Gene Review:
LRP8 - low density lipoprotein receptor-related...
Homo sapiens
Synonyms:
APOER2, Apolipoprotein E receptor 2, HSZ75190, LRP-8, Low-density lipoprotein receptor-related protein 8, ...
Persico,
D'Agruma,
Zelante,
Militerni,
Bravaccio,
Schneider,
Melmed,
Trillo,
Montecchi,
Elia,
Palermo,
Rabinowitz,
Pascucci,
Puglisi-Allegra,
Reichelt,
Muscarella,
Guarnieri,
Melgari,
Conciatori,
Keller,
Motoi,
Itaya,
Mori,
Mizuno,
Iwasaki,
Hattori,
Haga,
Ikeda,
Garnis,
Campbell,
Davies,
Macaulay,
Lam,
Lam,
- Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2'. Lutters, B.C., Derksen, R.H., Tekelenburg, W.L., Lenting, P.J., Arnout, J., de Groot, P.G. J. Biol. Chem. (2003)
- Polymorphism in Maternal LRP8 Gene Is Associated with Fetal Growth. Wang, L., Wang, X., Laird, N., Zuckerman, B., Stubblefield, P., Xu, X. Am. J. Hum. Genet. (2006)
- Quantification of apolipoprotein E receptors in human brain-derived cell lines by real-time polymerase chain reaction. Thilakawardhana, S., Everett, D.M., Murdock, P.R., Dingwall, C., Owen, J.S. Neurobiol. Aging (2005)
- Low-density lipoprotein receptor-related protein 8 (apolipoprotein E receptor 2) gene polymorphisms in Alzheimer's disease. Ma, S.L., Ng, H.K., Baum, L., Pang, J.C., Chiu, H.F., Woo, J., Tang, N.L., Lam, L.C. Neurosci. Lett. (2002)
- Apoer2: a reelin receptor to remember. D'Arcangelo, G. Neuron (2005)
- Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis. Garnis, C., Campbell, J., Davies, J.J., Macaulay, C., Lam, S., Lam, W.L. Hum. Mol. Genet. (2005)
- ApoE Receptor 2 Controls Neuronal Survival in the Adult Brain. Beffert, U., Nematollah Farsian, F., Masiulis, I., Hammer, R.E., Yoon, S.O., Giehl, K.M., Herz, J. Curr. Biol. (2006)
- DAB1 and Reelin Effects on Amyloid Precursor Protein and ApoE Receptor 2 Trafficking and Processing. Hoe, H.S., Tran, T.S., Matsuoka, Y., Howell, B.W., Rebeck, G.W. J. Biol. Chem. (2006)
- Identification and characterization of LRP8 (apoER2) in human blood platelets. Riddell, D.R., Vinogradov, D.V., Stannard, A.K., Chadwick, N., Owen, J.S. J. Lipid Res. (1999)
- Expression and alternate splicing of apolipoprotein E receptor 2 in brain. Clatworthy, A.E., Stockinger, W., Christie, R.H., Schneider, W.J., Nimpf, J., Hyman, B.T., Rebeck, G.W. Neuroscience (1999)
- Interaction of beta2-glycoprotein I with members of the low density lipoprotein receptor family. Pennings, M.T., van Lummel, M., Derksen, R.H., Urbanus, R.T., Romijn, R.A., Lenting, P.J., de Groot, P.G. J. Thromb. Haemost. (2006)
- The transmembrane domain and PXXP motifs of ApoE receptor 2 exclude it from carrying out clathrin-mediated endocytosis. Sun, X.M., Soutar, A.K. J. Biol. Chem. (2003)
- Identification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissue. Korschineck, I., Ziegler, S., Breuss, J., Lang, I., Lorenz, M., Kaun, C., Ambros, P.F., Binder, B.R. J. Biol. Chem. (2001)
- Apolipoprotein E receptor 2 is involved in neuritic plaque formation in APP sw mice. Motoi, Y., Itaya, M., Mori, H., Mizuno, Y., Iwasaki, T., Hattori, H., Haga, S., Ikeda, K. Neurosci. Lett. (2004)
- Apolipoprotein E (apoE) isoforms differentially induce nitric oxide production in endothelial cells. Sacre, S.M., Stannard, A.K., Owen, J.S. FEBS Lett. (2003)
- Expression of mRNA of lipoprotein receptor related protein 8, low density lipoprotein receptor, and very low density lipoprotein receptor in bovine ovarian cells during follicular development and corpus luteum formation and regression. Argov, N., Sklan, D. Mol. Reprod. Dev. (2004)
- The binding site in {beta}2-glycoprotein I for ApoER2' on platelets is located in domain V. van Lummel, M., Pennings, M.T., Derksen, R.H., Urbanus, R.T., Lutters, B.C., Kaldenhoven, N., de Groot, P.G. J. Biol. Chem. (2005)
- Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes. Stolt, P.C., Jeon, H., Song, H.K., Herz, J., Eck, M.J., Blacklow, S.C. Structure (Camb.) (2003)
- Platelet adhesion to dimeric beta-glycoprotein I under conditions of flow is mediated by at least two receptors: glycoprotein Ibalpha and apolipoprotein E receptor 2'. Pennings, M.T., Derksen, R.H., VAN Lummel, M., Adelmeijer, J., Vanhoorelbeke, K., Urbanus, R.T., Lisman, T., DE Groot, P.G. J. Thromb. Haemost. (2007)
- Close encounters with apolipoprotein E receptors. Yamamoto, T., Bujo, H. Curr. Opin. Lipidol. (1996)
- Enhanced APOE2 transmission rates in families with autistic probands. Persico, A.M., D'Agruma, L., Zelante, L., Militerni, R., Bravaccio, C., Schneider, C., Melmed, R., Trillo, S., Montecchi, F., Elia, M., Palermo, M., Rabinowitz, D., Pascucci, T., Puglisi-Allegra, S., Reichelt, K.L., Muscarella, L., Guarnieri, V., Melgari, J.M., Conciatori, M., Keller, F. Psychiatr. Genet. (2004)
- Expression in vitro of alternatively spliced variants of the messenger RNA for human apolipoprotein E receptor-2 identified in human tissues by ribonuclease protection assays. Sun, X.M., Soutar, A.K. Eur. J. Biochem. (1999)
- Localization of apolipoprotein E receptor 2 to caveolae in the plasma membrane. Riddell, D.R., Sun, X.M., Stannard, A.K., Soutar, A.K., Owen, J.S. J. Lipid Res. (2001)