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Gene Review: 

NRAMP4  -  metal transporter Nramp4

Arabidopsis thaliana

Synonyms: ARABIDOPSIS THALIANA NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 4, ATNRAMP4, At5g67330, AtNramp4, K8K14.5, ...
 
 
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High impact information on ATNRAMP4

  • In plants, AtNRAMP3 and AtNRAMP4 are induced under Fe deficiency [1].
  • The deduced amino acid sequences of the two Zip transporter genes (TjZnt1, TjZnt2) and one Nramp transporter gene cloned had high homologies with TcZNT1 and TcZNT2 of Thlaspi caerulescens and AtNRAMP4 of Arabidopsis thaliana, respectively, and were predicted as integral membrane proteins with 6 or 12 transmembrane domains [2].
 

Biological context of ATNRAMP4

  • The similitude of AtNRAMP3 and AtNRAMP4 expression patterns and their common targeting to the vacuole, together with the lack of obvious phenotype in nramp3-1 and nramp4-1 single knockout mutants, suggested a functional redundancy [1].

References

  1. Mobilization of vacuolar iron by AtNRAMP3 and AtNRAMP4 is essential for seed germination on low iron. Lanquar, V., Lelièvre, F., Bolte, S., Hamès, C., Alcon, C., Neumann, D., Vansuyt, G., Curie, C., Schröder, A., Krämer, U., Barbier-Brygoo, H., Thomine, S. EMBO J. (2005) [Pubmed]
  2. Cloning of three ZIP/Nramp transporter genes from a Ni hyperaccumulator plant Thlaspi japonicum and their Ni2+-transport abilities. Mizuno, T., Usui, K., Horie, K., Nosaka, S., Mizuno, N., Obata, H. Plant Physiol. Biochem. (2005) [Pubmed]
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