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Gene Review

PRDM12  -  PR domain containing 12

Homo sapiens

Synonyms: PFM9, PR domain zinc finger protein 12, PR domain-containing protein 12
 
 
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High impact information on PRDM12

  • A potential role for PRDM12 in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion [1].
  • Of the four ESTs and/or genes that map to the 120 kb region, the putative tumor suppressor PRDM12 is the strongest candidate gene [2].

References

  1. A potential role for PRDM12 in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion. Reid, A.G., Nacheva, E.P. Leukemia (2004) [Pubmed]
  2. Quantitative PCR identifies a minimal deleted region of 120 kb extending from the Philadelphia chromosome ABL translocation breakpoint in chronic myeloid leukemia with poor outcome. Kolomietz, E., Marrano, P., Yee, K., Thai, B., Braude, I., Kolomietz, A., Chun, K., Minkin, S., Kamel-Reid, S., Minden, M., Squire, J.A. Leukemia (2003) [Pubmed]
 
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