Gene Review:
GAL1 - galactokinase
Saccharomyces cerevisiae S288c
Synonyms:
Galactokinase, Galactose kinase, YBR020W, YBR0302
- Yeast regulatory gene GAL3: carbon regulation; UASGal elements in common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; encoded protein strikingly similar to yeast and Escherichia coli galactokinases. Bajwa, W., Torchia, T.E., Hopper, J.E. Mol. Cell. Biol. (1988)
- Highly efficient transactivation by the yeast Kluyveromyces lactis transcription factor LAC9 and its inhibition by the negative regulator GAL80 in mammalian cells. Schulz, W.A., Ebling, B., Hasse, A., Zenke, F., Breunig, K. Biol. Chem. Hoppe-Seyler (1993)
- Structure of RNA polymerase II promoters. Conformational alterations and template properties of circularized Saccharomyces cerevisiae GAL1-GAL10 divergent promoters. Camilloni, G., Della Seta, F., Negri, R., Grazia Ficca, A., Di Mauro, E. EMBO J. (1986)
- Cyclic AMP signaling is required for function of the N-terminal and CR1 domains of adenovirus E1A in Saccharomyces cerevisiae. Miller, M.E., Engel, D.A., Smith, M.M. Oncogene (1995)
- Use of a restriction endonuclease cytotoxicity assay to identify inducible GAL1 promoter variants with reduced basal activity. Lewis, L.K., Lobachev, K., Westmoreland, J.W., Karthikeyan, G., Williamson, K.M., Jordan, J.J., Resnick, M.A. Gene (2005)
- Gene loops juxtapose promoters and terminators in yeast. O'Sullivan, J.M., Tan-Wong, S.M., Morillon, A., Lee, B., Coles, J., Mellor, J., Proudfoot, N.J. Nat. Genet. (2004)
- Global role for chromatin remodeling enzymes in mitotic gene expression. Krebs, J.E., Fry, C.J., Samuels, M.L., Peterson, C.L. Cell (2000)
- Histone H2A.Z regulats transcription and is partially redundant with nucleosome remodeling complexes. Santisteban, M.S., Kalashnikova, T., Smith, M.M. Cell (2000)
- A subthreshold level of DNA topoisomerases leads to the excision of yeast rDNA as extrachromosomal rings. Kim, R.A., Wang, J.C. Cell (1989)
- Supercoiling of intracellular DNA can occur in eukaryotic cells. Giaever, G.N., Wang, J.C. Cell (1988)
- Expression and glycosylation of the respiratory syncytial virus G protein in Saccharomyces cerevisiae. Ding, M.X., Wen, D.Z., Schlesinger, M.J., Wertz, G.W., Ball, L.A. Virology (1987)
- Expression of the yeast galactokinase gene in Escherichia coli. Citron, B.A., Feiss, M., Donelson, J.E. Gene (1979)
- Cloning and expression of the yeast galactokinase gene in an Escherichia coli plasmid. Schell, M.A., Wilson, D.B. Gene (1979)
- Quenching accumulation of toxic galactose-1-phosphate as a system to select disruption of protein-protein interactions in vivo. Gunde, T., Tanner, S., Auf der Maur, A., Petrascheck, M., Barberis, A. BioTechniques (2004)
- GAL1-GAL10 divergent promoter region of Saccharomyces cerevisiae contains negative control elements in addition to functionally separate and possibly overlapping upstream activating sequences. West, R.W., Chen, S.M., Putz, H., Butler, G., Banerjee, M. Genes Dev. (1987)
- The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4. Larschan, E., Winston, F. Genes Dev. (2001)
- Cell signaling can direct either binary or graded transcriptional responses. Biggar, S.R., Crabtree, G.R. EMBO J. (2001)
- Increasing the rate of chromatin remodeling and gene activation--a novel role for the histone acetyltransferase Gcn5. Barbaric, S., Walker, J., Schmid, A., Svejstrup, J.Q., Hörz, W. EMBO J. (2001)
- Galactokinase encoded by GAL1 is a bifunctional protein required for induction of the GAL genes in Kluyveromyces lactis and is able to suppress the gal3 phenotype in Saccharomyces cerevisiae. Meyer, J., Walker-Jonah, A., Hollenberg, C.P. Mol. Cell. Biol. (1991)
- GAL4/GAL80-dependent nucleosome disruption/deposition on the upstream regions of the yeast GAL1-10 and GAL80 genes. Lohr, D., Lopez, J. J. Biol. Chem. (1995)
- In vitro reconstitution of intercompartmental protein transport to the yeast vacuole. Vida, T.A., Graham, T.R., Emr, S.D. J. Cell Biol. (1990)
- Yeast calmodulin and a conserved nuclear protein participate in the in vivo binding of a matrix association region. Fishel, B.R., Sperry, A.O., Garrard, W.T. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Dominant-lethal alpha-tubulin mutants defective in microtubule depolymerization in yeast. Anders, K.R., Botstein, D. Mol. Biol. Cell (2001)
- The product of the Saccharomyces cerevisiae RSS1 gene, identified as a high-copy suppressor of the rat7-1 temperature-sensitive allele of the RAT7/NUP159 nucleoporin, is required for efficient mRNA export. Del Priore, V., Snay, C.A., Bahr, A., Cole, C.N. Mol. Biol. Cell (1996)
- Specific DNA binding of GAL4, a positive regulatory protein of yeast. Giniger, E., Varnum, S.M., Ptashne, M. Cell (1985)
- Rad25p, a DNA helicase subunit of yeast transcription factor TFIIH, is required for promoter escape in vivo. Ostapenko, D., Gileadi, O. Gene (2000)
- Characteristics of Saccharomyces cerevisiae gal1 Delta and gal1 Delta hxk2 Delta mutants expressing recombinant proteins from the GAL promoter. Kang, H.A., Kang, W.K., Go, S.M., Rezaee, A., Krishna, S.H., Rhee, S.K., Kim, J.Y. Biotechnol. Bioeng. (2005)
- In vivo DNA-binding properties of a yeast transcription activator protein. Selleck, S.B., Majors, J.E. Mol. Cell. Biol. (1987)
- Gal3p and Gal1p interact with the transcriptional repressor Gal80p to form a complex of 1:1 stoichiometry. Timson, D.J., Ross, H.C., Reece, R.J. Biochem. J. (2002)
- Analysis of the GAL3 signal transduction pathway activating GAL4 protein-dependent transcription in Saccharomyces cerevisiae. Bhat, P.J., Oh, D., Hopper, J.E. Genetics (1990)
- Yeast HMG proteins NHP6A/B potentiate promoter-specific transcriptional activation in vivo and assembly of preinitiation complexes in vitro. Paull, T.T., Carey, M., Johnson, R.C. Genes Dev. (1996)
- Multiple copies of MRG19 suppress transcription of the GAL1 promoter in a GAL80-dependent manner in Saccharomyces cerevisiae. Kabir, M.A., Khanday, F.A., Mehta, D.V., Bhat, P.J. Mol. Gen. Genet. (2000)
- The yeast NOP4 gene product is an essential nucleolar protein required for pre-rRNA processing and accumulation of 60S ribosomal subunits. Sun, C., Woolford, J.L. EMBO J. (1994)
- Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo. Mann, R.K., Grunstein, M. EMBO J. (1992)
- Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repression. Griggs, D.W., Johnston, M. Proc. Natl. Acad. Sci. U.S.A. (1991)
- The insertion of two amino acids into a transcriptional inducer converts it into a galactokinase. Platt, A., Ross, H.C., Hankin, S., Reece, R.J. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Unusual aspects of in vitro RNA processing in the 3' regions of the GAL1, GAL7, and GAL10 genes in Saccharomyces cerevisiae. Sadhale, P.P., Platt, T. Mol. Cell. Biol. (1992)
- HPR1 encodes a global positive regulator of transcription in Saccharomyces cerevisiae. Zhu, Y., Peterson, C.L., Christman, M.F. Mol. Cell. Biol. (1995)
- The Regulatory Roles of the Galactose Permease and Kinase in the Induction Response of the GAL Network in Saccharomyces cerevisiae. Hawkins, K.M., Smolke, C.D. J. Biol. Chem. (2006)
- Unique distribution of GAL genes on chromosome XI in the yeast Saccharomyces naganishii. Kodama, T., Hisatomi, T., Kakiuchi, M., Aya, R., Yoshida, K., Bando, Y., Takami, T., Tsuboi, M. Curr. Microbiol. (2003)
- Galactose induction in yeast involves association of Gal80p with Gal1p or Gal3p. Vollenbroich, V., Meyer, J., Engels, R., Cardinali, G., Menezes, R.A., Hollenberg, C.P. Mol. Gen. Genet. (1999)
- The Saccharomyces cerevisiae Srb8-Srb11 complex functions with the SAGA complex during Gal4-activated transcription. Larschan, E., Winston, F. Mol. Cell. Biol. (2005)