Gene Review:
IRS4 - insulin receptor substrate 4
Homo sapiens
Synonyms:
160 kDa phosphotyrosine protein, IRS-4, Insulin receptor substrate 4, PY160, Phosphoprotein of 160 kDa, ...
- Interaction between Brk kinase and insulin receptor substrate-4. Qiu, H., Zappacosta, F., Su, W., Annan, R.S., Miller, W.T. Oncogene (2005)
- Candida albicans IRS4 contributes to hyphal formation and virulence after the initial stages of disseminated candidiasis. Badrane, H., Cheng, S., Nguyen, M.H., Jia, H.Y., Zhang, Z., Weisner, N., Clancy, C.J. Microbiology (Reading, Engl.) (2005)
- Genetic diversity of bacterial agents detected in ticks removed from asymptomatic patients in northeastern Italy. Sanogo, Y.O., Parola, P., Shpynov, S., Camicas, J.L., Brouqui, P., Caruso, G., Raoult, D. Ann. N. Y. Acad. Sci. (2003)
- Common amino acid substitutions in insulin receptor substrate-4 are not associated with Type II diabetes mellitus or insulin resistance. Almind, K., Frederiksen, S.K., Ahlgren, M.G., Urhammer, S., Hansen, T., Clausen, J.O., Pedersen, O. Diabetologia (1998)
- Differential roles of insulin receptor substrates in brown adipocyte differentiation. Tseng, Y.H., Kriauciunas, K.M., Kokkotou, E., Kahn, C.R. Mol. Cell. Biol. (2004)
- IRS-4 mediates protein kinase B signaling during insulin stimulation without promoting antiapoptosis. Uchida, T., Myers, M.G., White, M.F. Mol. Cell. Biol. (2000)
- Insulin receptor substrate-4 signaling in quiescent rat hepatocytes and in regenerating rat liver. Escribano, O., Fernández-Moreno, M.D., Zueco, J.A., Menor, C., Fueyo, J., Ropero, R.M., Diaz-Laviada, I., Román, I.D., Guijarro, L.G. Hepatology (2003)
- Insulin receptor substrate-4 is expressed in muscle tissue without acting as a substrate for the insulin receptor. Schreyer, S., Ledwig, D., Rakatzi, I., Klöting, I., Eckel, J. Endocrinology (2003)
- Phylogenetic analysis of spotted fever group rickettsiae based on gltA, 17-kDa, and rOmpA genes amplified by nested PCR from ticks in Japan. Ishikura, M., Ando, S., Shinagawa, Y., Matsuura, K., Hasegawa, S., Nakayama, T., Fujita, H., Watanabe, M. Microbiol. Immunol. (2003)
- Tyrosine phosphoproteomics of fibroblast growth factor signaling: a role for insulin receptor substrate-4. Hinsby, A.M., Olsen, J.V., Mann, M. J. Biol. Chem. (2004)
- A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family. Lavan, B.E., Fantin, V.R., Chang, E.T., Lane, W.S., Keller, S.R., Lienhard, G.E. J. Biol. Chem. (1997)
- Characterization of insulin receptor substrate 4 in human embryonic kidney 293 cells. Fantin, V.R., Sparling, J.D., Slot, J.W., Keller, S.R., Lienhard, G.E., Lavan, B.E. J. Biol. Chem. (1998)
- The insulin-like growth factor I receptor-induced interaction of insulin receptor substrate-4 and Crk-II. Karas, M., Koval, A.P., Zick, Y., LeRoith, D. Endocrinology (2001)
- Insulin receptor substrate polymorphisms and type 2 diabetes mellitus. Sesti, G. Pharmacogenomics (2000)
- Angiotensin II modulates tyr-phosphorylation of IRS-4, an insulin receptor substrate, in rat liver membranes. Villarreal, R.S., Alvarez, S.E., Ayub, M.J., Ciuffo, G.M. Mol. Cell. Biochem. (2006)
- Insulin receptor substrate 4 associates with the protein IRAS. Sano, H., Liu, S.C., Lane, W.S., Piletz, J.E., Lienhard, G.E. J. Biol. Chem. (2002)
- Action of insulin receptor substrate-3 (IRS-3) and IRS-4 to stimulate translocation of GLUT4 in rat adipose cells. Zhou, L., Chen, H., Xu, P., Cong, L.N., Sciacchitano, S., Li, Y., Graham, D., Jacobs, A.R., Taylor, S.I., Quon, M.J. Mol. Endocrinol. (1999)
- Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation. Mihindukulasuriya, K.A., Zhou, G., Qin, J., Tan, T.H. J. Biol. Chem. (2004)
- Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 gene. Fantin, V.R., Lavan, B.E., Wang, Q., Jenkins, N.A., Gilbert, D.J., Copeland, N.G., Keller, S.R., Lienhard, G.E. Endocrinology (1999)