Gene Review:
DNAJA3 - DnaJ (Hsp40) homolog, subfamily A, member 3
Homo sapiens
Synonyms:
DnaJ homolog subfamily A member 3, mitochondrial, DnaJ protein Tid-1, HCA57, Hepatocellular carcinoma-associated antigen 57, TID1, ...
- Molecular mechanism of hTid-1, the human homolog of Drosophila tumor suppressor l(2)Tid, in the regulation of NF-kappaB activity and suppression of tumor growth. Cheng, H., Cenciarelli, C., Nelkin, G., Tsan, R., Fan, D., Cheng-Mayer, C., Fidler, I.J. Mol. Cell. Biol. (2005)
- Tid1 negatively regulates the migratory potential of cancer cells by inhibiting the production of interleukin-8. Kim, S.W., Hayashi, M., Lo, J.F., Fearns, C., Xiang, R., Lazennec, G., Yang, Y., Lee, J.D. Cancer Res. (2005)
- HTLV-1 Tax-associated hTid-1, a human DnaJ protein, is a repressor of Ikappa B kinase beta subunit. Cheng, H., Cenciarelli, C., Tao, M., Parks, W.P., Cheng-Mayer, C. J. Biol. Chem. (2002)
- Human T cell leukemia virus type 1 Tax associates with a molecular chaperone complex containing hTid-1 and Hsp70. Cheng, H., Cenciarelli, C., Shao, Z., Vidal, M., Parks, W.P., Pagano, M., Cheng-Mayer, C. Curr. Biol. (2001)
- The human DnaJ protein, hTid-1, enhances binding of a multimer of the herpes simplex virus type 1 UL9 protein to oris, an origin of viral DNA replication. Eom, C.Y., Lehman, I.R. Proc. Natl. Acad. Sci. U.S.A. (2002)
- TID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functions. Syken, J., De-Medina, T., Münger, K. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival. Lo, J.F., Hayashi, M., Woo-Kim, S., Tian, B., Huang, J.F., Fearns, C., Takayama, S., Zapata, J.M., Yang, Y., Lee, J.D. Mol. Cell. Biol. (2004)
- Genomic organization and expression of the human tumorous imaginal disc (TID1) gene. Yin, X., Rozakis-Adcock, M. Gene (2001)
- Human tumorous imaginal disc 1 (TID1) associates with Trk receptor tyrosine kinases and regulates neurite outgrowth in nnr5-TrkA cells. Liu, H.Y., MacDonald, J.I., Hryciw, T., Li, C., Meakin, S.O. J. Biol. Chem. (2005)
- Depletion of physiological levels of the human TID1 protein renders cancer cell lines resistant to apoptosis mediated by multiple exogenous stimuli. Edwards, K.M., Münger, K. Oncogene (2004)
- Negative regulation of hepatitis B virus replication by cellular Hsp40/DnaJ proteins through destabilization of viral core and X proteins. Sohn, S.Y., Kim, S.B., Kim, J., Ahn, B.Y. J. Gen. Virol. (2006)
- hTid-1, a human DnaJ protein, modulates the interferon signaling pathway. Sarkar, S., Pollack, B.P., Lin, K.T., Kotenko, S.V., Cook, J.R., Lewis, A., Pestka, S. J. Biol. Chem. (2001)
- Tid1, the human homologue of a Drosophila tumor suppressor, reduces the malignant activity of ErbB-2 in carcinoma cells. Kim, S.W., Chao, T.H., Xiang, R., Lo, J.F., Campbell, M.J., Fearns, C., Lee, J.D. Cancer Res. (2004)
- Effects of expression of hRFI on adenoma formation and tumor progression in colorectal adenoma-carcinoma sequence. Sasaki, S., Watanabe, T., Konishi, T., Kitayama, J., Nagawa, H. J. Exp. Clin. Cancer Res. (2004)
- Sister chromatid cohesion remodeling and meiotic recombination. Kateneva, A.V., Dresser, M.E. Cell Cycle (2006)
- Turnover of hepatitis B virus X protein is facilitated by Hdj1, a human Hsp40/DnaJ protein. Sohn, S.Y., Kim, J.H., Baek, K.W., Ryu, W.S., Ahn, B.Y. Biochem. Biophys. Res. Commun. (2006)