Gene Review:
CRADD - CASP2 and RIPK1 domain containing adaptor...
Homo sapiens
Synonyms:
Caspase and RIP adapter with death domain, Death domain-containing protein CRADD, MRT34, RAIDD, RIP-associated protein with a death domain
- Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment. Chou, J.J., Matsuo, H., Duan, H., Wagner, G. Cell (1998)
- RAIDD is a new 'death' adaptor molecule. Duan, H., Dixit, V.M. Nature (1997)
- Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction. Zhou, P., Chou, J., Olea, R.S., Yuan, J., Wagner, G. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Subcellular localization and CARD-dependent oligomerization of the death adaptor RAIDD. Shearwin-Whyatt, L.M., Harvey, N.L., Kumar, S. Cell Death Differ. (2000)
- CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP. Ahmad, M., Srinivasula, S.M., Wang, L., Talanian, R.V., Litwack, G., Fernandes-Alnemri, T., Alnemri, E.S. Cancer Res. (1997)
- Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria. Guo, Y., Srinivasula, S.M., Druilhe, A., Fernandes-Alnemri, T., Alnemri, E.S. J. Biol. Chem. (2002)
- Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage. Vakifahmetoglu, H., Olsson, M., Orrenius, S., Zhivotovsky, B. Oncogene (2006)
- Thermodynamics and stability of the PAAD/DAPIN/PYRIN domain of IFI-16. Dalal, K., Pio, F. FEBS Lett. (2006)
- Crystal structure of RAIDD death domain implicates potential mechanism of PIDDosome assembly. Park, H.H., Wu, H. J. Mol. Biol. (2006)
- Identification of CARDIAK, a RIP-like kinase that associates with caspase-1. Thome, M., Hofmann, K., Burns, K., Martinon, F., Bodmer, J.L., Mattmann, C., Tschopp, J. Curr. Biol. (1998)
- The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress. Tinel, A., Tschopp, J. Science (2004)
- Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1. Day, C.L., Dupont, C., Lackmann, M., Vaux, D.L., Hinds, M.G. Cell Death Differ. (1999)
- Identification of novel genes with prognostic value in childhood leukemia using cDNA microarray and quantitative RT-PCR. Hattori, H., Matsuzaki, A., Suminoe, A., Koga, Y., Tashiro, K., Hara, T. Pediatric hematology and oncology. (2006)
- Direct physical interaction between the Caenorhabditis elegans 'death proteins' CED-3 and CED-4. Irmler, M., Hofmann, K., Vaux, D., Tschopp, J. FEBS Lett. (1997)