Gene Review:
TJP2 - tight junction protein 2
Homo sapiens
Synonyms:
C9DUPq21.11, DFNA51, DUP9q21.11, PFIC4, Tight junction protein 2, ...
- Organization and expression of the human zo-2 gene (tjp-2) in normal and neoplastic tissues. Chlenski, A., Ketels, K.V., Korovaitseva, G.I., Talamonti, M.S., Oyasu, R., Scarpelli, D.G. Biochim. Biophys. Acta (2000)
- Altered expression of ZO-1 and ZO-2 in sertoli cells and loss of blood-testis barrier integrity in testicular carcinoma in situ. Fink, C., Weigel, R., Hembes, T., Lauke-Wettwer, H., Kliesch, S., Bergmann, M., Brehm, R.H. Neoplasia (2006)
- Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT. Carlton, V.E., Harris, B.Z., Puffenberger, E.G., Batta, A.K., Knisely, A.S., Robinson, D.L., Strauss, K.A., Shneider, B.L., Lim, W.A., Salen, G., Morton, D.H., Bull, L.N. Nat. Genet. (2003)
- Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. Itoh, M., Furuse, M., Morita, K., Kubota, K., Saitou, M., Tsukita, S. J. Cell Biol. (1999)
- Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein. Jesaitis, L.A., Goodenough, D.A. J. Cell Biol. (1994)
- Developmental regulation of claudin localization by fetal alveolar epithelial cells. Daugherty, B.L., Mateescu, M., Patel, A.S., Wade, K., Kimura, S., Gonzales, L.W., Guttentag, S., Ballard, P.L., Koval, M. Am. J. Physiol. Lung Cell Mol. Physiol. (2004)
- In vitro protein complex formation with cytoskeleton-anchoring domain of occludin identified by limited proteolysis. Peng, B.H., Lee, J.C., Campbell, G.A. J. Biol. Chem. (2003)
- Nuclear localization of the tight junction protein ZO-2 in epithelial cells. Islas, S., Vega, J., Ponce, L., González-Mariscal, L. Exp. Cell Res. (2002)
- Protein-binding domains of the tight junction protein, ZO-2, are highly conserved between avian and mammalian species. Collins, J.R., Rizzolo, L.J. Biochem. Biophys. Res. Commun. (1998)
- The Friedreich ataxia critical region spans a 150-kb interval on chromosome 9q13. Montermini, L., Rodius, F., Pianese, L., Moltò, M.D., Cossée, M., Campuzano, V., Cavalcanti, F., Monticelli, A., Palau, F., Gyapay, G. Am. J. Hum. Genet. (1995)
- Interferon-beta counteracts inflammatory mediator-induced effects on brain endothelial cell tight junction molecules-implications for multiple sclerosis. Kuruganti, P.A., Hinojoza, J.R., Eaton, M.J., Ehmann, U.K., Sobel, R.A. J. Neuropathol. Exp. Neurol. (2002)
- Tight junction protein ZO-2 is differentially expressed in normal pancreatic ducts compared to human pancreatic adenocarcinoma. Chlenski, A., Ketels, K.V., Tsao, M.S., Talamonti, M.S., Anderson, M.R., Oyasu, R., Scarpelli, D.G. Int. J. Cancer (1999)
- The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B. Traweger, A., Fuchs, R., Krizbai, I.A., Weiger, T.M., Bauer, H.C., Bauer, H. J. Biol. Chem. (2003)
- Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and alpha catenin. Itoh, M., Morita, K., Tsukita, S. J. Biol. Chem. (1999)
- Regulation of cellular and molecular trafficking across human brain endothelial cells by Th1- and Th2-polarized lymphocytes. Biernacki, K., Prat, A., Blain, M., Antel, J.P. J. Neuropathol. Exp. Neurol. (2004)
- The tight junction protein ZO-2 contains three PDZ (PSD-95/Discs-Large/ZO-1) domains and an alternatively spliced region. Beatch, M., Jesaitis, L.A., Gallin, W.J., Goodenough, D.A., Stevenson, B.R. J. Biol. Chem. (1996)
- Epidermal growth factor induces tyrosine phosphorylation and reorganization of the tight junction protein ZO-1 in A431 cells. Van Itallie, C.M., Balda, M.S., Anderson, J.M. J. Cell. Sci. (1995)
- Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins. Tsukamoto, T., Nigam, S.K. Am. J. Physiol. (1999)
- Association of ARVCF with zonula occludens (ZO)-1 and ZO-2: binding to PDZ-domain proteins and cell-cell adhesion regulate plasma membrane and nuclear localization of ARVCF. Kausalya, P.J., Phua, D.C., Hunziker, W. Mol. Biol. Cell (2004)
- Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3. Wittchen, E.S., Haskins, J., Stevenson, B.R. J. Biol. Chem. (1999)
- Characterization of the interaction between protein 4.1R and ZO-2. A possible link between the tight junction and the actin cytoskeleton. Mattagajasingh, S.N., Huang, S.C., Hartenstein, J.S., Benz, E.J. J. Biol. Chem. (2000)
- Roles of ZO-1, occludin, and actin in oxidant-induced barrier disruption. Musch, M.W., Walsh-Reitz, M.M., Chang, E.B. Am. J. Physiol. Gastrointest. Liver Physiol. (2006)
- Molecular structure and assembly of the tight junction. Denker, B.M., Nigam, S.K. Am. J. Physiol. (1998)
- Analysis of tight junctions during neutrophil transendothelial migration. Burns, A.R., Bowden, R.A., MacDonell, S.D., Walker, D.C., Odebunmi, T.O., Donnachie, E.M., Simon, S.I., Entman, M.L., Smith, C.W. J. Cell. Sci. (2000)