Gene Review:
SUV39H1 - suppressor of variegation 3-9 homolog 1...
Homo sapiens
Synonyms:
H3-K9-HMTase 1, Histone H3-K9 methyltransferase 1, Histone-lysine N-methyltransferase SUV39H1, KMT1A, Lysine N-methyltransferase 1A, ...
- RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription. Reed-Inderbitzin, E., Moreno-Miralles, I., Vanden-Eynden, S.K., Xie, J., Lutterbach, B., Durst-Goodwin, K.L., Luce, K.S., Irvin, B.J., Cleary, M.L., Brandt, S.J., Hiebert, S.W. Oncogene (2006)
- Rb targets histone H3 methylation and HP1 to promoters. Nielsen, S.J., Schneider, R., Bauer, U.M., Bannister, A.J., Morrison, A., O'Carroll, D., Firestein, R., Cleary, M., Jenuwein, T., Herrera, R.E., Kouzarides, T. Nature (2001)
- Regulation of chromatin structure by site-specific histone H3 methyltransferases. Rea, S., Eisenhaber, F., O'Carroll, D., Strahl, B.D., Sun, Z.W., Schmid, M., Opravil, S., Mechtler, K., Ponting, C.P., Allis, C.D., Jenuwein, T. Nature (2000)
- Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication. Est??ve, P.O., Chin, H.G., Smallwood, A., Feehery, G.R., Gangisetty, O., Karpf, A.R., Carey, M.F., Pradhan, S. Genes Dev. (2006)
- Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase. Wang, H., Cao, R., Xia, L., Erdjument-Bromage, H., Borchers, C., Tempst, P., Zhang, Y. Mol. Cell (2001)
- Self-interaction of heterochromatin protein 1 is required for direct binding to histone methyltransferase, SUV39H1. Yamamoto, K., Sonoda, M. Biochem. Biophys. Res. Commun. (2003)
- Set domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9. Firestein, R., Cui, X., Huie, P., Cleary, M.L. Mol. Cell. Biol. (2000)
- Mitotic phosphorylation of SUV39H1, a novel component of active centromeres, coincides with transient accumulation at mammalian centromeres. Aagaard, L., Schmid, M., Warburton, P., Jenuwein, T. J. Cell. Sci. (2000)
- Over-expression of the SUV39H1 histone methyltransferase induces altered proliferation and differentiation in transgenic mice. Czvitkovich, S., Sauer, S., Peters, A.H., Deiner, E., Wolf, A., Laible, G., Opravil, S., Beug, H., Jenuwein, T. Mech. Dev. (2001)
- Recruitment of the histone methyltransferase SUV39H1 and its role in the oncogenic properties of the leukemia-associated PML-retinoic acid receptor fusion protein. Carbone, R., Botrugno, O.A., Ronzoni, S., Insinga, A., Di Croce, L., Pelicci, P.G., Minucci, S. Mol. Cell. Biol. (2006)
- Accumulation of heterochromatin components on the terminal repeat sequence of Kaposi's sarcoma-associated herpesvirus mediated by the latency-associated nuclear antigen. Sakakibara, S., Ueda, K., Nishimura, K., Do, E., Ohsaki, E., Okuno, T., Yamanishi, K. J. Virol. (2004)
- Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis. Chin, H.G., Patnaik, D., Estève, P.O., Jacobsen, S.E., Pradhan, S. Biochemistry (2006)
- The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Fuks, F., Hurd, P.J., Deplus, R., Kouzarides, T. Nucleic Acids Res. (2003)
- Activation of the beta globin locus by transcription factors and chromatin modifiers. McMorrow, T., van den Wijngaard, A., Wollenschlaeger, A., van de Corput, M., Monkhorst, K., Trimborn, T., Fraser, P., van Lohuizen, M., Jenuwein, T., Djabali, M., Philipsen, S., Grosveld, F., Milot, E. EMBO J. (2000)
- Disruption of the gene Euchromatin Histone Methyl Transferase1 (Eu-HMTase1) is associated with the 9q34 subtelomeric deletion syndrome. Kleefstra, T., Smidt, M., Banning, M.J., Oudakker, A.R., Van Esch, H., de Brouwer, A.P., Nillesen, W., Sistermans, E.A., Hamel, B.C., de Bruijn, D., Fryns, J.P., Yntema, H.G., Brunner, H.G., de Vries, B.B., van Bokhoven, H. J. Med. Genet. (2005)