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Gene Review: 

ydeO  -  transcriptional activator for mdtEF

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1493, JW1494
 
 
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High impact information on ydeO

  • This acid resistance is partially abolished by deletion of ydeP, yhiE or ydeO, genes induced by EvgA overexpression [1].
  • The first class contains seven operons induced by EvgA overexpression in the absence of ydeO, an AraC/XylS regulator gene [1].
  • The induction of mdtEF by GlcNAc is not mediated by the evgSA, ydeO, gadX, and rpoS signaling pathways that have been known to regulate mdtEF expression [2].
 

Biological context of ydeO

  • Operons in the second class were induced by EvgA overexpression only in the presence of ydeO [1].

References

  1. Regulatory network of acid resistance genes in Escherichia coli. Masuda, N., Church, G.M. Mol. Microbiol. (2003) [Pubmed]
  2. N-acetyl-d-glucosamine induces the expression of multidrug exporter genes, mdtEF, via catabolite activation in Escherichia coli. Hirakawa, H., Inazumi, Y., Senda, Y., Kobayashi, A., Hirata, T., Nishino, K., Yamaguchi, A. J. Bacteriol. (2006) [Pubmed]
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