Gene Review:
PAF1 - Paf1p
Saccharomyces cerevisiae S288c
Synonyms:
Protein PAF1, RNA polymerase II-associated protein 1, YBR2016, YBR279W
- A posttranscriptional role for the yeast Paf1-RNA polymerase II complex is revealed by identification of primary targets. Penheiter, K.L., Washburn, T.M., Porter, S.E., Hoffman, M.G., Jaehning, J.A. Mol. Cell (2005)
- A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formation. Sheldon, K.E., Mauger, D.M., Arndt, K.M. Mol. Cell (2005)
- The Paf1 complex has functions independent of actively transcribing RNA polymerase II. Mueller, C.L., Porter, S.E., Hoffman, M.G., Jaehning, J.A. Mol. Cell (2004)
- The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Krogan, N.J., Dover, J., Wood, A., Schneider, J., Heidt, J., Boateng, M.A., Dean, K., Ryan, O.W., Golshani, A., Johnston, M., Greenblatt, J.F., Shilatifard, A. Mol. Cell (2003)
- Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex. Mueller, C.L., Jaehning, J.A. Mol. Cell. Biol. (2002)
- A novel collection of accessory factors associated with yeast RNA polymerase II. Wade, P.A., Werel, W., Fentzke, R.C., Thompson, N.E., Leykam, J.F., Burgess, R.R., Jaehning, J.A., Burton, Z.F. Protein Expr. Purif. (1996)
- A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling. Chang, M., French-Cornay, D., Fan, H.Y., Klein, H., Denis, C.L., Jaehning, J.A. Mol. Cell. Biol. (1999)
- Paf1p, an RNA polymerase II-associated factor in Saccharomyces cerevisiae, may have both positive and negative roles in transcription. Shi, X., Finkelstein, A., Wolf, A.J., Wade, P.A., Burton, Z.F., Jaehning, J.A. Mol. Cell. Biol. (1996)
- Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism. Betz, J.L., Chang, M., Washburn, T.M., Porter, S.E., Mueller, C.L., Jaehning, J.A. Mol. Genet. Genomics (2002)
- The yeast pafl-rNA polymerase II complex is required for full expression of a subset of cell cycle-regulated genes. Porter, S.E., Washburn, T.M., Chang, M., Jaehning, J.A. Eukaryotic Cell (2002)
- Mutations in the PAY5 gene of the yeast Yarrowia lipolytica cause the accumulation of multiple subpopulations of peroxisomes. Titorenko, V.I., Eitzen, G.A., Rachubinski, R.A. J. Biol. Chem. (1996)
- The Paf1 complex physically and functionally associates with transcription elongation factors in vivo. Squazzo, S.L., Costa, P.J., Lindstrom, D.L., Kumer, K.E., Simic, R., Jennings, J.L., Link, A.J., Arndt, K.M., Hartzog, G.A. EMBO J. (2002)
- Exchange of RNA polymerase II initiation and elongation factors during gene expression in vivo. Pokholok, D.K., Hannett, N.M., Young, R.A. Mol. Cell (2002)
- The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p. Wood, A., Schneider, J., Dover, J., Johnston, M., Shilatifard, A. J. Biol. Chem. (2003)
- The Spt4p subunit of yeast DSIF stimulates association of the Paf1 complex with elongating RNA polymerase II. Qiu, H., Hu, C., Wong, C.M., Hinnebusch, A.G. Mol. Cell. Biol. (2006)
- Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme. Shi, X., Chang, M., Wolf, A.J., Chang, C.H., Frazer-Abel, A.A., Wade, P.A., Burton, Z.F., Jaehning, J.A. Mol. Cell. Biol. (1997)
- Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization. Porter, S.E., Penheiter, K.L., Jaehning, J.A. Eukaryotic Cell (2005)
- Histone trimethylation by Set1 is coordinated by the RRM, autoinhibitory, and catalytic domains. Schlichter, A., Cairns, B.R. EMBO J. (2005)