Gene Review:
ERG27 - 3-keto-steroid reductase
Saccharomyces cerevisiae S288c
Synonyms:
YLR100W
- Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis. Mo, C., Valachovic, M., Randall, S.K., Nickels, J.T., Bard, M. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Characterization of the Saccharomyces cerevisiae ERG27 gene encoding the 3-keto reductase involved in C-4 sterol demethylation. Gachotte, D., Sen, S.E., Eckstein, J., Barbuch, R., Krieger, M., Ray, B.D., Bard, M. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis. Marijanovic, Z., Laubner, D., Moller, G., Gege, C., Husen, B., Adamski, J., Breitling, R. Mol. Endocrinol. (2003)
- In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity. Mo, C., Milla, P., Athenstaedt, K., Ott, R., Balliano, G., Daum, G., Bard, M. Biochim. Biophys. Acta (2003)
- Isolation, characterization, and regulation of the Candida albicans ERG27 gene encoding the sterol 3-keto reductase. Pierson, C.A., Jia, N., Mo, C., Lees, N.D., Sturm, A.M., Eckstein, J., Barbuct, R., Bard, M. Med. Mycol. (2004)
- The effect of the erg26-1 mutation on the regulation of lipid metabolism in Saccharomyces cerevisiae. Baudry, K., Swain, E., Rahier, A., Germann, M., Batta, A., Rondet, S., Mandala, S., Henry, K., Tint, G.S., Edlind, T., Kurtz, M., Nickels, J.T. J. Biol. Chem. (2001)
- 17beta-hydroxysteroid dehydrogenase type 7--an ancient 3-ketosteroid reductase of cholesterogenesis. Breitling, R., Krazeisen, A., Möller, G., Adamski, J. Mol. Cell. Endocrinol. (2001)
- 17Beta-hydroxysteroid dehydrogenase type 7 (Hsd17b7) reverts cholesterol auxotrophy in NS0 cells. Seth, G., McIvor, R.S., Hu, W.S. J. Biotechnol. (2006)