Gene Review:
Lif - leukemia inhibitory factor
Rattus norvegicus
Synonyms:
Cholinergic neuronal differentiation factor, LIF, Leukemia inhibitory factor
- DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor. Blanchard, F., Tracy, E., Smith, J., Chattopadhyay, S., Wang, Y., Held, W.A., Baumann, H. Hepatology (2003)
- A sweat gland-derived differentiation activity acts through known cytokine signaling pathways. Habecker, B.A., Symes, A.J., Stahl, N., Francis, N.J., Economides, A., Fink, J.S., Yancopoulos, G.D., Landis, S.C. J. Biol. Chem. (1997)
- Leukemia inhibitory factor is involved in tubular regeneration after experimental acute renal failure. Yoshino, J., Monkawa, T., Tsuji, M., Hayashi, M., Saruta, T. J. Am. Soc. Nephrol. (2003)
- Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats. Suzuki, S., Yamashita, T., Tanaka, K., Hattori, H., Sawamoto, K., Okano, H., Suzuki, N. J. Cereb. Blood Flow Metab. (2005)
- Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats. Watanabe, Y., Hashimoto, S., Kakita, A., Takahashi, H., Ko, J., Mizuno, M., Someya, T., Patterson, P.H., Nawa, H. Neurosci. Res. (2004)
- Leukemia inhibitory factor (LIF) stimulates proopiomelanocortin (POMC) expression in a corticotroph cell line. Role of STAT pathway. Ray, D.W., Ren, S.G., Melmed, S. J. Clin. Invest. (1996)
- Postnatal development of survival responsiveness in rat sympathetic neurons to leukemia inhibitory factor and ciliary neurotrophic factor. Kotzbauer, P.T., Lampe, P.A., Estus, S., Milbrandt, J., Johnson, E.M. Neuron (1994)
- Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve. Curtis, R., Scherer, S.S., Somogyi, R., Adryan, K.M., Ip, N.Y., Zhu, Y., Lindsay, R.M., DiStefano, P.S. Neuron (1994)
- LIF and CNTF, which share the gp130 transduction system, stimulate hepatic lipid metabolism in rats. Nonogaki, K., Pan, X.M., Moser, A.H., Shigenaga, J., Staprans, I., Sakamoto, N., Grunfeld, C., Feingold, K.R. Am. J. Physiol. (1996)
- Leukemia inhibitory factor regulates prolactin secretion in prolactinoma and lactotroph cells. Ben-Shlomo, A., Miklovsky, I., Ren, S.G., Yong, W.H., Heaney, A.P., Culler, M.D., Melmed, S. J. Clin. Endocrinol. Metab. (2003)
- Differential expression of M-CSF, LIF, and TNF-alpha genes in normal and malignant rat glial cells: regulation by lipopolysaccharide and vitamin D. Furman, I., Baudet, C., Brachet, P. J. Neurosci. Res. (1996)
- Leukemia inhibitory factor and ciliary neurotrophic factor cause dendritic retraction in cultured rat sympathetic neurons. Guo, X., Chandrasekaran, V., Lein, P., Kaplan, P.L., Higgins, D. J. Neurosci. (1999)
- Leukemia inhibitory factor and neurotrophins support overlapping populations of rat nodose sensory neurons in culture. Thaler, C.D., Suhr, L., Ip, N., Katz, D.M. Dev. Biol. (1994)
- Expression of leukemia inhibitory factor (LIF)/interleukin-6 family cytokines and receptors during in vitro osteogenesis: differential regulation by dexamethasone and LIF. Liu, F., Aubin, J.E., Malaval, L. Bone (2002)
- Spatiotemporal distribution of gp130 cytokines and their receptors after status epilepticus: comparison with neuronal degeneration and microglial activation. Rosell, D.R., Nacher, J., Akama, K.T., McEwen, B.S. Neuroscience (2003)
- Developmental stage-dependent self-regulation of embryonic cortical precursor cell survival and differentiation by leukemia inhibitory factor. Chang, M.Y., Park, C.H., Son, H., Lee, Y.S., Lee, S.H. Cell Death Differ. (2004)
- mRNAs encoding muscarinic and substance P receptors in cultured sympathetic neurons are differentially regulated by LIF or CNTF. Ludlam, W.H., Zang, Z., McCarson, K.E., Krause, J.E., Spray, D.C., Kessler, J.A. Dev. Biol. (1994)
- Leukemia inhibitory factor and ciliary neurotrophic factor increase activated Ras in a neuroblastoma cell line and in sympathetic neuron cultures. Schwarzschild, M.A., Dauer, W.T., Lewis, S.E., Hamill, L.K., Fink, J.S., Hyman, S.E. J. Neurochem. (1994)
- Expression of leukemia inhibitory factor and its receptor during liver regeneration in the adult rat. Omori, N., Evarts, R.P., Omori, M., Hu, Z., Marsden, E.R., Thorgeirsson, S.S. Lab. Invest. (1996)
- Kainic acid induces leukemia inhibitory factor mRNA expression in the rat brain: differences in the time course of mRNA expression between the dentate gyrus and hippocampal CA1/CA3 subfields. Minami, M., Maekawa, K., Yamakuni, H., Katayama, T., Nakamura, J., Satoh, M. Brain Res. Mol. Brain Res. (2002)
- Leukemia inhibitory factor activates cardiac L-Type Ca2+ channels via phosphorylation of serine 1829 in the rabbit Cav1.2 subunit. Takahashi, E., Fukuda, K., Miyoshi, S., Murata, M., Kato, T., Ita, M., Tanabe, T., Ogawa, S. Circ. Res. (2004)
- LIF, but not IL-6, regulates osteoprogenitor differentiation in rat calvaria cell cultures: modulation by dexamethasone. Malaval, L., Gupta, A.K., Liu, F., Delmas, P.D., Aubin, J.E. J. Bone Miner. Res. (1998)
- Cytokine G-protein signaling crosstalk in cardiomyocytes: attenuation of Jak-STAT activation by endothelin-1. Booz, G.W., Day, J.N., Speth, R., Baker, K.M. Mol. Cell. Biochem. (2002)
- Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes. Kunisada, K., Hirota, H., Fujio, Y., Matsui, H., Tani, Y., Yamauchi-Takihara, K., Kishimoto, T. Circulation (1996)
- Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction. Negoro, S., Oh, H., Tone, E., Kunisada, K., Fujio, Y., Walsh, K., Kishimoto, T., Yamauchi-Takihara, K. Circulation (2001)
- Increased expression of IL-6 and LIF in the hypertrophied left ventricle of TGR(mRen2)27 and SHR rats. Kurdi, M., Randon, J., Cerutti, C., Bricca, G. Mol. Cell. Biochem. (2005)
- Promotion of the development of enteric neurons and glia by neuropoietic cytokines: interactions with neurotrophin-3. Chalazonitis, A., Rothman, T.P., Chen, J., Vinson, E.N., MacLennan, A.J., Gershon, M.D. Dev. Biol. (1998)
- Leukemia inhibitory factor induces sympathetic sprouting in intact dorsal root ganglia in the adult rat in vivo. Thompson, S.W., Majithia, A.A. J. Physiol. (Lond.) (1998)
- Cytokine-induced expression of leukemia inhibitory factor in renal mesangial cells. Hartner, A., Sterzel, R.B., Reindl, N., Hocke, G.M., Fey, G.H., Goppelt-Struebe, M. Kidney Int. (1994)