Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

rhaB - rhamnulokinase

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3897, JW3875

Moralejo, P. et al., Wilms, B. et al.

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Disease relevance of rhaB

The sequencing of the EcoRI-HindIII fragment complementing mutations in the structural genes of the L-rhamnose regulon of Escherichia coli has permitted identification of the open reading frames corresponding to rhaB, rhaA, and rhaD [1].

High impact information on rhaB

The rhaB transcription start site was mapped to -24 relative to the start of translation [1].
Consumption of the inducer L-rhamnose was inhibited by inactivation of L-rhamnulose kinase encoding gene rhaB of Escherichia coli W3110, responsible for the first irreversible step in rhamnose catabolism [2].

References

Sequencing and characterization of a gene cluster encoding the enzymes for L-rhamnose metabolism in Escherichia coli. Moralejo, P., Egan, S.M., Hidalgo, E., Aguilar, J. J. Bacteriol. (1993) [Pubmed]
High-cell-density fermentation for production of L-N-carbamoylase using an expression system based on the Escherichia coli rhaBAD promoter. Wilms, B., Hauck, A., Reuss, M., Syldatk, C., Mattes, R., Siemann, M., Altenbuchner, J. Biotechnol. Bioeng. (2001) [Pubmed]

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