Gene Review:
TNKS - tankyrase, TRF1-interacting ankyrin...
Homo sapiens
Synonyms:
ADP-ribosyltransferase diphtheria toxin-like 5, ARTD5, PARP-5a, PARP5A, PARPL, ...
- Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1. Deng, Z., Atanasiu, C., Zhao, K., Marmorstein, R., Sbodio, J.I., Chi, N.W., Lieberman, P.M. J. Virol. (2005)
- Novel tankyrase-related gene detected with meningioma-specific sera. Monz, D., Munnia, A., Comtesse, N., Fischer, U., Steudel, W.I., Feiden, W., Glass, B., Meese, E.U. Clin. Cancer Res. (2001)
- Cloning and characterization of TNKL, a member of tankyrase gene family. Kuimov, A.N., Kuprash, D.V., Petrov, V.N., Vdovichenko, K.K., Scanlan, M.J., Jongeneel, C.V., Lagarkova, M.A., Nedospasov, S.A. Genes Immun. (2001)
- Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma. Shervington, A., Patel, R., Lu, C., Cruickshanks, N., Lea, R., Roberts, G., Dawson, T., Shervington, L. Brain Res. (2007)
- Achieving healthy weight in African-American communities: research perspectives and priorities. Kumanyika, S.K., Gary, T.L., Lancaster, K.J., Samuel-Hodge, C.D., Banks-Wallace, J., Beech, B.M., Hughes-Halbert, C., Karanja, N., Odoms-Young, A.M., Prewitt, T.E., Whitt-Glover, M.C. Obes. Res. (2005)
- TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex. Ye, J.Z., de Lange, T. Nat. Genet. (2004)
- Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Smith, S., Giriat, I., Schmitt, A., de Lange, T. Science (1998)
- TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression. Kaminker, P.G., Kim, S.H., Taylor, R.D., Zebarjadian, Y., Funk, W.D., Morin, G.B., Yaswen, P., Campisi, J. J. Biol. Chem. (2001)
- Tankyrase-1 overexpression reduces genotoxin-induced cell death by inhibiting PARP1. Yeh, T.Y., Sbodio, J.I., Nguyen, M.T., Meyer, T.N., Lee, R.M., Chi, N.W. Mol. Cell. Biochem. (2005)
- Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles. Chi, N.W., Lodish, H.F. J. Biol. Chem. (2000)
- Cell cycle dependent localization of the telomeric PARP, tankyrase, to nuclear pore complexes and centrosomes. Smith, S., de Lange, T. J. Cell. Sci. (1999)
- Mitotic phosphorylation of tankyrase, a PARP that promotes spindle assembly, by GSK3. Yeh, T.Y., Sbodio, J.I., Chi, N.W. Biochem. Biophys. Res. Commun. (2006)
- Tankyrase, a positive regulator of telomere elongation, is over expressed in human breast cancer. Gelmini, S., Poggesi, M., Distante, V., Bianchi, S., Simi, L., Luconi, M., Raggi, C.C., Cataliotti, L., Pazzagli, M., Orlando, C. Cancer Lett. (2004)
- Changes in GABAB modulation during a theta cycle may be analogous to the fall of temperature during annealing. Sohal, V.S., Hasselmo, M.E. Neural computation. (1998)
- Spectroelectrochemical sensing based on multimode selectivity simultaneously achievable in a single device. 11. Design and evaluation of a small portable sensor for the determination of ferrocyanide in Hanford waste samples. Stegemiller, M.L., Heineman, W.R., Seliskar, C.J., Ridgway, T.H., Bryan, S.A., Hubler, T., Sell, R.L. Environ. Sci. Technol. (2003)
- The formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenance. Fuchs, U., Rehkamp, G.F., Slany, R., Follo, M., Borkhardt, A. FEBS Lett. (2003)
- The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182). Seimiya, H., Smith, S. J. Biol. Chem. (2002)
- Protection of internal (TTAGGG)n repeats in Chinese hamster cells by telomeric protein TRF1. Krutilina, R.I., Smirnova, A.N., Mudrak, O.S., Pleskach, N.M., Svetlova, M.P., Oei, S.L., Yau, P.M., Bradbury, E.M., Zalensky, A.O., Tomilin, N.V. Oncogene (2003)
- Antisense inhibition of Bcr-Abl/c-Abl synthesis promotes telomerase activity and upregulates tankyrase in human leukemia cells. Bakalova, R., Ohba, H., Zhelev, Z., Kubo, T., Fujii, M., Ishikawa, M., Shinohara, Y., Baba, Y. FEBS Lett. (2004)
- Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner. Sbodio, J.I., Chi, N.W. J. Biol. Chem. (2002)
- Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14. Lyons, R.J., Deane, R., Lynch, D.K., Ye, Z.S., Sanderson, G.M., Eyre, H.J., Sutherland, G.R., Daly, R.J. J. Biol. Chem. (2001)
- NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis. Chang, W., Dynek, J.N., Smith, S. Biochem. J. (2005)
- Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres. Cook, B.D., Dynek, J.N., Chang, W., Shostak, G., Smith, S. Mol. Cell. Biol. (2002)
- Identification of a novel gene (ADPRTL1) encoding a potential Poly(ADP-ribosyl)transferase protein. Still, I.H., Vince, P., Cowell, J.K. Genomics (1999)