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Gene Review

ASB1  -  anthranilate synthase beta subunit 1

Arabidopsis thaliana

Synonyms: ANTHRANILATE SYNTHASE BETA SUBUNIT, F4F7.39, F4F7_39, TRP4, TRYPTOPHAN BIOSYNTHESIS 4, ...
 
 
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High impact information on ASB1

 

Biological context of ASB1

  • The trp4; trp1-100 double mutant does not segregate at expected frequencies in genetic crosses because of a female-specific defect in transmission of the double mutant genotype, suggesting a role for the tryptophan pathway in female gametophyte development [2].
 

Associations of ASB1 with chemical compounds

  • Together, these findings reveal that ASA1 and ASB1 are key elements in the regulation of auxin production and an unexpected node of interaction between ethylene responses and auxin biosynthesis in Arabidopsis [1].
  • Transgenic hairy roots expressing both trp5 and ASB1 show a significantly greater resistance to feedback inhibition of AS activity by tryptophan than plants expressing only trp5 [3].
  • When TDC is ectopically expressed together with trp5 and ASB1, the induced trp5:ASB1:TDC hairy root line accumulates tryptamine up to 14-fold higher than the uninduced line [3].
  • In an attempt to more successfully engineer the indole pathway, a wild type Arabidopsis ASbeta subunit (ASB1) cDNA was constitutively expressed along with the inducible expression of trp5 and TDC in C. roseus hairy roots [3].
 

Regulatory relationships of ASB1

References

 
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