Gene Review:
KIN28 - TFIIH complex serine/threonine-protein...
Saccharomyces cerevisiae S288c
Synonyms:
D2330, Serine/threonine-protein kinase KIN28, YDL108W
- Gene loops juxtapose promoters and terminators in yeast. O'Sullivan, J.M., Tan-Wong, S.M., Morillon, A., Lee, B., Coles, J., Mellor, J., Proudfoot, N.J. Nat. Genet. (2004)
- Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme. Kuras, L., Struhl, K. Nature (1999)
- Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo. Lee, D., Lis, J.T. Nature (1998)
- KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity. Cismowski, M.J., Laff, G.M., Solomon, M.J., Reed, S.I. Mol. Cell. Biol. (1995)
- The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD. Valay, J.G., Simon, M., Dubois, M.F., Bensaude, O., Facca, C., Faye, G. J. Mol. Biol. (1995)
- A transcriptional autoregulatory loop for KIN28-CCL1 and SRB10-SRB11, each encoding RNA polymerase II CTD kinase-cyclin pair, stimulates the meiotic development of S. cerevisiae. Ohkuni, K., Yamashita, I. Yeast (2000)
- KIN28, a yeast split gene coding for a putative protein kinase homologous to CDC28. Simon, M., Seraphin, B., Faye, G. EMBO J. (1986)
- Two cyclin-dependent kinases promote RNA polymerase II transcription and formation of the scaffold complex. Liu, Y., Kung, C., Fishburn, J., Ansari, A.Z., Shokat, K.M., Hahn, S. Mol. Cell. Biol. (2004)
- Histone H2B ubiquitylation is associated with elongating RNA polymerase II. Xiao, T., Kao, C.F., Krogan, N.J., Sun, Z.W., Greenblatt, J.F., Osley, M.A., Strahl, B.D. Mol. Cell. Biol. (2005)
- Mutual targeting of mediator and the TFIIH kinase Kin28. Guidi, B.W., Bjornsdottir, G., Hopkins, D.C., Lacomis, L., Erdjument-Bromage, H., Tempst, P., Myers, L.C. J. Biol. Chem. (2004)
- Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors. Krakowiak, A., Pace, H.C., Blackburn, G.M., Adams, M., Mekhalfia, A., Kaczmarek, R., Baraniak, J., Stec, W.J., Brenner, C. J. Biol. Chem. (2004)
- Ccl1, a cyclin associated with protein kinase Kin28, controls the phosphorylation of RNA polymerase II largest subunit and mRNA transcription. Valay, J.G., Dubois, M.F., Bensaude, O., Faye, G. C. R. Acad. Sci. III, Sci. Vie (1996)
- Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast. Ganem, C., Devaux, F., Torchet, C., Jacq, C., Quevillon-Cheruel, S., Labesse, G., Facca, C., Faye, G. EMBO J. (2003)
- Cak1 is required for Kin28 phosphorylation and activation in vivo. Espinoza, F.H., Farrell, A., Nourse, J.L., Chamberlin, H.M., Gileadi, O., Morgan, D.O. Mol. Cell. Biol. (1998)
- Activating phosphorylation of the Kin28p subunit of yeast TFIIH by Cak1p. Kimmelman, J., Kaldis, P., Hengartner, C.J., Laff, G.M., Koh, S.S., Young, R.A., Solomon, M.J. Mol. Cell. Biol. (1999)