Gene Review:
parE - DNA topoisomerase IV, subunit B
Escherichia coli str. K-12 substr. MG1655
Synonyms:
ECK3021, JW2998, nfxD
- Quinolone resistance locus nfxD of Escherichia coli is a mutant allele of the parE gene encoding a subunit of topoisomerase IV. Breines, D.M., Ouabdesselam, S., Ng, E.Y., Tankovic, J., Shah, S., Soussy, C.J., Hooper, D.C. Antimicrob. Agents Chemother. (1997)
- Escherichia coli topoisomerase IV. Purification, characterization, subunit structure, and subunit interactions. Peng, H., Marians, K.J. J. Biol. Chem. (1993)
- Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: role in fluoroquinolone resistance. Pan, X.S., Fisher, L.M. J. Bacteriol. (1996)
- Molecular characterization of the Salmonella typhimurium parE gene. Springer, A.L., Schmid, M.B. Nucleic Acids Res. (1993)
- Requirement of topoisomerase IV parC and parE genes for cell cycle progression and developmental regulation in Caulobacter crescentus. Ward, D., Newton, A. Mol. Microbiol. (1997)
- New topoisomerase essential for chromosome segregation in E. coli. Kato, J., Nishimura, Y., Imamura, R., Niki, H., Hiraga, S., Suzuki, H. Cell (1990)
- Alteration of Escherichia coli topoisomerase IV to novobiocin resistance. Hardy, C.D., Cozzarelli, N.R. Antimicrob. Agents Chemother. (2003)
- Analysis of the mutations involved in fluoroquinolone resistance of in vivo and in vitro mutants of Escherichia coli. Bachoual, R., Tankovic, J., Soussy, C.J. Microb. Drug Resist. (1998)
- Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals. Everett, M.J., Jin, Y.F., Ricci, V., Piddock, L.J. Antimicrob. Agents Chemother. (1996)
- Topoisomerase III can serve as the cellular decatenase in Escherichia coli. Nurse, P., Levine, C., Hassing, H., Marians, K.J. J. Biol. Chem. (2003)
- Limitations of plasmid complementation test for determination of quinolone resistance due to changes in the gyrase A protein and identification of conditional quinolone resistance locus. Soussy, C.J., Wolfson, J.S., Ng, E.Y., Hooper, D.C. Antimicrob. Agents Chemother. (1993)
- The region of the parE gene, homologous to the quinolone-resistant determining region of the gyrB gene, is not linked with the acquisition of quinolone resistance in Escherichia coli clinical isolates. Ruiz, J., Casellas, S., Jimenez de Anta, M.T., Vila, J. J. Antimicrob. Chemother. (1997)
- Molecular basis of quinolone resistance in Escherichia coli from wild birds. Jiménez Gómez, P.A., García de los Rios, J.E., Rojas Mendoza, A., de Pedro Ramonet, P., García Albiach, R., Reche Sainz, M.P. Can. J. Vet. Res. (2004)