. (1999)
- Holliday junction binding activity of the human Rad51B protein. Yokoyama, H., Kurumizaka, H., Ikawa, S., Yokoyama, S., Shibata, T. J. Biol. Chem. (2003)
- RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51. Miller, K.A., Yoshikawa, D.M., McConnell, I.R., Clark, R., Schild, D., Albala, J.S. J. Biol. Chem. (2002)
- Evidence for simultaneous protein interactions between human Rad51 paralogs. Schild, D., Lio, Y.C., Collins, D.W., Tsomondo, T., Chen, D.J. J. Biol. Chem. (2000)
- Fusion transcripts involving HMGA2 are not a common molecular mechanism in uterine leiomyomata with rearrangements in 12q15. Quade, B.J., Weremowicz, S., Neskey, D.M., Vanni, R., Ladd, C., Dal Cin, P., Morton, C.C. Cancer Res. (2003)
- Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells. Wiese, C., Collins, D.W., Albala, J.S., Thompson, L.H., Kronenberg, A., Schild, D. Nucleic Acids Res. (2002)
- Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells. Liu, N., Schild, D., Thelen, M.P., Thompson, L.H. Nucleic Acids Res. (2002)
- Nuclear localization of Rad51B is independent of Rad51C and BRCA2. Miller, K.A., Hinz, J.M., Yamada, N.A., Thompson, L.H., Albala, J.S. Mutagenesis (2005)
- Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis. Rice, M.C., Smith, S.T., Bullrich, F., Havre, P., Kmiec, E.B. Proc. Natl. Acad. Sci. U.S.A. (1997)