Gene Review:
SLC5A3 - solute carrier family 5 (sodium/myo...
Homo sapiens
Synonyms:
BCW2, Na(+)/myo-inositol cotransporter, SMIT, SMIT1, SMIT2, ...
- The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3): molecular cloning and localization to chromosome 21. Berry, G.T., Mallee, J.J., Kwon, H.M., Rim, J.S., Mulla, W.R., Muenke, M., Spinner, N.B. Genomics (1995)
- The 21q22.1 STS marker, VN02 (EST00541 cDNA), is part of the 3' sequence of the human Na+/myo-inositol cotransporter (SLC5A3) gene. Berry, G.T., Mallee, J.J., Blouin, J.L., Antonarakis, S.E. Cytogenet. Cell Genet. (1996)
- Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity. Miyakawa, H., Woo, S.K., Dahl, S.C., Handler, J.S., Kwon, H.M. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Triglyceride-rich lipoproteins of subjects heterozygous for apolipoprotein E2(Lys146-->Gln) are inefficiently converted to cholesterol-rich lipoproteins. Mulder, M., van der Boom, H., de Knijff, P., Braam, C., van den Maagdenberg, A., Leuven, J.A., Havekes, L.M. Atherosclerosis (1994)
- The phylogenetic relationships of Caulobacter, Asticcacaulis and Brevundimonas species and their taxonomic implications. Sly, L.I., Cox, T.L., Beckenham, T.B. Int. J. Syst. Bacteriol. (1999)
- Expression of the sodium-myo-inositol cotransporter SMIT2 at the apical membrane of Madin-Darby canine kidney cells. Bissonnette, P., Coady, M.J., Lapointe, J.Y. J. Physiol. (Lond.) (2004)
- The structural organization of the human Na+/myo-inositol cotransporter (SLC5A3) gene and characterization of the promoter. Mallee, J.J., Atta, M.G., Lorica, V., Rim, J.S., Kwon, H.M., Lucente, A.D., Wang, Y., Berry, G.T. Genomics (1997)
- In vivo brain myo-inositol levels in children with Down syndrome. Berry, G.T., Wang, Z.J., Dreha, S.F., Finucane, B.M., Zimmerman, R.A. J. Pediatr. (1999)
- Amino acid depletion activates TonEBP and sodium-coupled inositol transport. Franchi-Gazzola, R., Visigalli, R., Dall'Asta, V., Sala, R., Woo, S.K., Kwon, H.M., Gazzola, G.C., Bussolati, O. Am. J. Physiol., Cell Physiol. (2001)
- Sodium-myo-inositol co-transporter (SMIT-1) mRNA is increased in neutrophils of patients with bipolar 1 disorder and down-regulated under treatment with mood stabilizers. Willmroth, F., Drieling, T., Lamla, U., Marcushen, M., Wark, H.J., van Calker, D. Int. J. Neuropsychopharmacol. (2007)
- Osmolyte strategy in human monocytes and macrophages: involvement of p38MAPK in hyperosmotic induction of betaine and myoinositol transporters. Denkert, C., Warskulat, U., Hensel, F., Häussinger, D. Arch. Biochem. Biophys. (1998)
- Diffuse brain injury induces local expression of Na+/myo-inositol cotransporter in the rat brain. Ueda, T., Iwata, A., Komatsu, H., Aihara, N., Yamada, K., Ugawa, S., Shimada, S. Brain Res. Mol. Brain Res. (2001)
- Imbalance of glial-neuronal interaction in synapses: a possible mechanism of the pathophysiology of bipolar disorder. Mitterauer, B. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. (2004)
- Alternate splicing in human Na+-MI cotransporter gene yields differentially regulated transport isoforms. Porcellati, F., Hosaka, Y., Hlaing, T., Togawa, M., Larkin, D.D., Karihaloo, A., Stevens, M.J., Killen, P.D., Greene, D.A. Am. J. Physiol. (1999)
- Effect of TNF-alpha on SMIT mRNA levels and myo-inositol accumulation in cultured endothelial cells. Yorek, M.A., Dunlap, J.A., Thomas, M.J., Cammarata, P.R., Zhou, C., Lowe, W.L. Am. J. Physiol. (1998)
- Response of human cells to desiccation: comparison with hyperosmotic stress response. Huang, Z., Tunnacliffe, A. J. Physiol. (Lond.) (2004)
- Inhibition of inositol uptake in astrocytes by antisense oligonucleotides delivered by pH-sensitive liposomes. Lubrich, B., van Calker, D., Peschka-Süss, R. Eur. J. Biochem. (2000)