Gene Review:
CEACAM1 - carcinoembryonic antigen-related cell...
Homo sapiens
Synonyms:
BGP, BGP-1, BGP1, BGPI, Biliary glycoprotein 1, ...
- cis-Determinants in the cytoplasmic domain of CEACAM1 responsible for its tumor inhibitory function. Izzi, L., Turbide, C., Houde, C., Kunath, T., Beauchemin, N. Oncogene (1999)
- Neisseria gonorrhoeae kills carcinoembryonic antigen-related cellular adhesion molecule 1 (CD66a)-expressing human B cells and inhibits antibody production. Pantelic, M., Kim, Y.J., Bolland, S., Chen, I., Shively, J., Chen, T. Infect. Immun. (2005)
- Expression pattern of the adhesion molecule CEACAM1 (C-CAM, CD66a, BGP) in gestational trophoblastic lesions. Bamberger, A.M., Sudahl, S., Wagener, C., Löning, T. Int. J. Gynecol. Pathol. (2001)
- Down-regulation of carcinoembryonic antigen family member 2 expression is an early event in colorectal tumorigenesis. Thompson, J., Seitz, M., Chastre, E., Ditter, M., Aldrian, C., Gespach, C., Zimmermann, W. Cancer Res. (1997)
- The carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cells. Huber, M., Izzi, L., Grondin, P., Houde, C., Kunath, T., Veillette, A., Beauchemin, N. J. Biol. Chem. (1999)
- Cell- and region-specific expression of biliary glycoprotein and its messenger RNA in normal human colonic mucosa. Frängsmyr, L., Baranov, V., Prall, F., Yeung, M.M., Wagener, C., Hammarström, S. Cancer Res. (1995)
- Efficacy of xantinolnicotinate in patients with dementia. Kanowski, S., Fischhof, P.K., Grobe-Einsler, R., Wagner, G., Litschauer, G. Pharmacopsychiatry (1990)
- CEACAMs: their role in physiology and pathophysiology. Kuespert, K., Pils, S., Hauck, C.R. Curr. Opin. Cell Biol. (2006)
- SHP1 Phosphatase-Dependent T Cell Inhibition by CEACAM1 Adhesion Molecule Isoforms. Nagaishi, T., Pao, L., Lin, S.H., Iijima, H., Kaser, A., Qiao, S.W., Chen, Z., Glickman, J., Najjar, S.M., Nakajima, A., Neel, B.G., Blumberg, R.S. Immunity (2006)
- CEA-related cell adhesion molecule 1: a potent angiogenic factor and a major effector of vascular endothelial growth factor. Ergün, S., Kilik, N., Ziegeler, G., Hansen, A., Nollau, P., Götze, J., Wurmbach, J.H., Horst, A., Weil, J., Fernando, M., Wagener, C. Mol. Cell (2000)
- CEACAM1 in Cervical Cancer and Precursor Lesions: Association With Human Papillomavirus Infection. Albarran-Somoza, B., Franco-Topete, R., Delgado-Rizo, V., Cerda-Camacho, F., Acosta-Jimenez, L., Lopez-Botet, M., Daneri-Navarro, A. J. Histochem. Cytochem. (2006)
- Retinoic acid treated HL60 cells express CEACAM1 (CD66a) and phagocytose Neisseria gonorrhoeae. Pantelic, M., Chen, I., Parker, J., Zhang, P., Grunert, F., Chen, T. FEMS Immunol. Med. Microbiol. (2004)
- Expression of CEACAM1 in adenocarcinoma of the lung: a factor of independent prognostic significance. Laack, E., Nikbakht, H., Peters, A., Kugler, C., Jasiewicz, Y., Edler, L., Brümmer, J., Schumacher, U., Hossfeld, D.K. J. Clin. Oncol. (2002)
- CEACAM1 enhances invasion and migration of melanocytic and melanoma cells. Ebrahimnejad, A., Streichert, T., Nollau, P., Horst, A.K., Wagener, C., Bamberger, A.M., Brümmer, J. Am. J. Pathol. (2004)
- Activation-induced expression of carcinoembryonic antigen-cell adhesion molecule 1 regulates mouse T lymphocyte function. Nakajima, A., Iijima, H., Neurath, M.F., Nagaishi, T., Nieuwenhuis, E.E., Raychowdhury, R., Glickman, J., Blau, D.M., Russell, S., Holmes, K.V., Blumberg, R.S. J. Immunol. (2002)
- Distinct mechanisms of internalization of Neisseria gonorrhoeae by members of the CEACAM receptor family involving Rac1- and Cdc42-dependent and -independent pathways. Billker, O., Popp, A., Brinkmann, V., Wenig, G., Schneider, J., Caron, E., Meyer, T.F. EMBO J. (2002)
- Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain isoform by glycosylphosphatidylinositol-linked proteins in human leukocytes. Singer, B.B., Scheffrahn, I., Heymann, R., Sigmundsson, K., Kammerer, R., Obrink, B. J. Immunol. (2002)
- The critical role of residues 43R and 44Q of carcinoembryonic antigen cell adhesion molecules-1 in the protection from killing by human NK cells. Markel, G., Gruda, R., Achdout, H., Katz, G., Nechama, M., Blumberg, R.S., Kammerer, R., Zimmermann, W., Mandelboim, O. J. Immunol. (2004)
- Carcinoembryonic antigen family receptor specificity of Neisseria meningitidis Opa variants influences adherence to and invasion of proinflammatory cytokine-activated endothelial cells. Muenzner, P., Dehio, C., Fujiwara, T., Achtman, M., Meyer, T.F., Gray-Owen, S.D. Infect. Immun. (2000)
- Engulfment of Neisseria gonorrhoeae: revealing distinct processes of bacterial entry by individual carcinoembryonic antigen-related cellular adhesion molecule family receptors. McCaw, S.E., Liao, E.H., Gray-Owen, S.D. Infect. Immun. (2004)
- Molecular cloning of a cDNA coding biliary glycoprotein I: primary structure of a glycoprotein immunologically crossreactive with carcinoembryonic antigen. Hinoda, Y., Neumaier, M., Hefta, S.A., Drzeniek, Z., Wagener, C., Shively, L., Hefta, L.J., Shively, J.E., Paxton, R.J. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Differential regulation of carcinoembryonic antigen and biliary glycoprotein by gamma-interferon. Takahashi, H., Okai, Y., Paxton, R.J., Hefta, L.J., Shively, J.E. Cancer Res. (1993)
- CD66: role in the regulation of neutrophil effector function. Stocks, S.C., Ruchaud-Sparagano, M.H., Kerr, M.A., Grunert, F., Haslett, C., Dransfield, I. Eur. J. Immunol. (1996)
- CEACAM1 dynamics during neisseria gonorrhoeae suppression of CD4+ T lymphocyte activation. Lee, H.S., Ostrowski, M.A., Gray-Owen, S.D. J. Immunol. (2008)
- CEACAM1, an adhesion molecule of human granulocytes, is fucosylated by fucosyltransferase IX and interacts with DC-SIGN of dendritic cells via Lewis x residues. Bogoevska, V., Horst, A., Klampe, B., Lucka, L., Wagener, C., Nollau, P. Glycobiology (2006)
- CEACAM1 functionally interacts with filamin A and exerts a dual role in the regulation of cell migration. Klaile, E., Müller, M.M., Kannicht, C., Singer, B.B., Lucka, L. J. Cell. Sci. (2005)
- CEACAM1, a cell-cell adhesion molecule, directly associates with annexin II in a three-dimensional model of mammary morphogenesis. Kirshner, J., Schumann, D., Shively, J.E. J. Biol. Chem. (2003)
- Corticotropin-releasing hormone modulates human trophoblast invasion through carcinoembryonic antigen-related cell adhesion molecule-1 regulation. Bamberger, A.M., Minas, V., Kalantaridou, S.N., Radde, J., Sadeghian, H., Löning, T., Charalampopoulos, I., Brümmer, J., Wagener, C., Bamberger, C.M., Schulte, H.M., Chrousos, G.P., Makrigiannakis, A. Am. J. Pathol. (2006)
- Dual role of carcinoembryonic antigen-related cell adhesion molecule 1 in angiogenesis and invasion of human urinary bladder cancer. Oliveira-Ferrer, L., Tilki, D., Ziegeler, G., Hauschild, J., Loges, S., Irmak, S., Kilic, E., Huland, H., Friedrich, M., Ergün, S. Cancer Res. (2004)
- CEA-related cell adhesion molecule-1 is involved in angiogenic switch in prostate cancer. Tilki, D., Irmak, S., Oliveira-Ferrer, L., Hauschild, J., Miethe, K., Atakaya, H., Hammerer, P., Friedrich, M.G., Schuch, G., Galalae, R., Stief, C.G., Kilic, E., Huland, H., Ergun, S. Oncogene (2006)
- CEACAM1 (CD66a) Promotes Human Monocyte Survival via a Phosphatidylinositol 3-Kinase- and AKT-dependent Pathway. Yu, Q., Chow, E.M., Wong, H., Gu, J., Mandelboim, O., Gray-Owen, S.D., Ostrowski, M.A. J. Biol. Chem. (2006)
- Phosphatidylinositol 3-kinases in carcinoembryonic antigen-related cellular adhesion molecule-mediated internalization of Neisseria gonorrhoeae. Booth, J.W., Telio, D., Liao, E.H., McCaw, S.E., Matsuo, T., Grinstein, S., Gray-Owen, S.D. J. Biol. Chem. (2003)
- Expression of four CEA family antigens (CEA, NCA, BGP and CGM2) in normal and cancerous gastric epithelial cells: up-regulation of BGP and CGM2 in carcinomas. Kinugasa, T., Kuroki, M., Takeo, H., Matsuo, Y., Ohshima, K., Yamashita, Y., Shirakusa, T., Matsuoka, Y. Int. J. Cancer (1998)
- Biliary glycoprotein (BGPa, CD66a, CEACAM1) mediates inhibitory signals. Chen, T., Zimmermann, W., Parker, J., Chen, I., Maeda, A., Bolland, S. J. Leukoc. Biol. (2001)
- Carcinoembryonic antigen-related cell adhesion molecule 1 is the 85-kilodalton pronase-resistant biliary glycoprotein in the cholesterol crystallization promoting low density protein-lipid complex. Jirsa, M., Muchová, L., Dráberová, L., Dráber, P., Smíd, F., Kuroki, M., Marecek, Z., Groen, A.K. Hepatology (2001)
- Soluble isoforms of CEACAM1 containing the A2 domain: increased serum levels in patients with obstructive jaundice and differences in 3-fucosyl-N-acetyl-lactosamine moiety. Dráberová, L., Cerná, H., Brodská, H., Boubelík, M., Watt, S.M., Stanners, C.P., Dráber, P. Immunology (2000)
- CD66 carcinoembryonic antigens mediate interactions between Opa-expressing Neisseria gonorrhoeae and human polymorphonuclear phagocytes. Gray-Owen, S.D., Dehio, C., Haude, A., Grunert, F., Meyer, T.F. EMBO J. (1997)
- Immunofluorescence studies on the occurrence and localization of the CEA-related biliary glycoprotein I (BGP I) in normal human gastrointestinal tissues. Svenberg, T., Hammarström, S., Zeromski, J. Clin. Exp. Immunol. (1979)