Gene Review:
SMARCA2 - SWI/SNF related, matrix associated, actin...
Homo sapiens
Synonyms:
ATP-dependent helicase SMARCA2, BAF190, BAF190B, BRG1-associated factor 190B, BRM, ...
- Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers. Perani, M., Ingram, C.J., Cooper, C.S., Garrett, M.D., Goodwin, G.H. Oncogene (2003)
- Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis. Reisman, D.N., Sciarrotta, J., Wang, W., Funkhouser, W.K., Weissman, B.E. Cancer Res. (2003)
- Retinoblastoma protein is functionally distinct from its homologues in affecting glucocorticoid receptor-mediated transcription and apoptosis. Singh, P., Chan, S.W., Hong, W. J. Biol. Chem. (2001)
- BRG1 loss in MiaPaCa2 cells induces an altered cellular morphology and disruption in the organization of the actin cytoskeleton. Rosson, G.B., Bartlett, C., Reed, W., Weissman, B.E. J. Cell. Physiol. (2005)
- Aminopeptidase inhibitor ubenimex (bestatin) inhibits the growth of human choriocarcinoma in nude mice through its direct cytostatic activity. Inoi, K., Goto, S., Nomura, S., Isobe, K., Nawa, A., Okamoto, T., Tomoda, Y. Anticancer Res. (1995)
- Identification of a polymorphic, neuron-specific chromatin remodeling complex. Olave, I., Wang, W., Xue, Y., Kuo, A., Crabtree, G.R. Genes Dev. (2002)
- Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes. Kadam, S., Emerson, B.M. Mol. Cell (2003)
- BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonists. Wang, S., Zhang, B., Faller, D.V. EMBO J. (2004)
- Functional Differentiation of SWI/SNF Remodelers in Transcription and Cell Cycle Control. Moshkin, Y.M., Mohrmann, L., van Ijcken, W.F., Verrijzer, C.P. Mol. Cell. Biol. (2007)
- Brain-specific expression of the nuclear actin-related protein ArpNalpha and its involvement in mammalian SWI/SNF chromatin remodeling complex. Kuroda, Y., Oma, Y., Nishimori, K., Ohta, T., Harata, M. Biochem. Biophys. Res. Commun. (2002)
- Expression of chromatin remodeling factors during neural differentiation. Machida, Y., Murai, K., Miyake, K., Iijima, S. J. Biochem. (2001)
- SMARCA2 and THAP11: potential candidates for polyglutamine disorders as evidenced from polymorphism and protein-folding simulation studies. Pandey, N., Mittal, U., Srivastava, A.K., Mukerji, M. J. Hum. Genet. (2004)
- Association study of the trinucleotide repeat polymorphism within SMARCA2 and schizophrenia. Sengupta, S., Xiong, L., Fathalli, F., Benkelfat, C., Tabbane, K., Danics, Z., Labelle, A., Lal, S., Krebs, M.O., Rouleau, G., Joober, R. BMC Genet. (2006)
- Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies. Decristofaro, M.F., Betz, B.L., Rorie, C.J., Reisman, D.N., Wang, W., Weissman, B.E. J. Cell. Physiol. (2001)
- Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB. Betz, B.L., Strobeck, M.W., Reisman, D.N., Knudsen, E.S., Weissman, B.E. Oncogene (2002)
- Mammalian Chromatin Remodeling Complex SWI/SNF Is Essential for Enhanced Expression of the Albumin Gene during Liver Development. Inayoshi, Y., Miyake, K., Machida, Y., Kaneoka, H., Terajima, M., Dohda, T., Takahashi, M., Iijima, S. J. Biochem. (2006)
- The expression of the SWI/SNF ATPase subunits BRG1 and BRM in normal human tissues. Reisman, D.N., Sciarrotta, J., Bouldin, T.W., Weissman, B.E., Funkhouser, W.K. Appl. Immunohistochem. Mol. Morphol. (2005)
- Cyclosporine bone remodeling effect prevents steroid osteopenia after kidney transplantation. Westeel, F.P., Mazouz, H., Ezaitouni, F., Hottelart, C., Ivan, C., Fardellone, P., Brazier, M., El Esper, I., Petit, J., Achard, J.M., Pruna, A., Fournier, A. Kidney Int. (2000)
- Improvement of red mud polymer-matrix nanocomposites by red mud surface treatment. Park, S.J., Jun, B.R. Journal of colloid and interface science. (2005)
- Molecular mechanisms underlying human synovial sarcoma development. dos Santos, N.R., de Bruijn, D.R., van Kessel, A.G. Genes Chromosomes Cancer (2001)
- Transcriptional co-activator activity of SYT is negatively regulated by BRM and Brg1. Ishida, M., Tanaka, S., Ohki, M., Ohta, T. Genes Cells (2004)
- Differential requirement of SWI/SNF for androgen receptor activity. Marshall, T.W., Link, K.A., Petre-Draviam, C.E., Knudsen, K.E. J. Biol. Chem. (2003)
- Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: differential effects on RB-mediated growth arrest vs CD44 expression. Reisman, D.N., Strobeck, M.W., Betz, B.L., Sciariotta, J., Funkhouser, W., Murchardt, C., Yaniv, M., Sherman, L.S., Knudsen, E.S., Weissman, B.E. Oncogene (2002)
- Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors. Inoue, H., Furukawa, T., Giannakopoulos, S., Zhou, S., King, D.S., Tanese, N. J. Biol. Chem. (2002)
- Fusions of the SYT and SSX genes in synovial sarcoma. Ladanyi, M. Oncogene (2001)
- The BRG1- and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the cylindromatosis tumor suppressor gene. Wang, L., Baiocchi, R.A., Pal, S., Mosialos, G., Caligiuri, M., Sif, S. Mol. Cell. Biol. (2005)
- Mechanism of action of a streptococcal preparation (OK-432) in prevention of autoimmune diabetes in NOD mice. Suppression of generation of effector cells for pancreatic B cell destruction. Shintani, S., Satoh, J., Seino, H., Goto, Y., Toyota, T. J. Immunol. (1990)
- Opioid receptor ligand binding in the human striatum: II. Heterogeneous distribution of kappa opioid receptor labeled with [3H]bremazocine. Vonkeman, H.E., Voorn, P., Brady, L.S., Berendse, H.W., Richfield, E.K. J. Comp. Neurol. (1996)
- Effect of krestin (PSK) as adjuvant treatment on the prognosis after radical radiotherapy in patients with non-small cell lung cancer. Hayakawa, K., Mitsuhashi, N., Saito, Y., Takahashi, M., Katano, S., Shiojima, K., Furuta, M., Niibe, H. Anticancer Res. (1993)
- Clinical significance of autologous tumor killing (ATK) activity and its induction therapy in human cancer. Uchida, A. Biotherapy (Dordrecht, Netherlands) (1994)
- A wavelet coefficient smoothened RLS adaptive denoising model for ECG. Poornachandra, S., Kumaravel, N. Biomedical sciences instrumentation. (2003)