Gene Review:
KAT6A - K(lysine) acetyltransferase 6A
Homo sapiens
Synonyms:
Histone acetyltransferase KAT6A, MOZ, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3, MYST-3, MYST3, ...
Panagopoulos,
Fioretos,
Isaksson,
Samuelsson,
Billström,
Strömbeck,
Mitelman,
Johansson,
Rozman,
Camós,
Colomer,
Villamor,
Esteve,
Costa,
Carrió,
Aymerich,
Aguilar,
Domingo,
Solé,
Gomis,
Florensa,
Montserrat,
Campo,
Schmidt,
Strehl,
Thaler,
Strunk,
Sill,
Linkesch,
Jäger,
Sperr,
Greinix,
König,
Emberger,
Haas,
Imamura,
Kakazu,
Hibi,
Morimoto,
Fukushima,
Ijuin,
Hada,
Kitabayashi,
Abe,
Imashuku,
Katoh,
Katoh,
Panagopoulos,
Isaksson,
Lindvall,
Hagemeijer,
Mitelman,
Johansson,
- Identification and characterization of ASXL3 gene in silico. Katoh, M., Katoh, M. Int. J. Oncol. (2004)
- Acute mixed lineage leukemia with an inv(8)(p11q13) resulting in fusion of the genes for MOZ and TIF2. Liang, J., Prouty, L., Williams, B.J., Dayton, M.A., Blanchard, K.L. Blood (1998)
- A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia. Carapeti, M., Aguiar, R.C., Goldman, J.M., Cross, N.C. Blood (1998)
- Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13). Panagopoulos, I., Fioretos, T., Isaksson, M., Samuelsson, U., Billström, R., Strömbeck, B., Mitelman, F., Johansson, B. Hum. Mol. Genet. (2001)
- A further case of acute myelomonocytic leukemia with inv(8) chromosomal rearrangement and MOZ-NCOA2 gene fusion. Murati, A., Adélaïde, J., Popovici, C., Mozziconacci, M.J., Arnoulet, C., Lafage-Pochitaloff, M., Sainty, D., Birnbaum, D., Chaffanet, M. Int. J. Mol. Med. (2003)
- The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Borrow, J., Stanton, V.P., Andresen, J.M., Becher, R., Behm, F.G., Chaganti, R.S., Civin, C.I., Disteche, C., Dubé, I., Frischauf, A.M., Horsman, D., Mitelman, F., Volinia, S., Watmore, A.E., Housman, D.E. Nat. Genet. (1996)
- Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells. Thomas, T., Corcoran, L.M., Gugasyan, R., Dixon, M.P., Brodnicki, T., Nutt, S.L., Metcalf, D., Voss, A.K. Genes Dev. (2006)
- The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. John, S., Howe, L., Tafrov, S.T., Grant, P.A., Sternglanz, R., Workman, J.L. Genes Dev. (2000)
- Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein. Kitabayashi, I., Aikawa, Y., Nguyen, L.A., Yokoyama, A., Ohki, M. EMBO J. (2001)
- MOZ fusion proteins in acute myeloid leukaemia. Troke, P.J., Kindle, K.B., Collins, H.M., Heery, D.M. Biochem. Soc. Symp. (2006)
- MOZ-TIF2 alters cofactor recruitment and histone modification at the RARbeta2 promoter: differential effects of MOZ fusion proteins on CBP- and MOZ-dependent activators. Collins, H.M., Kindle, K.B., Matsuda, S., Ryan, C., Troke, P.J., Kalkhoven, E., Heery, D.M. J. Biol. Chem. (2006)
- MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2. Pelletier, N., Champagne, N., Stifani, S., Yang, X.J. Oncogene (2002)
- Abnormalities of chromosome band 8p11 in leukemia: two clinical syndromes can be distinguished on the basis of MOZ involvement. Aguiar, R.C., Chase, A., Coulthard, S., Macdonald, D.H., Carapeti, M., Reiter, A., Sohal, J., Lennard, A., Goldman, J.M., Cross, N.C. Blood (1997)
- moz regulates Hox expression and pharyngeal segmental identity in zebrafish. Miller, C.T., Maves, L., Kimmel, C.B. Development (2004)
- The monocytic leukemia zinc finger protein MOZ is a histone acetyltransferase. Champagne, N., Pelletier, N., Yang, X.J. Oncogene (2001)
- Transcriptional regulation of the human MIP-1alpha promoter by RUNX1 and MOZ. Bristow, C.A., Shore, P. Nucleic Acids Res. (2003)
- MOZ is fused to p300 in an acute monocytic leukemia with t(8;22). Chaffanet, M., Gressin, L., Preudhomme, C., Soenen-Cornu, V., Birnbaum, D., Pébusque, M.J. Genes Chromosomes Cancer (2000)
- Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein. Champagne, N., Bertos, N.R., Pelletier, N., Wang, A.H., Vezmar, M., Yang, Y., Heng, H.H., Yang, X.J. J. Biol. Chem. (1999)
- Rearrangement of the MOZ gene in pediatric therapy-related myelodysplastic syndrome with a novel chromosomal translocation t(2;8)(p23;p11). Imamura, T., Kakazu, N., Hibi, S., Morimoto, A., Fukushima, Y., Ijuin, I., Hada, S., Kitabayashi, I., Abe, T., Imashuku, S. Genes Chromosomes Cancer (2003)
- Type I MOZ/CBP (MYST3/CREBBP) is the most common chimeric transcript in acute myeloid leukemia with t(8;16)(p11;p13) translocation. Rozman, M., Camós, M., Colomer, D., Villamor, N., Esteve, J., Costa, D., Carrió, A., Aymerich, M., Aguilar, J.L., Domingo, A., Solé, F., Gomis, F., Florensa, L., Montserrat, E., Campo, E. Genes Chromosomes Cancer (2004)
- RT-PCR and FISH analysis of acute myeloid leukemia with t(8;16)(p11;p13) and chimeric MOZ and CBP transcripts: breakpoint cluster region and clinical implications. Schmidt, H.H., Strehl, S., Thaler, D., Strunk, D., Sill, H., Linkesch, W., Jäger, U., Sperr, W., Greinix, H.T., König, M., Emberger, W., Haas, O.A. Leukemia (2004)
- Genomic characterization of MOZ/CBP and CBP/MOZ chimeras in acute myeloid leukemia suggests the involvement of a damage-repair mechanism in the origin of the t(8;16)(p11;p13). Panagopoulos, I., Isaksson, M., Lindvall, C., Hagemeijer, A., Mitelman, F., Johansson, B. Genes Chromosomes Cancer (2003)