Gene Review:
RORC - RAR-related orphan receptor C
Homo sapiens
Synonyms:
NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, RORG, ...
- Randomized comparison of tamoxifen and two separate doses of toremifene in postmenopausal patients with metastatic breast cancer. Hayes, D.F., Van Zyl, J.A., Hacking, A., Goedhals, L., Bezwoda, W.R., Mailliard, J.A., Jones, S.E., Vogel, C.L., Berris, R.F., Shemano, I. J. Clin. Oncol. (1995)
- Isolation of genes mediating resistance to inhibitors of nucleoside and ergosterol metabolism in Leishmania by overexpression/selection. Cotrim, P.C., Garrity, L.K., Beverley, S.M. J. Biol. Chem. (1999)
- Stress and mTORture signaling. Reiling, J.H., Sabatini, D.M. Oncogene (2006)
- Investigation of the chromosome 17q25 PSORS2 locus in atopic dermatitis. Morar, N., Bowcock, A.M., Harper, J.I., Cookson, W.O., Moffatt, M.F. J. Invest. Dermatol. (2006)
- TOR, a central controller of cell growth. Schmelzle, T., Hall, M.N. Cell (2000)
- Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways. Levine, A.J., Feng, Z., Mak, T.W., You, H., Jin, S. Genes Dev. (2006)
- The TOR signaling cascade regulates gene expression in response to nutrients. Cardenas, M.E., Cutler, N.S., Lorenz, M.C., Di Como, C.J., Heitman, J. Genes Dev. (1999)
- Molecular screening and association studies of retinoid-related orphan receptor gamma (RORC): a positional and functional candidate for type 2 diabetes. Wang, H., Chu, W., Das, S.K., Zheng, Z., Hasstedt, S.J., Elbein, S.C. Mol. Genet. Metab. (2003)
- Schizosaccharomyces pombe AGC family kinase Gad8p forms a conserved signaling module with TOR and PDK1-like kinases. Matsuo, T., Kubo, Y., Watanabe, Y., Yamamoto, M. EMBO J. (2003)
- Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast. Alarcon, C.M., Heitman, J., Cardenas, M.E. Mol. Biol. Cell (1999)
- Rare cancer-specific mutations in PIK3CA show gain of function. Gymnopoulos, M., Elsliger, M.A., Vogt, P.K. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Rapamycin blocks sexual development in fission yeast through inhibition of the cellular function of an FKBP12 homolog. Weisman, R., Finkelstein, S., Choder, M. J. Biol. Chem. (2001)
- Cell growth control: little eukaryotes make big contributions. De Virgilio, C., Loewith, R. Oncogene (2006)
- Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue. Stan, R., McLaughlin, M.M., Cafferkey, R., Johnson, R.K., Rosenberg, M., Livi, G.P. J. Biol. Chem. (1994)
- The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif. Nojima, H., Tokunaga, C., Eguchi, S., Oshiro, N., Hidayat, S., Yoshino, K., Hara, K., Tanaka, N., Avruch, J., Yonezawa, K. J. Biol. Chem. (2003)
- Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: a novel approach for tailored immunosuppressive therapy. Hartmann, B., Schmid, G., Graeb, C., Bruns, C.J., Fischereder, M., Jauch, K.W., Heeschen, C., Guba, M. Kidney Int. (2005)
- Nutrient signaling through TOR kinases controls gene expression and cellular differentiation in fungi. Rohde, J.R., Cardenas, M.E. Curr. Top. Microbiol. Immunol. (2004)
- TOR inhibitors and cardiac allograft vasculopathy: is inhibition of intimal thickening an adequate surrogate of benefit? Mehra, M.R., Uber, P.A. J. Heart Lung Transplant. (2003)
- TOR of the cell cycle: Are there important implications for diabetics in the era of the drug-eluting stent? Carter, A.J. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. (2004)
- Fat metabolism and its response to infusion of insulin and glucose in patients with advanced chronic obstructive pulmonary disease. Jakobsson, P., Jorfeldt, L., von Schenck, H. Clinical physiology (Oxford, England) (1995)