Gene Review:
SLC10A1 - solute carrier family 10 (sodium/bile acid...
Homo sapiens
Synonyms:
Cell growth-inhibiting gene 29 protein, GIG29, NTCP, Na(+)/bile acid cotransporter, Na(+)/taurocholate transport protein, ...
- Protein kinase C-dependent distribution of the multidrug resistance protein 2 from the canalicular to the basolateral membrane in human HepG2 cells. Kubitz, R., Huth, C., Schmitt, M., Horbach, A., Kullak-Ublick, G., Häussinger, D. Hepatology (2001)
- Developmental expression of canalicular transporter genes in human liver. Chen, H.L., Chen, H.L., Liu, Y.J., Feng, C.H., Wu, C.Y., Shyu, M.K., Yuan, R.H., Chang, M.H. J. Hepatol. (2005)
- Chlorambucil-taurocholate is transported by bile acid carriers expressed in human hepatocellular carcinomas. Kullak-Ublick, G.A., Glasa, J., Böker, C., Oswald, M., Grützner, U., Hagenbuch, B., Stieger, B., Meier, P.J., Beuers, U., Kramer, W., Wess, G., Paumgartner, G. Gastroenterology (1997)
- Hepatic basolateral sodium-dependent-bile acid transporter expression in two unusual cases of hypercholanemia and in extrahepatic biliary atresia. Shneider, B.L., Fox, V.L., Schwarz, K.B., Watson, C.L., Ananthanarayanan, M., Thevananther, S., Christie, D.M., Hardikar, W., Setchell, K.D., Mieli-Vergani, G., Suchy, F.J., Mowat, A.P. Hepatology (1997)
- Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter. Hagenbuch, B., Meier, P.J. J. Clin. Invest. (1994)
- Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. Ho, R.H., Tirona, R.G., Leake, B.F., Glaeser, H., Lee, W., Lemke, C.J., Wang, Y., Kim, R.B. Gastroenterology (2006)
- Molecular regulation of sinusoidal liver bile acid transporters during cholestasis. Gartung, C., Matern, S. The Yale journal of biology and medicine. (1997)
- The human Na+-taurocholate cotransporting polypeptide gene is activated by glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma coactivator-1alpha, and suppressed by bile acids via a small heterodimer partner-dependent mechanism. Eloranta, J.J., Jung, D., Kullak-Ublick, G.A. Mol. Endocrinol. (2006)
- Structural and functional characterization of liver cell-specific activity of the human sodium/taurocholate cotransporter. Shiao, T., Iwahashi, M., Fortune, J., Quattrochi, L., Bowman, S., Wick, M., Qadri, I., Simon, F.R. Genomics (2000)
- Inhibition of bile acid transport across Na+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs. Mita, S., Suzuki, H., Akita, H., Hayashi, H., Onuki, R., Hofmann, A.F., Sugiyama, Y. Drug Metab. Dispos. (2006)
- Dephosphorylation of Ser-226 facilitates plasma membrane retention of Ntcp. Anwer, M.S., Gillin, H., Mukhopadhyay, S., Balasubramaniyan, N., Suchy, F.J., Ananthanarayanan, M. J. Biol. Chem. (2005)
- Novel bile acid derivatives (BANBs) with cytostatic activity obtained by conjugation of their side chain with nitrogenated bases. Vallejo, M., Castro, M.A., Medarde, M., Macias, R.I., Romero, M.R., El-Mir, M.Y., Monte, M.J., Briz, O., Serrano, M.A., Marin, J.J. Biochem. Pharmacol. (2007)
- The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp. Denson, L.A., Sturm, E., Echevarria, W., Zimmerman, T.L., Makishima, M., Mangelsdorf, D.J., Karpen, S.J. Gastroenterology (2001)
- Cloning and expression of SLC10A4, a putative organic anion transport protein. Splinter, P.L., Lazaridis, K.N., Dawson, P.A., Larusso, N.F. World J. Gastroenterol. (2006)
- Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes. McRae, M.P., Lowe, C.M., Tian, X., Bourdet, D.L., Ho, R.H., Leake, B.F., Kim, R.B., Brouwer, K.L., Kashuba, A.D. J. Pharmacol. Exp. Ther. (2006)
- Enterohepatic bile salt transporters in normal physiology and liver disease. Kullak-Ublick, G.A., Stieger, B., Meier, P.J. Gastroenterology (2004)
- Hepatobiliary transporter expression in human hepatocellular carcinoma. Zollner, G., Wagner, M., Fickert, P., Silbert, D., Fuchsbichler, A., Zatloukal, K., Denk, H., Trauner, M. Liver Int. (2005)
- Disrupted coordinate regulation of farnesoid X receptor target genes in a patient with cerebrotendinous xanthomatosis. Honda, A., Salen, G., Matsuzaki, Y., Batta, A.K., Xu, G., Hirayama, T., Tint, G.S., Doy, M., Shefer, S. J. Lipid Res. (2005)
- Role of liver-enriched transcription factors and nuclear receptors in regulating the human, mouse, and rat NTCP gene. Jung, D., Hagenbuch, B., Fried, M., Meier, P.J., Kullak-Ublick, G.A. Am. J. Physiol. Gastrointest. Liver Physiol. (2004)
- Molecular and functional characterization of bile acid transport in human hepatoblastoma HepG2 cells. Kullak-Ublick, G.A., Beuers, U., Paumgartner, G. Hepatology (1996)