Gene Review:
ATG12 - autophagy related 12
Homo sapiens
Synonyms:
APG12, APG12-like, APG12L, Autophagy-related protein 12, FBR93, ...
- ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. Kouroku, Y., Fujita, E., Tanida, I., Ueno, T., Isoai, A., Kumagai, H., Ogawa, S., Kaufman, R.J., Kominami, E., Momoi, T. Cell Death Differ. (2007)
- A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy. Mizushima, N., Sugita, H., Yoshimori, T., Ohsumi, Y. J. Biol. Chem. (1998)
- Role of the Apg12 conjugation system in mammalian autophagy. Mizushima, N., Yoshimori, T., Ohsumi, Y. Int. J. Biochem. Cell Biol. (2003)
- Mammalian Apg12p, but not the Apg12p.Apg5p conjugate, facilitates LC3 processing. Tanida, I., Nishitani, T., Nemoto, T., Ueno, T., Kominami, E. Biochem. Biophys. Res. Commun. (2002)
- Structure-Function Relationship of Atg12, a Ubiquitin-like Modifier Essential for Autophagy. Hanada, T., Ohsumi, Y. Autophagy. (2005)
- Stimulation of ATG12-ATG5 Conjugation by Ribonucleic Acid. Shao, Y., Gao, Z., Feldman, T., Jiang, X. Autophagy (2007)
- The Crystal Structure of Plant ATG12 and its Biological Implication in Autophagy. Suzuki, N.N., Yoshimoto, K., Fujioka, Y., Ohsumi, Y., Inagaki, F. Autophagy. (2005)