Gene Review:
BACH2 - BTB and CNC homology 1, basic leucine...
Homo sapiens
Synonyms:
BTB and CNC homolog 2, BTBD25, Transcription regulator protein BACH2
- B-cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs. Kamio, T., Toki, T., Kanezaki, R., Sasaki, S., Tandai, S., Terui, K., Ikebe, D., Igarashi, K., Ito, E. Blood (2003)
- Prognostic significance of BACH2 expression in diffuse large B-cell lymphoma: a study of the Osaka Lymphoma Study Group. Sakane-Ishikawa, E., Nakatsuka, S., Tomita, Y., Fujita, S., Nakamichi, I., Takakuwa, T., Sugiyama, H., Fukuhara, S., Hino, M., Kanamaru, A., Soma, T., Tsukaguchi, M., Igarashi, K., Kanakura, Y., Aozasa, K. J. Clin. Oncol. (2005)
- Integration of Epstein-Barr virus into chromosome 6q15 of Burkitt lymphoma cell line (Raji) induces loss of BACH2 expression. Takakuwa, T., Luo, W.J., Ham, M.F., Sakane-Ishikawa, F., Wada, N., Aozasa, K. Am. J. Pathol. (2004)
- Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer. Muto, A., Hoshino, H., Madisen, L., Yanai, N., Obinata, M., Karasuyama, H., Hayashi, N., Nakauchi, H., Yamamoto, M., Groudine, M., Igarashi, K. EMBO J. (1998)
- Bcr-Abl signaling through the PI-3/S6 kinase pathway inhibits nuclear translocation of the transcription factor Bach2, which represses the antiapoptotic factor heme oxygenase-1. Yoshida, C., Yoshida, F., Sears, D.E., Hart, S.M., Ikebe, D., Muto, A., Basu, S., Igarashi, K., Melo, J.V. Blood (2007)
- Differentially androgen-modulated genes in ovarian epithelial cells from BRCA mutation carriers and control patients predict ovarian cancer survival and disease progression. Motamed-Khorasani, A., Jurisica, I., Letarte, M., Shaw, P.A., Parkes, R.K., Zhang, X., Evangelou, A., Rosen, B., Murphy, K.J., Brown, T.J. Oncogene (2007)
- Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15. Sasaki, S., Ito, E., Toki, T., Maekawa, T., Kanezaki, R., Umenai, T., Muto, A., Nagai, H., Kinoshita, T., Yamamoto, M., Inazawa, J., Taketo, M.M., Nakahata, T., Igarashi, K., Yokoyama, M. Oncogene (2000)
- Transcription factor BACH2 is transcriptionally regulated by the BCR/ABL oncogene. Vieira, S.A., Deininger, M.W., Sorour, A., Sinclair, P., Foroni, L., Goldman, J.M., Melo, J.V. Genes Chromosomes Cancer (2001)
- Recurrent HIV-1 Integration at the BACH2 Locus in Resting CD4+ T Cell Populations during Effective Highly Active Antiretroviral Therapy. Ikeda, T., Shibata, J., Yoshimura, K., Koito, A., Matsushita, S. J. Infect. Dis. (2007)
- Nuclear positioning of the BACH2 gene in BCR-ABL positive leukemic cells. Ono, A., Kono, K., Ikebe, D., Muto, A., Sun, J., Kobayashi, M., Ueda, K., Melo, J.V., Igarashi, K., Tashiro, S. Genes Chromosomes Cancer (2007)
- Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Oyake, T., Itoh, K., Motohashi, H., Hayashi, N., Hoshino, H., Nishizawa, M., Yamamoto, M., Igarashi, K. Mol. Cell. Biol. (1996)
- Cadmium induces nuclear export of Bach1, a transcriptional repressor of heme oxygenase-1 gene. Suzuki, H., Tashiro, S., Sun, J., Doi, H., Satomi, S., Igarashi, K. J. Biol. Chem. (2003)