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SNF8  -  Snf8p

Saccharomyces cerevisiae S288c

Synonyms: ESCRT-II complex subunit VPS22, VPL14, VPS22, Vacuolar protein-sorting-associated protein 22, Vacuolar-sorting protein SNF8, ...
 
 
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High impact information on SNF8

  • These findings suggest that SNF7 and SNF8 are functionally related [1].
  • Mutations in the SNF8 gene impair derepression of the SUC2 gene, encoding invertase, in response to glucose limitation of Saccharomyces cerevisiae [1].
  • Mutations of SNF8 and SNF7 showed similar phenotypes and genetic interactions, and the double mutant combination caused no additional phenotypic impairment [1].
  • Arginine-83 of yeast Vps25p involved in Vps22p interaction was highly, but not absolutely, conserved [2].
  • Residues in two amino-terminal PPXY motifs (motif I and II), involved in dimerization of Vps25p and interaction with Vps22p and Vps36p, were closely, but not absolutely conserved [2].

References

  1. Molecular analysis of the SNF8 gene of Saccharomyces cerevisiae. Yeghiayan, P., Tu, J., Vallier, L.G., Carlson, M. Yeast (1995) [Pubmed]
  2. Genetic structure and evolution of the Vps25 family, a yeast ESCRT-II component. Slater, R., Bishop, N.E. BMC Evol. Biol. (2006) [Pubmed]
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