Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

MAP1LC3B - microtubule-associated protein 1 light...

Homo sapiens

Synonyms: ATG8F, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, LC3B, MAP1A/1BLC3, ...

He, H. et al., Tanida, I. et al.

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High impact information on MAP1LC3B

RNA interference of MAP1LC3B mRNA resulted in a decrease in both endogenous MAP1LC3B-PL and MAP1LC3B [1].
Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes [1].
Although MAP1LC3A and MAP1LC3C are produced by the proteolytic cleavage after the conserved C-terminal Gly residue, like their rat counterpart, MAP1LC3B does not undergo C-terminal cleavage and exists in a single modified form [2].
Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B [2].

References

Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes. Tanida, I., Ueno, T., Kominami, E. J. Biol. Chem. (2004)
Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. He, H., Dang, Y., Dai, F., Guo, Z., Wu, J., She, X., Pei, Y., Chen, Y., Ling, W., Wu, C., Zhao, S., Liu, J.O., Yu, L. J. Biol. Chem. (2003)

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MAP1LC3B - microtubule-associated protein 1 light...

Homo sapiens

High impact information on MAP1LC3B

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