Gene Review:
katG - catalase-peroxidase
Mycobacterium tuberculosis CDC1551
- Association between Mycobacterium tuberculosis Beijing/W Lineage Strain Infection and Extrathoracic Tuberculosis: Insights from Epidemiologic and Clinical Characterization of the Three Principal Genetic Groups of M. tuberculosis Clinical Isolates. Kong, Y., Cave, M.D., Zhang, L., Foxman, B., Marrs, C.F., Bates, J.H., Yang, Z.H. J. Clin. Microbiol. (2007)
- Detection of Multidrug Resistance in Mycobacterium tuberculosis. Sekiguchi, J., Miyoshi-Akiyama, T., Augustynowicz-Kopec, E., Zwolska, Z., Kirikae, F., Toyota, E., Kobayashi, I., Morita, K., Kudo, K., Kato, S., Kuratsuji, T., Mori, T., Kirikae, T. J. Clin. Microbiol. (2007)
- Mycobacterial catalase-peroxidase is a tissue antigen and target of the adaptive immune response in systemic sarcoidosis. Song, Z., Marzilli, L., Greenlee, B.M., Chen, E.S., Silver, R.F., Askin, F.B., Teirstein, A.S., Zhang, Y., Cotter, R.J., Moller, D.R. J. Exp. Med. (2005)
- Structural characterization of the Ser324Thr variant of the catalase-peroxidase (KatG) from Burkholderia pseudomallei. Deemagarn, T., Carpena, X., Singh, R., Wiseman, B., Fita, I., Loewen, P.C. J. Mol. Biol. (2005)
- Compensatory functions of two alkyl hydroperoxide reductases in the oxidative defense system of Legionella pneumophila. LeBlanc, J.J., Davidson, R.J., Hoffman, P.S. J. Bacteriol. (2006)
- The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis. Zhang, Y., Heym, B., Allen, B., Young, D., Cole, S. Nature (1992)
- Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis. DeBarber, A.E., Mdluli, K., Bosman, M., Bekker, L.G., Barry, C.E. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Analysis of heme structural heterogeneity in Mycobacterium tuberculosis catalase-peroxidase (KatG). Chouchane, S., Girotto, S., Kapetanaki, S., Schelvis, J.P., Yu, S., Magliozzo, R.S. J. Biol. Chem. (2003)
- Reduced affinity for Isoniazid in the S315T mutant of Mycobacterium tuberculosis KatG is a key factor in antibiotic resistance. Yu, S., Girotto, S., Lee, C., Magliozzo, R.S. J. Biol. Chem. (2003)
- Purification and characterization of recombinant catalase-peroxidase, which confers isoniazid sensitivity in Mycobacterium tuberculosis. Nagy, J.M., Cass, A.E., Brown, K.A. J. Biol. Chem. (1997)
- Performance of the Genotype MTBDR Line Probe Assay for Detection of Resistance to Rifampin and Isoniazid in Strains of Mycobacterium tuberculosis with Low- and High-Level Resistance. Brossier, F., Veziris, N., Truffot-Pernot, C., Jarlier, V., Sougakoff, W. J. Clin. Microbiol. (2006)
- Public health impact of isoniazid-resistant Mycobacterium tuberculosis strains with a mutation at amino-acid position 315 of katG: a decade of experience in The Netherlands. van Doorn, H.R., de Haas, P.E., Kremer, K., Vandenbroucke-Grauls, C.M., Borgdorff, M.W., van Soolingen, D. Clin. Microbiol. Infect. (2006)
- Hydrogen peroxide-mediated isoniazid activation catalyzed by Mycobacterium tuberculosis catalase-peroxidase (KatG) and its S315T mutant. Zhao, X., Yu, H., Yu, S., Wang, F., Sacchettini, J.C., Magliozzo, R.S. Biochemistry (2006)
- Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis. Rouse, D.A., Li, Z., Bai, G.H., Morris, S.L. Antimicrob. Agents Chemother. (1995)
- Resonance Raman spectroscopy of Compound II and its decay in Mycobacterium tuberculosis catalase-peroxidase KatG and its isoniazid resistant mutant S315T. Kapetanaki, S.M., Chouchane, S., Yu, S., Magliozzo, R.S., Schelvis, J.P. J. Inorg. Biochem. (2005)
- Evaluation of the Genotype MTBDR assay for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis isolates. Cavusoglu, C., Turhan, A., Akinci, P., Soyler, I. J. Clin. Microbiol. (2006)
- Isoniazid's Bactericidal Activity Ceases because of the Emergence of Resistance, Not Depletion of Mycobacterium tuberculosis in the Log Phase of Growth. Gumbo, T., Louie, A., Liu, W., Ambrose, P.G., Bhavnani, S.M., Brown, D., Drusano, G.L. J. Infect. Dis. (2007)
- Use of a mycobacteriophage-based assay for rapid assessment of susceptibilities of Mycobacterium tuberculosis isolates to isoniazid and influence of resistance level on assay performance. Galí, N., Domínguez, J., Blanco, S., Prat, C., Alcaide, F., Coll, P., Ausina, V. J. Clin. Microbiol. (2006)
- Systematic molecular characterization of multidrug-resistant Mycobacterium tuberculosis complex isolates from Spain. Samper, S., Iglesias, M.J., Rabanaque, M.J., Gómez, L.I., Lafoz, M.C., Jiménez, M.S., Ortega, A., Lezcano, M.A., Van Soolingen, D., Martín, C. J. Clin. Microbiol. (2005)
- Role of KatG catalase-peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst. Ng, V.H., Cox, J.S., Sousa, A.O., MacMicking, J.D., McKinney, J.D. Mol. Microbiol. (2004)
- Expression of katG in Mycobacterium tuberculosis is associated with its growth and persistence in mice and guinea pigs. Li, Z., Kelley, C., Collins, F., Rouse, D., Morris, S. J. Infect. Dis. (1998)
- Mutations prevalent among rifampin- and isoniazid-resistant Mycobacterium tuberculosis isolates from a hospital in Vietnam. Caws, M., Duy, P.M., Tho, D.Q., Lan, N.T., Hoa, D.V., Farrar, J. J. Clin. Microbiol. (2006)
- Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid. Argyrou, A., Vetting, M.W., Aladegbami, B., Blanchard, J.S. Nat. Struct. Mol. Biol. (2006)
- Population genetics study of isoniazid resistance mutations and evolution of multidrug-resistant Mycobacterium tuberculosis. Hazbón, M.H., Brimacombe, M., Bobadilla del Valle, M., Cavatore, M., Guerrero, M.I., Varma-Basil, M., Billman-Jacobe, H., Lavender, C., Fyfe, J., García-García, L., León, C.I., Bose, M., Chaves, F., Murray, M., Eisenach, K.D., Sifuentes-Osornio, J., Cave, M.D., Ponce de León, A., Alland, D. Antimicrob. Agents Chemother. (2006)
- Molecular characterization of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis from the USA. Guo, H., Seet, Q., Denkin, S., Parsons, L., Zhang, Y. J. Med. Microbiol. (2006)
- Mycobacterium tuberculosis catalase and peroxidase activities and resistance to oxidative killing in human monocytes in vitro. Manca, C., Paul, S., Barry, C.E., Freedman, V.H., Kaplan, G. Infect. Immun. (1999)
- Molecular analysis of Mycobacterium tuberculosis DNA from a family of 18th century Hungarians. Fletcher, H.A., Donoghue, H.D., Taylor, G.M., van der Zanden, A.G., Spigelman, M. Microbiology (Reading, Engl.) (2003)
- Analysis of the oxyR-ahpC region in isoniazid-resistant and -susceptible Mycobacterium tuberculosis complex organisms recovered from diseased humans and animals in diverse localities. Sreevatsan, S., Pan, X., Zhang, Y., Deretic, V., Musser, J.M. Antimicrob. Agents Chemother. (1997)
- Rapid genotypic detection of rifampin- and isoniazid-resistant Mycobacterium tuberculosis directly in clinical specimens. Bang, D., Bengård Andersen, A., Thomsen, V.Ø. J. Clin. Microbiol. (2006)
- Microarray and allele specific PCR detection of point mutations in Mycobacterium tuberculosis genes associated with drug resistance. Tang, X., Morris, S.L., Langone, J.J., Bockstahler, L.E. J. Microbiol. Methods (2005)
- Improving bacteriological diagnosis of tuberculosis. Wattal, C. Indian journal of pediatrics. (2002)
- Modulation of the activities of catalase-peroxidase HPI of Escherichia coli by site-directed mutagenesis. Hillar, A., Peters, B., Pauls, R., Loboda, A., Zhang, H., Mauk, A.G., Loewen, P.C. Biochemistry (2000)
- Conformational differences in Mycobacterium tuberculosis catalase-peroxidase KatG and its S315T mutant revealed by resonance Raman spectroscopy. Kapetanaki, S., Chouchane, S., Girotto, S., Yu, S., Magliozzo, R.S., Schelvis, J.P. Biochemistry (2003)