Gene Review:
SLC6A1 - solute carrier family 6 (neurotransmitter...
Homo sapiens
Synonyms:
GABATHG, GABATR, GABT1, GAT-1, GAT1, ...
- Expression of the gamma-aminobutyric acid (GABA) plasma membrane transporter-1 in monkey and human retina. Casini, G., Rickman, D.W., Brecha, N.C. Invest. Ophthalmol. Vis. Sci. (2006)
- GAT1 and GAT3 expression are differently localized in the human epileptogenic hippocampus. Lee, T.S., Bjørnsen, L.P., Paz, C., Kim, J.H., Spencer, S.S., Spencer, D.D., Eid, T., de Lanerolle, N.C. Acta Neuropathol. (2006)
- GABA transporters (GAT-1) in Alzheimer's disease. Nägga, K., Bogdanovic, N., Marcusson, J. Journal of neural transmission (Vienna, Austria : 1996) (1999)
- Sodium cotransport proteins. Wright, E.M., Hager, K.M., Turk, E. Curr. Opin. Cell Biol. (1992)
- Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A. Deken, S.L., Beckman, M.L., Boos, L., Quick, M.W. Nat. Neurosci. (2000)
- Substrates regulate gamma-aminobutyric acid transporters in a syntaxin 1A-dependent manner. Quick, M.W. Proc. Natl. Acad. Sci. U.S.A. (2002)
- A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia. Woo, T.U., Whitehead, R.E., Melchitzky, D.S., Lewis, D.A. Proc. Natl. Acad. Sci. U.S.A. (1998)
- L-proline and L-pipecolate induce enkephalin-sensitive currents in human embryonic kidney 293 cells transfected with the high-affinity mammalian brain L-proline transporter. Galli, A., Jayanthi, L.D., Ramsey, I.S., Miller, J.W., Fremeau, R.T., DeFelice, L.J. J. Neurosci. (1999)
- Substrate-induced regulation of gamma-aminobutyric acid transporter trafficking requires tyrosine phosphorylation. Whitworth, T.L., Quick, M.W. J. Biol. Chem. (2001)
- Proximity of transmembrane domains 1 and 3 of the gamma-aminobutyric acid transporter GAT-1 inferred from paired cysteine mutagenesis. Zomot, E., Zhou, Y., Kanner, B.I. J. Biol. Chem. (2005)
- SNAP-25/Syntaxin 1A Complex Functionally Modulates Neurotransmitter {gamma}-Aminobutyric Acid Reuptake. Fan, H.P., Fan, F.J., Bao, L., Pei, G. J. Biol. Chem. (2006)
- Inhibitory networks in epilepsy-associated gangliogliomas and in the perilesional epileptic cortex. Aronica, E., Redeker, S., Boer, K., Spliet, W.G., van Rijen, P.C., Gorter, J.A., Troost, D. Epilepsy Res. (2007)
- Protein kinase C regulates the interaction between a GABA transporter and syntaxin 1A. Beckman, M.L., Bernstein, E.M., Quick, M.W. J. Neurosci. (1998)
- Neuronal and glial localization of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in human cerebral cortex: with a note on its distribution in monkey cortex. Conti, F., Melone, M., De Biasi, S., Minelli, A., Brecha, N.C., Ducati, A. J. Comp. Neurol. (1998)
- The membrane topology of GAT-1, a (Na+ + Cl-)-coupled gamma-aminobutyric acid transporter from rat brain. Bennett, E.R., Kanner, B.I. J. Biol. Chem. (1997)
- Transmembrane domain I of the gamma-aminobutyric acid transporter GAT-1 plays a crucial role in the transition between cation leak and transport modes. Kanner, B.I. J. Biol. Chem. (2003)
- The interaction of the gamma-aminobutyric acid transporter GAT-1 with the neurotransmitter is selectively impaired by sulfhydryl modification of a conformationally sensitive cysteine residue engineered into extracellular loop IV. Zomot, E., Kanner, B.I. J. Biol. Chem. (2003)
- Tyrosine 140 of the gamma-aminobutyric acid transporter GAT-1 plays a critical role in neurotransmitter recognition. Bismuth, Y., Kavanaugh, M.P., Kanner, B.I. J. Biol. Chem. (1997)
- The Transmembrane Sodium Gradient Influences Ambient GABA Concentration by Altering the Equilibrium of GABA Transporters. Wu, Y., Wang, W., Richerson, G.B. J. Neurophysiol. (2006)
- Action of bicyclic isoxazole GABA analogues on GABA transporters and its relation to anticonvulsant activity. Bolvig, T., Larsson, O.M., Pickering, D.S., Nelson, N., Falch, E., Krogsgaard-Larsen, P., Schousboe, A. Eur. J. Pharmacol. (1999)
- Localization of calcium-binding proteins and GABA transporter (GAT-1) messenger RNA in the human subthalamic nucleus. Augood, S.J., Waldvogel, H.J., Münkle, M.C., Faull, R.L., Emson, P.C. Neuroscience (1999)
- Deletion of the GABA(A) receptor alpha1 subunit increases tonic GABA(A) receptor current: a role for GABA uptake transporters. Ortinski, P.I., Turner, J.R., Barberis, A., Motamedi, G., Yasuda, R.P., Wolfe, B.B., Kellar, K.J., Vicini, S. J. Neurosci. (2006)
- GAD67 and GAD65 mRNA and protein expression in cerebrocortical regions of elderly patients with schizophrenia. Dracheva, S., Elhakem, S.L., McGurk, S.R., Davis, K.L., Haroutunian, V. J. Neurosci. Res. (2004)
- Expression of GABA transporters on bullfrog retinal Müller cells. Zhao, J.W., Du, J.L., Li, J.S., Yang, X.L. Glia (2000)
- A light and electron microscopic study of GAT-1-positive cells in the cerebral cortex of man and monkey. Ong, W.Y., Yeo, T.T., Balcar, V.J., Garey, L.J. J. Neurocytol. (1998)
- Rapid substrate-induced charge movements of the GABA transporter GAT1. Bicho, A., Grewer, C. Biophys. J. (2005)
- Molecular cloning and structure of the human (GABATHG) GABA transporter gene. Lam, D.M., Fei, J., Zhang, X.Y., Tam, A.C., Zhu, L.H., Huang, F., King, S.C., Guo, L.H. Brain Res. Mol. Brain Res. (1993)