Gene Review:
ROCK1 - Rho-associated, coiled-coil containing...
Homo sapiens
Synonyms:
P160ROCK, ROCK-I, Renal carcinoma antigen NY-REN-35, Rho-associated protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1, ...
- Identification of genes responsible for cell migration by a library of randomized ribozymes. Suyama, E., Kawasaki, H., Kasaoka, T., Taira, K. Cancer Res. (2003)
- Prognostic Significance of Nuclear Factor-{kappa}B p105/p50 in Human Melanoma and Its Role in Cell Migration. Gao, K., Dai, D.L., Martinka, M., Li, G. Cancer Res. (2006)
- Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis. Chang, J., Xie, M., Shah, V.R., Schneider, M.D., Entman, M.L., Wei, L., Schwartz, R.J. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Expression of ROCK-1 in human pancreatic cancer: its down-regulation by morpholino oligo antisense can reduce the migration of pancreatic cancer cells in vitro. Kaneko, K., Satoh, K., Masamune, A., Satoh, A., Shimosegawa, T. Pancreas (2002)
- Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho. Zhou, Y., Su, Y., Li, B., Liu, F., Ryder, J.W., Wu, X., Gonzalez-DeWhitt, P.A., Gelfanova, V., Hale, J.E., May, P.C., Paul, S.M., Ni, B. Science (2003)
- Pharmacy teaching for family practice residents. Kahn, R.F., Spadaro, D.C., Price, R.D. Family medicine. (1985)
- A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor. Pollitt, S.K., Pallos, J., Shao, J., Desai, U.A., Ma, A.A., Thompson, L.M., Marsh, J.L., Diamond, M.I. Neuron (2003)
- PSGL-1 and mTOR regulate translation of ROCK-1 and physiological functions of macrophages. Fox, R., Nhan, T.Q., Law, G.L., Morris, D.R., Liles, W.C., Schwartz, S.M. EMBO J. (2007)
- Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes. Barreiro, O., Yanez-Mo, M., Serrador, J.M., Montoya, M.C., Vicente-Manzanares, M., Tejedor, R., Furthmayr, H., Sanchez-Madrid, F. J. Cell Biol. (2002)
- Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho-associated protein kinase inhibitor Y-27632. Takamura, M., Sakamoto, M., Genda, T., Ichida, T., Asakura, H., Hirohashi, S. Hepatology (2001)
- Exercise-associated hyponatremia in marathon runners: a two-year experience. Davis, D.P., Videen, J.S., Marino, A., Vilke, G.M., Dunford, J.V., Van Camp, S.P., Maharam, L.G. The Journal of emergency medicine. (2001)
- Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK. Pedrini, S., Carter, T.L., Prendergast, G., Petanceska, S., Ehrlich, M.E., Gandy, S. PLoS Med. (2005)
- Cell adhesion status-dependent histone acetylation is regulated through intracellular contractility-related signaling activities. Kim, Y.B., Yu, J., Lee, S.Y., Lee, M.S., Ko, S.G., Ye, S.K., Jong, H.S., Kim, T.Y., Bang, Y.J., Lee, J.W. J. Biol. Chem. (2005)
- Segmental duplication associated with the human-specific inversion of chromosome 18: a further example of the impact of segmental duplications on karyotype and genome evolution in primates. Goidts, V., Szamalek, J.M., Hameister, H., Kehrer-Sawatzki, H. Hum. Genet. (2004)
- The Rho-associated protein kinase p160ROCK is required for centrosome positioning. Chevrier, V., Piel, M., Collomb, N., Saoudi, Y., Frank, R., Paintrand, M., Narumiya, S., Bornens, M., Job, D. J. Cell Biol. (2002)
- Regulation of SOX9 mRNA in Human Articular Chondrocytes Involving p38 MAPK Activation and mRNA Stabilization. Tew, S.R., Hardingham, T.E. J. Biol. Chem. (2006)
- Selective glucocorticoid control of Rho kinase isoforms regulate cell-cell interactions. Rubenstein, N.M., Callahan, J.A., Lo, D.H., Firestone, G.L. Biochem. Biophys. Res. Commun. (2007)
- RhoA is required for monocyte tail retraction during transendothelial migration. Worthylake, R.A., Lemoine, S., Watson, J.M., Burridge, K. J. Cell Biol. (2001)
- Polyamines regulate Rho-kinase and myosin phosphorylation during intestinal epithelial restitution. Rao, J.N., Guo, X., Liu, L., Zou, T., Murthy, K.S., Yuan, J.X., Wang, J.Y. Am. J. Physiol., Cell Physiol. (2003)
- A role for small GTPase RhoA in regulating intracellular membrane traffic of lysosomes in invasive rat hepatoma cells. Nishimura, Y., Itoh, K., Yoshioka, K., Ikeda, K., Himeno, M. Histochem. J. (2002)
- The small GTPase Rho: cellular functions and signal transduction. Narumiya, S. J. Biochem. (1996)
- Caveolin-1 and Lipid Rafts in Confluent BeWo Trophoblasts: Evidence for Rock-1 Association with Caveolin-1. Rashid-Doubell, F., Tannetta, D., Redman, C.W., Sargent, I.L., Boyd, C.A., Linton, E.A. Placenta (2007)
- Expression of BRG1, a human SWI/SNF component, affects the organisation of actin filaments through the RhoA signalling pathway. Asp, P., Wihlborg, M., Karlén, M., Farrants, A.K. J. Cell. Sci. (2002)
- Rho family-associated kinases PAK1 and rock. Maruta, H., Nheu, T.V., He, H., Hirokawa, Y. Progress in cell cycle research. (2003)
- Sodium-hydrogen exchange and platelet function. Rosskopf, D. J. Thromb. Thrombolysis (1999)
- Low density lipoprotein induces eNOS translocation to membrane caveolae: the role of RhoA activation and stress fiber formation. Zhu, Y., Liao, H.L., Niu, X.L., Yuan, Y., Lin, T., Verna, L., Stemerman, M.B. Biochim. Biophys. Acta (2003)
- Physiological role of ROCKs in the cardiovascular system. Noma, K., Oyama, N., Liao, J.K. Am. J. Physiol., Cell Physiol. (2006)
- Pregnancy-induced modulation of calcium mobilization and down-regulation of Rho-kinase expression contribute to attenuated vasopressin-induced contraction of the rat aorta. Katoue, M.G., Khan, I., Oriowo, M.A. Vascul. Pharmacol. (2006)
- Occurrence of dispensing errors and efforts to reduce medication errors at the Central Arkansas Veteran's Healthcare System. Rolland, P. Drug safety : an international journal of medical toxicology and drug experience. (2004)
- Antibodies reactive to Rickettsia rickettsii among children living in the southeast and south central regions of the United States. Marshall, G.S., Stout, G.G., Jacobs, R.F., Schutze, G.E., Paxton, H., Buckingham, S.C., DeVincenzo, J.P., Jackson, M.A., San Joaquin, V.H., Standaert, S.M., Woods, C.R. Archives of pediatrics & adolescent medicine. (2003)