Gene Review:
CDC25 - Cdc25p
Saccharomyces cerevisiae S288c
Synonyms:
CTN1, Cell division control protein 25, L2142.6, YLR310C
- The C-terminal part of the CDC25 gene product has Ras-nucleotide exchange activity when present in a chimeric SDC25-CDC25 protein. Boy-Marcotte, E., Buu, A., Soustelle, C., Poullet, P., Parmeggiani, A., Jacquet, M. Curr. Genet. (1993)
- From structure to function: possible biological roles of a new widespread protein family binding hydrophobic ligands and displaying a nucleotide binding site. Schoentgen, F., Jollès, P. FEBS Lett. (1995)
- Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1. Chant, J., Corrado, K., Pringle, J.R., Herskowitz, I. Cell (1991)
- Functional cloning of BUD5, a CDC25-related gene from S. cerevisiae that can suppress a dominant-negative RAS2 mutant. Powers, S., Gonzales, E., Christensen, T., Cubert, J., Broek, D. Cell (1991)
- Dual regulation of meiosis in yeast. Malone, R.E. Cell (1990)
- The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Broek, D., Toda, T., Michaeli, T., Levin, L., Birchmeier, C., Zoller, M., Powers, S., Wigler, M. Cell (1987)
- CDC25: a component of the RAS-adenylate cyclase pathway in Saccharomyces cerevisiae. Robinson, L.C., Gibbs, J.B., Marshall, M.S., Sigal, I.S., Tatchell, K. Science (1987)
- In vitro reconstitution of cdc25 regulated S. cerevisiae adenylyl cyclase and its kinetic properties. Engelberg, D., Simchen, G., Levitzki, A. EMBO J. (1990)
- A new RAS mutation that suppresses the CDC25 gene requirement for growth of Saccharomyces cerevisiae. Camonis, J.H., Jacquet, M. Mol. Cell. Biol. (1988)
- Activation of adenylate cyclase in cdc25 mutants of Saccharomyces cerevisiae. Pardo, L.A., Lazo, P.S., Ramos, S. FEBS Lett. (1993)
- Homologous activators of ras in fission and budding yeast. Hughes, D.A., Fukui, Y., Yamamoto, M. Nature (1990)
- The COOH-domain of the product of the Saccharomyces cerevisiae SCD25 gene elicits activation of p21-ras proteins in mammalian cells. Rey, I., Schweighoffer, F., Barlat, I., Camonis, J., Boy-Marcotte, E., Guilbaud, R., Jacquet, M., Tocque, B. Oncogene (1991)
- Macromolecular syntheses in the cell cycle mutant cdc25 of budding yeast. Martegani, E., Vanoni, M., Baroni, M. Eur. J. Biochem. (1984)
- SDC25, a dispensable Ras guanine nucleotide exchange factor of Saccharomyces cerevisiae differs from CDC25 by its regulation. Boy-Marcotte, E., Ikonomi, P., Jacquet, M. Mol. Biol. Cell (1996)
- The Saccharomyces cerevisiae CDC25 gene product binds specifically to catalytically inactive ras proteins in vivo. Munder, T., Fürst, P. Mol. Cell. Biol. (1992)
- The SH3 domain of the S. cerevisiae Cdc25p binds adenylyl cyclase and facilitates Ras regulation of cAMP signalling. Mintzer, K.A., Field, J. Cell. Signal. (1999)
- Ssa1p chaperone interacts with the guanine nucleotide exchange factor of ras Cdc25p and controls the cAMP pathway in Saccharomyces cerevisiae. Geymonat, M., Wang, L., Garreau, H., Jacquet, M. Mol. Microbiol. (1998)
- The glyceraldehyde-3-phosphate dehydrogenase binds in vitro to the SH3 domain of Saccharomyces cerevisiae Cdc25p. Buu, A., Garreau, H., Jacquet, M. C. R. Acad. Sci. III, Sci. Vie (1995)
- Anti-Cdc25 antibodies inhibit guanyl nucleotide-dependent adenylyl cyclase of Saccharomyces cerevisiae and cross-react with a 150-kilodalton mammalian protein. Gross, E., Marbach, I., Engelberg, D., Segal, M., Simchen, G., Levitzki, A. Mol. Cell. Biol. (1992)
- SDC25, a CDC25-like gene which contains a RAS-activating domain and is a dispensable gene of Saccharomyces cerevisiae. Damak, F., Boy-Marcotte, E., Le-Roscouet, D., Guilbaud, R., Jacquet, M. Mol. Cell. Biol. (1991)
- TFS1: a suppressor of cdc25 mutations in Saccharomyces cerevisiae. Robinson, L.C., Tatchell, K. Mol. Gen. Genet. (1991)
- At acidic pH, the diminished hypoxic expression of the SRP1/TIR1 yeast gene depends on the GPA2-cAMP and HOG pathways. Bourdineaud, J.P. Res. Microbiol. (2000)
- Functional homology among human and fission yeast Cdc14 phosphatases. Vázquez-Novelle, M.D., Esteban, V., Bueno, A., Sacristán, M.P. J. Biol. Chem. (2005)
- MSI1, a negative regulator of the RAS-cAMP pathway in Saccharomyces cerevisiae. Ruggieri, R., Tanaka, K., Nakafuku, M., Kaziro, Y., Toh-e, A., Matsumoto, K. Proc. Natl. Acad. Sci. U.S.A. (1989)
- The yeast TEM1 gene, which encodes a GTP-binding protein, is involved in termination of M phase. Shirayama, M., Matsui, Y., Toh-E, A. Mol. Cell. Biol. (1994)
- Mapping of the Saccharomyces cerevisiae CDC3, CDC25, and CDC42 genes to chromosome XII by chromosome blotting and tetrad analysis. Johnson, D.I., Jacobs, C.W., Pringle, J.R., Robinson, L.C., Carle, G.F., Olson, M.V. Yeast (1987)
- Mutagenic alteration of the distal switch II region of RAS blocks CDC25-dependent signaling functions. Mirisola, M.G., Seidita, G., Verrotti, A.C., Di Blasi, F., Fasano, O. J. Biol. Chem. (1994)
- Characterization, cloning and sequence analysis of the CDC25 gene which controls the cyclic AMP level of Saccharomyces cerevisiae. Camonis, J.H., Kalékine, M., Gondré, B., Garreau, H., Boy-Marcotte, E., Jacquet, M. EMBO J. (1986)
- Site-directed mutagenesis of the Saccharomyces cerevisiae CDC25 gene: effects on mitotic growth and cAMP signalling. Schomerus, C., Munder, T., Küntzel, H. Mol. Gen. Genet. (1990)