Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

RPS30A - Rps30ap

Saccharomyces cerevisiae S288c

Baker, R.T. et al., Davis, L. et al.

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High impact information on RPS30A

Genomic hybridization reveals that the RPS30A gene is duplicated [1].
Disruption of the RPS30A gene is not lethal but confers a slow growth phenotype [1].
RPS30A, which encodes ribosomal protein S30, was identified in a screen for high-copy suppressors of the dom34delta growth defect. dom34delta mutants display an altered polyribosome profile that is rescued by expression of RPS30A [2].

Analytical, diagnostic and therapeutic context of RPS30A

The corresponding gene was identified in the GenBankTM data base by sequence alignment and termed RPS30A [1].

References

The yeast homolog of mammalian ribosomal protein S30 is expressed from a duplicated gene without a ubiquitin-like protein fusion sequence. Evolutionary implications. Baker, R.T., Williamson, N.A., Wettenhall, R.E. J. Biol. Chem. (1996) [Pubmed]
Yeast dom34 mutants are defective in multiple developmental pathways and exhibit decreased levels of polyribosomes. Davis, L., Engebrecht, J. Genetics (1998) [Pubmed]

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