Gene Review:
TAL1 - T-cell acute lymphocytic leukemia 1
Homo sapiens
Synonyms:
BHLHA17, Class A basic helix-loop-helix protein 17, SCL, Stem cell protein, T-cell acute lymphocytic leukemia protein 1, ...
- P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL. Huang, S., Qiu, Y., Shi, Y., Xu, Z., Brandt, S.J. EMBO J. (2000)
- Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice. Larson, R.C., Lavenir, I., Larson, T.A., Baer, R., Warren, A.J., Wadman, I., Nottage, K., Rabbitts, T.H. EMBO J. (1996)
- Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells. Hsu, H.L., Wadman, I., Baer, R. Proc. Natl. Acad. Sci. U.S.A. (1994)
- mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor. Huang, S., Brandt, S.J. Mol. Cell. Biol. (2000)
- SCL/TAL1 expression level regulates human hematopoietic stem cell self-renewal and engraftment. Reynaud, D., Ravet, E., Titeux, M., Mazurier, F., Rénia, L., Dubart-Kupperschmitt, A., Roméo, P.H., Pflumio, F. Blood (2005)
- Coordinate expression and developmental role of Id2 protein and TAL1/E2A heterodimer in erythroid progenitor differentiation. Condorelli, G., Vitelli, L., Valtieri, M., Marta, I., Montesoro, E., Lulli, V., Baer, R., Peschle, C. Blood (1995)
- Stem cell strategies for Alzheimer's disease therapy. Sugaya, K., Alvarez, A., Marutle, A., Kwak, Y.D., Choumkina, E. Panminerva medica. (2006)
- The value of the Claybury Selection Battery in predicting benefit from group psychotherapy. Pearson, M.J., Girling, A.J. The British journal of psychiatry : the journal of mental science. (1990)
- Stem cell transplantation for Huntington's disease. Dunnett, S.B., Rosser, A.E. Exp. Neurol. (2007)
- Psychological characteristics of a sample of male street prostitutes. Simon, P.M., Morse, E.V., Osofsky, H.J., Balson, P.M., Gaumer, H.R. Archives of sexual behavior. (1992)
- Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes. Korsmeyer, S.J. Annu. Rev. Immunol. (1992)
- Stem-cell transplantation for myelofibrosis. Deeg, H.J., Appelbaum, F.R. N. Engl. J. Med. (2001)
- Stem cell patterning and fate in human epidermis. Jones, P.H., Harper, S., Watt, F.M. Cell (1995)
- Stem-cell giveaway proposed as confusion reigns over cell count. Knight, J. Nature (2001)
- Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL. Shivdasani, R.A., Mayer, E.L., Orkin, S.H. Nature (1995)
- TAL-1 protein expression in vascular lesions. Chetty, R., Dada, M.A., Boshoff, C.H., Comley, M.A., Biddolph, S.C., Schneider, J.W., Mason, D.Y., Pulford, K.A., Gatter, K.C. J. Pathol. (1997)
- Stem cell transplantation for patients with Fanconi anemia with low-dose cyclophosphamide and antithymocyte globulins without the use of radiation therapy. Ayas, M., Al-Jefri, A., Al-Mahr, M., Rifai, S., Al-Seraihi, A., Tbakhi, A., Mustafa, M., Khairy, A., Moussa, E., Iqbal, A., Shalaby, L., El-Solh, H. Bone Marrow Transplant. (2005)
- Stem cell genes in androgen-independent prostate cancer. Bui, M., Reiter, R.E. Cancer Metastasis Rev. (1998)
- Case report: Invasive aspergillosis successfully treated with voriconazole without recurrence during subsequent bone marrow transplantation. Chow, E., Moore, T., Nielsen, K. Pediatr. Infect. Dis. J. (2003)
- Stem cell mobilization in resistant or relapsed lymphoma: superior yield of progenitor cells following a salvage regimen comprising ifosphamide, etoposide and epirubicin compared to intermediate-dose cyclophosphamide. McQuaker, I.G., Haynes, A.P., Stainer, C., Anderson, S., Russell, N.H. Br. J. Haematol. (1997)
- The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells. Valge-Archer, V.E., Osada, H., Warren, A.J., Forster, A., Li, J., Baer, R., Rabbitts, T.H. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL. Ono, Y., Fukuhara, N., Yoshie, O. J. Biol. Chem. (1997)
- Expression of the TAL1 proto-oncogene in cultured endothelial cells and blood vessels of the spleen. Hwang, L.Y., Siegelman, M., Davis, L., Oppenheimer-Marks, N., Baer, R. Oncogene (1993)
- Phosphorylation of the TAL1 oncoprotein by the extracellular-signal-regulated protein kinase ERK1. Cheng, J.T., Cobb, M.H., Baer, R. Mol. Cell. Biol. (1993)
- Products of the TAL1 oncogene: basic helix-loop-helix proteins phosphorylated at serine residues. Cheng, J.T., Hsu, H.L., Hwang, L.Y., Baer, R. Oncogene (1993)
- Analysis of the relationship between Scl transcription factor complex protein expression patterns and the effects of LiCl on ATRA-induced differentiation in blast cells from patients with acute myeloid leukemia. Rice, A.M., Holtz, K.M., Karp, J., Rollins, S., Sartorelli, A.C. Leuk. Res. (2004)
- PU.1/Spi-1 binds to the human TAL-1 silencer to mediate its activity. Le Clech, M., Chalhoub, E., Dohet, C., Roure, V., Fichelson, S., Moreau-Gachelin, F., Mathieu, D. J. Mol. Biol. (2006)
- Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro. Batova, A., Diccianni, M.B., Omura-Minamisawa, M., Yu, J., Carrera, C.J., Bridgeman, L.J., Kung, F.H., Pullen, J., Amylon, M.D., Yu, A.L. Cancer Res. (1999)
- Tal1/SCL binding to pericentromeric DNA represses transcription. Wen, J., Huang, S., Pack, S.D., Yu, X., Brandt, S.J., Noguchi, C.T. J. Biol. Chem. (2005)
- Chromosomal translocations and leukaemia: a role for LMO2 in T cell acute leukaemia, in transcription and in erythropoiesis. Rabbitts, T.H., Axelson, H., Forster, A., Grutz, G., Lavenir, I., Larson, R., Osada, H., Valge-Archer, V., Wadman, I., Warren, A. Leukemia (1997)
- VEGF directs newly gastrulated mesoderm to the endothelial lineage. Giles, P.B., Candy, C.L., Fleming, P.A., Owens, R.W., Argraves, W.S., Drake, C.J. Dev. Biol. (2005)
- Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy. Asnafi, V., Beldjord, K., Libura, M., Villarese, P., Millien, C., Ballerini, P., Kuhlein, E., Lafage-Pochitaloff, M., Delabesse, E., Bernard, O., Macintyre, E. Blood (2004)
- Products of the TAL2 oncogene in leukemic T cells: bHLH phosphoproteins with DNA-binding activity. Xia, Y., Hwang, L.Y., Cobb, M.H., Baer, R. Oncogene (1994)
- The LIM-only protein LMO4 modulates the transcriptional activity of HEN1. Manetopoulos, C., Hansson, A., Karlsson, J., Jönsson, J.I., Axelson, H. Biochem. Biophys. Res. Commun. (2003)
- Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia. Palomero, T., Odom, D.T., O'Neil, J., Ferrando, A.A., Margolin, A., Neuberg, D.S., Winter, S.S., Larson, R.S., Li, W., Liu, X.S., Young, R.A., Look, A.T. Blood (2006)