Gene Review:
SPT23 - Spt23p
Saccharomyces cerevisiae S288c
Synonyms:
Protein SPT23, YKL020C
- Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone. Rape, M., Hoppe, T., Gorr, I., Kalocay, M., Richly, H., Jentsch, S. Cell (2001)
- Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing. Hoppe, T., Matuschewski, K., Rape, M., Schlenker, S., Ulrich, H.D., Jentsch, S. Cell (2000)
- MGA2 is involved in the low-oxygen response element-dependent hypoxic induction of genes in Saccharomyces cerevisiae. Jiang, Y., Vasconcelles, M.J., Wretzel, S., Light, A., Martin, C.E., Goldberg, M.A. Mol. Cell. Biol. (2001)
- Genetic redundancy between SPT23 and MGA2: regulators of Ty-induced mutations and Ty1 transcription in Saccharomyces cerevisiae. Zhang, S., Burkett, T.J., Yamashita, I., Garfinkel, D.J. Mol. Cell. Biol. (1997)
- MGA2 and SPT23 are modifiers of transcriptional silencing in yeast. Dula, M.L., Holmes, S.G. Genetics (2000)
- MGA2 or SPT23 is required for transcription of the delta9 fatty acid desaturase gene, OLE1, and nuclear membrane integrity in Saccharomyces cerevisiae. Zhang, S., Skalsky, Y., Garfinkel, D.J. Genetics (1999)
- Molecular characterization of the SPT23 gene: a dosage-dependent suppressor of Ty-induced promoter mutations from Saccharomyces cerevisiae. Burkett, T.J., Garfinkel, D.J. Yeast (1994)
- The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Hitchcock, A.L., Krebber, H., Frietze, S., Lin, A., Latterich, M., Silver, P.A. Mol. Biol. Cell (2001)
- Rsp5p is required for ER bound Mga2p120 polyubiquitination and release of the processed/tethered transactivator Mga2p90. Shcherbik, N., Zoladek, T., Nickels, J.T., Haines, D.S. Curr. Biol. (2003)
- A single PXY motif located within the carboxyl terminus of Spt23p and Mga2p mediates a physical and functional interaction with ubiquitin ligase Rsp5p. Shcherbik, N., Kee, Y., Lyon, N., Huibregtse, J.M., Haines, D.S. J. Biol. Chem. (2004)
- Regulation of long chain unsaturated fatty acid synthesis in yeast. Martin, C.E., Oh, C.S., Jiang, Y. Biochim. Biophys. Acta (2007)