Gene Review:
TNFRSF14 - tumor necrosis factor receptor superfamily...
Homo sapiens
Synonyms:
ATAR, CD270, HVEA, HVEM, Herpes virus entry mediator A, ...
Gentz,
Ni,
Lyn,
Cordoba,
Tan,
Whitbeck,
Ponce de Leon,
Ikeuchi,
Wang,
Truneh,
Baribaud,
Itoh,
Xu,
Lou,
Eisenberg,
Suzuki,
Campadelli-Fiume,
McCaughan,
Colombero,
Menotti,
Solovyev,
Krummenacher,
Baribaud,
Young,
Eisenberg,
Miki,
Katayama,
Seth,
Ochiai,
Elliott,
Kita,
Lopez,
Kim,
Okajima,
Kim,
Yu,
Silverman,
Kwon,
Kelley,
Ponce de Leon,
Hsu,
Fukushima,
Cohen,
Lee,
Harrop,
Shibata,
Cohen,
Haber,
Cocchi,
Porter,
Boyle,
Whitbeck,
Noguchi,
Oh,
Bender,
Gorrell,
- Tumor necrosis factor receptor and ligand superfamily family members TNFRSF14 and LIGHT: new players in human atherogenesis. Bobik, A., Kalinina, N. Arterioscler. Thromb. Vasc. Biol. (2001)
- Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway. Cheung, T.C., Humphreys, I.R., Potter, K.G., Norris, P.S., Shumway, H.M., Tran, B.R., Patterson, G., Jean-Jacques, R., Yoon, M., Spear, P.G., Murphy, K.M., Lurain, N.S., Benedict, C.A., Ware, C.F. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus. Krummenacher, C., Baribaud, F., Ponce de Leon, M., Baribaud, I., Whitbeck, J.C., Xu, R., Cohen, G.H., Eisenberg, R.J. Virology (2004)
- LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator. Mauri, D.N., Ebner, R., Montgomery, R.I., Kochel, K.D., Cheung, T.C., Yu, G.L., Ruben, S., Murphy, M., Eisenberg, R.J., Cohen, G.H., Spear, P.G., Ware, C.F. Immunity (1998)
- Dual transforming activities of the FUS (TLS)-ERG leukemia fusion protein conferred by two N-terminal domains of FUS (TLS). Ichikawa, H., Shimizu, K., Katsu, R., Ohki, M. Mol. Cell. Biol. (1999)
- Tomoregulin-2 is found extensively in plaques in Alzheimer's disease brain. Siegel, D.A., Davies, P., Dobrenis, K., Huang, M. J. Neurochem. (2006)
- The Fly CAMTA Transcription Factor Potentiates Deactivation of Rhodopsin, a G Protein-Coupled Light Receptor. Han, J., Gong, P., Reddig, K., Mitra, M., Guo, P., Li, H.S. Cell (2006)
- Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family. Montgomery, R.I., Warner, M.S., Lum, B.J., Spear, P.G. Cell (1996)
- AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection. Summerford, C., Bartlett, J.S., Samulski, R.J. Nat. Med. (1999)
- Mutations in the N termini of herpes simplex virus type 1 and 2 gDs alter functional interactions with the entry/fusion receptors HVEM, nectin-2, and 3-O-sulfated heparan sulfate but not with nectin-1. Yoon, M., Zago, A., Shukla, D., Spear, P.G. J. Virol. (2003)
- Monoclonal antibodies to distinct sites on herpes simplex virus (HSV) glycoprotein D block HSV binding to HVEM. Nicola, A.V., Ponce de Leon, M., Xu, R., Hou, W., Whitbeck, J.C., Krummenacher, C., Montgomery, R.I., Spear, P.G., Eisenberg, R.J., Cohen, G.H. J. Virol. (1998)
- Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1. Marsters, S.A., Ayres, T.M., Skubatch, M., Gray, C.L., Rothe, M., Ashkenazi, A. J. Biol. Chem. (1997)
- A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis. Yu, K.Y., Kwon, B., Ni, J., Zhai, Y., Ebner, R., Kwon, B.S. J. Biol. Chem. (1999)
- LIGHT is involved in the pathogenesis of rheumatoid arthritis by inducing the expression of pro-inflammatory cytokines and MMP-9 in macrophages. Kim, W.J., Kang, Y.J., Koh, E.M., Ahn, K.S., Cha, H.S., Lee, W.H. Immunology (2005)
- Modulation of T-cell responses to alloantigens by TR6/DcR3. Zhang, J., Salcedo, T.W., Wan, X., Ullrich, S., Hu, B., Gregorio, T., Feng, P., Qi, S., Chen, H., Cho, Y.H., Li, Y., Moore, P.A., Wu, J. J. Clin. Invest. (2001)
- Proinflammatory effects of LIGHT through HVEM and LTbetaR interactions in cultured human umbilical vein endothelial cells. Chang, Y.H., Hsieh, S.L., Chao, Y., Chou, Y.C., Lin, W.W. J. Biomed. Sci. (2005)
- Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry. Bender, F.C., Whitbeck, J.C., Ponce de Leon, M., Lou, H., Eisenberg, R.J., Cohen, G.H. J. Virol. (2003)
- Mutations in herpes simplex virus glycoprotein D that prevent cell entry via nectins and alter cell tropism. Manoj, S., Jogger, C.R., Myscofski, D., Yoon, M., Spear, P.G. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Attenuating lymphocyte activity: the crystal structure of the BTLA-HVEM complex. Compaan, D.M., Gonzalez, L.C., Tom, I., Loyet, K.M., Eaton, D., Hymowitz, S.G. J. Biol. Chem. (2005)
- Fate Determination of the Flavin Photoreceptions in the Cyanobacterial Blue Light Receptor TePixD (Tll0078). Okajima, K., Fukushima, Y., Suzuki, H., Kita, A., Ochiai, Y., Katayama, M., Shibata, Y., Miki, K., Noguchi, T., Itoh, S., Ikeuchi, M. J. Mol. Biol. (2006)
- High voltage immunoelectron microscopy of complement receptor type 3-mediated capping and internalization of group A streptococcal cell walls by human neutrophils. Pryzwansky, K.B. Microsc. Res. Tech. (1994)
- HVEM signaling in monocytes is mediated by intracellular calcium mobilization. Heo, S.K., Yoon, M.A., Lee, S.C., Ju, S.A., Choi, J.H., Suh, P.G., Kwon, B.S., Kim, B.S. J. Immunol. (2007)
- Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth. Harrop, J.A., McDonnell, P.C., Brigham-Burke, M., Lyn, S.D., Minton, J., Tan, K.B., Dede, K., Spampanato, J., Silverman, C., Hensley, P., DiPrinzio, R., Emery, J.G., Deen, K., Eichman, C., Chabot-Fletcher, M., Truneh, A., Young, P.R. J. Biol. Chem. (1998)
- Tumor necrosis factor receptor superfamily 14 is involved in atherogenesis by inducing proinflammatory cytokines and matrix metalloproteinases. Lee, W.H., Kim, S.H., Lee, Y., Lee, B.B., Kwon, B., Song, H., Kwon, B.S., Park, J.E. Arterioscler. Thromb. Vasc. Biol. (2001)
- Induction of caspase 8 by interferon gamma renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB. Yang, X., Merchant, M.S., Romero, M.E., Tsokos, M., Wexler, L.H., Kontny, U., Mackall, C.L., Thiele, C.J. Cancer Res. (2003)
- ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5. Hsu, H., Solovyev, I., Colombero, A., Elliott, R., Kelley, M., Boyle, W.J. J. Biol. Chem. (1997)
- The novel receptors that mediate the entry of herpes simplex viruses and animal alphaherpesviruses into cells. Campadelli-Fiume, G., Cocchi, F., Menotti, L., Lopez, M. Rev. Med. Virol. (2000)
- Intrahepatic gene expression in human alcoholic hepatitis. Seth, D., Gorrell, M.D., Cordoba, S., McCaughan, G.W., Haber, P.S. J. Hepatol. (2006)
- A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation. Kwon, B.S., Tan, K.B., Ni, J., Oh, K.O., Lee, Z.H., Kim, K.K., Kim, Y.J., Wang, S., Gentz, R., Yu, G.L., Harrop, J., Lyn, S.D., Silverman, C., Porter, T.G., Truneh, A., Young, P.R. J. Biol. Chem. (1997)
- Kinetic analysis of glycoprotein C of herpes simplex virus types 1 and 2 binding to heparin, heparan sulfate, and complement component C3b. Rux, A.H., Lou, H., Lambris, J.D., Friedman, H.M., Eisenberg, R.J., Cohen, G.H. Virology (2002)
- Overexpression of CIN85 suppresses the growth of herpes simplex virus in HeLa cells. Narita, T., Ando, A., Mikami, Y., Taniyama, T. Exp. Cell Res. (2005)