Gene Review:
MAPKAP1 - mitogen-activated protein kinase...
Homo sapiens
Synonyms:
JC310, MGC2745, MIP1, Mitogen-activated protein kinase 2-associated protein 1, SAPK-interacting protein 1, ...
- SIN-1 reduces platelet adhesion and platelet thrombus formation in a porcine model of balloon angioplasty. Groves, P.H., Lewis, M.J., Cheadle, H.A., Penny, W.J. Circulation (1993)
- Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms. Brandi, M.L., Hukkanen, M., Umeda, T., Moradi-Bidhendi, N., Bianchi, S., Gross, S.S., Polak, J.M., MacIntyre, I. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Neuronal differentiation and protection from nitric oxide-induced apoptosis require c-Jun-dependent expression of NCAM140. Feng, Z., Li, L., Ng, P.Y., Porter, A.G. Mol. Cell. Biol. (2002)
- Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells. Cobbs, C.S., Whisenhunt, T.R., Wesemann, D.R., Harkins, L.E., Van Meir, E.G., Samanta, M. Cancer Res. (2003)
- Activation of mitogen-activated protein kinase associated with prostate cancer progression. Gioeli, D., Mandell, J.W., Petroni, G.R., Frierson, H.F., Weber, M.J. Cancer Res. (1999)
- Preliminary results with the nitric oxide donor linsidomine chlorhydrate in the treatment of human erectile dysfunction. Stief, C.G., Holmquist, F., Djamilian, M., Krah, H., Andersson, K.E., Jonas, U. J. Urol. (1992)
- SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity. Jacinto, E., Facchinetti, V., Liu, D., Soto, N., Wei, S., Jung, S.Y., Huang, Q., Qin, J., Su, B. Cell (2006)
- ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Roux, P.P., Blenis, J. Microbiol. Mol. Biol. Rev. (2004)
- Nitric oxide regulates the calcium current in isolated human atrial myocytes. Kirstein, M., Rivet-Bastide, M., Hatem, S., Bénardeau, A., Mercadier, J.J., Fischmeister, R. J. Clin. Invest. (1995)
- Increased cytotoxicity of 3-morpholinosydnonimine to HepG2 cells in the presence of superoxide dismutase. Role of hydrogen peroxide and iron. Gergel, D., Misík, V., Ondrias, K., Cederbaum, A.I. J. Biol. Chem. (1995)
- Protection against the co-operative toxicity of nitric oxide and oxygen free radicals by overexpression of antioxidant enzymes in bioengineered insulin-producing RINm5F cells. Tiedge, M., Lortz, S., Munday, R., Lenzen, S. Diabetologia (1999)
- Differential mechanisms of nitric oxide- and peroxynitrite-induced cell death. Meij, J.T., Haselton, C.L., Hillman, K.L., Muralikrishnan, D., Ebadi, M., Yu, L. Mol. Pharmacol. (2004)
- Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite. Thomas, S.R., Davies, M.J., Stocker, R. Chem. Res. Toxicol. (1998)
- The human stress-activated protein kinase-interacting 1 gene encodes JNK-binding proteins. Schroder, W., Bushell, G., Sculley, T. Cell. Signal. (2005)
- Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene. Schroder, W., Cloonan, N., Bushell, G., Sculley, T. Gene (2004)
- Differential expression levels of the heat shock protein 27 isoforms in pediatric normal, nonleukemic and common acute lymphoblastic leukemia B-cell precursors. Madsen, P.S., Hokland, P., Clausen, N., Ellegaard, J., Hokland, M. Blood (1995)
- Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha. Buck, M., Zhang, L., Halasz, N.A., Hunter, T., Chojkier, M. EMBO J. (2001)
- Sympathetic stimulation overrides flow-mediated endothelium-dependent epicardial coronary vasodilation in transplant patients. Aptecar, E., Dupouy, P., Benvenuti, C., Mazzucotelli, J.P., Teiger, E., Geschwind, H., Castaigne, A., Loisance, D., Dubois-Rande, J.L. Circulation (1996)
- Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veins. Lüscher, T.F., Yang, Z., Tschudi, M., von Segesser, L., Stulz, P., Boulanger, C., Siebenmann, R., Turina, M., Bühler, F.R. Circ. Res. (1990)
- Increased sensitivity of fibroblasts from amyotrophic lateral sclerosis patients to oxidative stress. Aguirre, T., Van Den Bosch, L., Goetschalckx, K., Tilkin, P., Mathijs, G., Cassiman, J.J., Robberecht, W. Ann. Neurol. (1998)
- Increased oxidative stress with aging reduces chondrocyte survival: correlation with intracellular glutathione levels. Carlo, M.D., Loeser, R.F. Arthritis Rheum. (2003)
- gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: physiological implications. Christen, S., Woodall, A.A., Shigenaga, M.K., Southwell-Keely, P.T., Duncan, M.W., Ames, B.N. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Glyceraldehyde-3-phosphate dehydrogenase is required for the transport of nitric oxide in platelets. McDonald, B., Reep, B., Lapetina, E.G., Molina y Vedia, L. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Metabolism of glyceryl trinitrate to nitric oxide by endothelial cells and smooth muscle cells and its induction by Escherichia coli lipopolysaccharide. Salvemini, D., Mollace, V., Pistelli, A., Anggard, E., Vane, J. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells. Li, M.H., Cha, Y.N., Surh, Y.J. Free Radic. Biol. Med. (2006)
- Nitric oxide and peroxynitrite promote complete disruption of the [4Fe-4S] cluster of recombinant human iron regulatory protein 1. Soum, E., Drapier, J.C. J. Biol. Inorg. Chem. (2003)
- In vitro inhibition of MAP kinase (ERK1/ERK2) activity by phosphorylated glia maturation factor (GMF). Zaheer, A., Lim, R. Biochemistry (1996)
- Protection from nicotinamide inhibition of interleukin-1 beta-induced RIN cell nitric oxide formation is associated with induction of MnSOD enzyme activity. Andrade, J., Conde, M., Ramírez, R., Monteseirín, J., Conde, J., Sobrino, F., Bedoya, F.J. Endocrinology (1996)
- Activation of MAP kinase-activated protein kinase 2 in human neutrophils after phorbol ester or fMLP peptide stimulation. Zu, Y.L., Ai, Y., Gilchrist, A., Labadia, M.E., Sha'afi, R.I., Huang, C.K. Blood (1996)
- Nitric oxide regulates shear stress-induced early growth response-1. Expression via the extracellular signal-regulated kinase pathway in endothelial cells. Chiu, J.J., Wung, B.S., Hsieh, H.J., Lo, L.W., Wang, D.L. Circ. Res. (1999)
- Ethanol metabolism alters interferon gamma signaling in recombinant HepG2 cells. Osna, N.A., Clemens, D.L., Donohue, T.M. Hepatology (2005)
- In vivo and in vitro apoptosis of human thymocytes are associated with nitrotyrosine formation. Moulian, N., Truffault, F., Gaudry-Talarmain, Y.M., Serraf, A., Berrih-Aknin, S. Blood (2001)
- Inactivation of NADP+-dependent isocitrate dehydrogenase by peroxynitrite. Implications for cytotoxicity and alcohol-induced liver injury. Lee, J.H., Yang, E.S., Park, J.W. J. Biol. Chem. (2003)