Gene Review:
GCD6 - Gcd6p
Saccharomyces cerevisiae S288c
Synonyms:
GCD complex subunit GCD6, Guanine nucleotide exchange factor subunit GCD6, TIF225, Translation initiation factor eIF-2B subunit epsilon, YD8142.12, ...
- eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange. Pavitt, G.D., Ramaiah, K.V., Kimball, S.R., Hinnebusch, A.G. Genes Dev. (1998)
- Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation. Gomez, E., Mohammad, S.S., Pavitt, G.D. EMBO J. (2002)
- Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae. Bushman, J.L., Asuru, A.I., Matts, R.L., Hinnebusch, A.G. Mol. Cell. Biol. (1993)
- Multidomain organization of eukaryotic guanine nucleotide exchange translation initiation factor eIF-2B subunits revealed by analysis of conserved sequence motifs. Koonin, E.V. Protein Sci. (1995)
- Cloning and characterization of complementary and genomic DNAs encoding the epsilon-subunit of rat translation initiation factor-2B. Flowers, K.M., Mellor, H., Matts, R.L., Kimball, S.R., Jefferson, L.S. Biochim. Biophys. Acta (1996)