Gene Review:
virF - transcriptional activator of virulence loci
Shigella flexneri 5a str. M90T
- Thermoregulation of Shigella and Escherichia coli EIEC pathogenicity. A temperature-dependent structural transition of DNA modulates accessibility of virF promoter to transcriptional repressor H-NS. Falconi, M., Colonna, B., Prosseda, G., Micheli, G., Gualerzi, C.O. EMBO J. (1998)
- Cloning of regions required for contact hemolysis and entry into LLC-MK2 cells from Shigella sonnei form I plasmid: virF is a positive regulator gene for these phenotypes. Kato, J., Ito, K., Nakamura, A., Watanabe, H. Infect. Immun. (1989)
- The virF promoter in Shigella: more than just a curved DNA stretch. Prosseda, G., Falconi, M., Giangrossi, M., Gualerzi, C.O., Micheli, G., Colonna, B. Mol. Microbiol. (2004)
- Putrescine or a combination of methionine and arginine restores virulence gene expression in a tRNA modification-deficient mutant of Shigella flexneri: a possible role in adaptation of virulence. Durand, J.M., Björk, G.R. Mol. Microbiol. (2003)
- Spontaneous insertion of an IS1-like element into the virF gene is responsible for avirulence in opaque colonial variants of Shigella flexneri 2a. Mills, J.A., Venkatesan, M.M., Baron, L.S., Buysse, J.M. Infect. Immun. (1992)
- DNA sequence and product analysis of the virF locus responsible for congo red binding and cell invasion in Shigella flexneri 2a. Sakai, T., Sasakawa, C., Makino, S., Yoshikawa, M. Infect. Immun. (1986)
- Expression of four virulence antigens of Shigella flexneri is positively regulated at the transcriptional level by the 30 kiloDalton virF protein. Sakai, T., Sasakawa, C., Yoshikawa, M. Mol. Microbiol. (1988)
- Virulence plasmid instability in Shigella flexneri 2a is induced by virulence gene expression. Schuch, R., Maurelli, A.T. Infect. Immun. (1997)
- A role for H-NS in the regulation of the virF gene of Shigella and enteroinvasive Escherichia coli. Prosseda, G., Fradiani, P.A., Di Lorenzo, M., Falconi, M., Micheli, G., Casalino, M., Nicoletti, M., Colonna, B. Res. Microbiol. (1998)
- A dual transcriptional activation system for the 230 kb plasmid genes coding for virulence-associated antigens of Shigella flexneri. Adler, B., Sasakawa, C., Tobe, T., Makino, S., Komatsu, K., Yoshikawa, M. Mol. Microbiol. (1989)
- Molecular genetic approaches to the pathogenesis of bacillary dysentery. Yoshikawa, M., Sasakawa, C., Makino, S., Okada, N., Lett, M.C., Sakai, T., Yamada, M., Komatsu, K., Kamata, K., Kurata, T. Microbiol. Sci. (1988)
- In vivo DNA-binding and oligomerization properties of the Shigella flexneri AraC-like transcriptional regulator VirF as identified by random and site-specific mutagenesis. Porter, M.E., Dorman, C.J. J. Bacteriol. (2002)